2008
DOI: 10.1016/j.cgh.2007.12.022
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Incidence of Autoimmune Diseases in Celiac Disease: Protective Effect of the Gluten-Free Diet

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Cited by 266 publications
(216 citation statements)
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“…However, subsequent studies have not confirmed the protective role of GFD [18,19]. Development of other autoimmune disease is more likely if the CD is diagnosed in young individuals with positive family history of CD [20].…”
Section: Celiac Disease and Other Autoimmune Diseasesmentioning
confidence: 96%
“…However, subsequent studies have not confirmed the protective role of GFD [18,19]. Development of other autoimmune disease is more likely if the CD is diagnosed in young individuals with positive family history of CD [20].…”
Section: Celiac Disease and Other Autoimmune Diseasesmentioning
confidence: 96%
“…Incluye casos en los que se presentan síntomas intestinales clásicos, diarrea crónica, pérdida de peso y afines; o síntomas extraintestinales no clásicos, como anemia, osteoporosis, trastornos neurológicos y dermatitis herpetiforme (Murray, 1999;Cosnes et al, 2008;Freitag et al, 2009;Sapone et al, 2012). Su sustrato morfológico se define por la presencia de un proceso inflamatorio cróni-co que afecta a la mucosa y submucosa del intestino delgado, y se caracteriza desde el punto de vista clínico por el surgimiento de diversas manifestaciones sistémicas (Rodríguez, 2010).…”
Section: Alergia Al Trigo E Intolerancia Al Glutenunclassified
“…However, a systematic review of studies reporting the long-term management of CD suggested that follow-up biopsy at 1-2 years after commencement of the GFD is recommended, and that if histological improvement is incomplete, biopsies probably should be performed again in 1-2 years. 6 Thus, the evaluated cohort of patients would not be useful to assess how persistent villous atrophy influenced mortality in CD, as the rate of follow-up small-bowel biopsy was quite low, the reason why these biopsies were taken was unknown, and there were no additional follow-up biopsies performed when histological improvement was incomplete. Likewise, follow-up biopsy in the study by Lebwohl et al…”
Section: A Tursimentioning
confidence: 99%
“…In our experience, subdividing the patients according to age, only the younger patients (5-30 years) showed significant improvement of histology within 12 months (P < 0.034); older patients (>30 years) showed histological improvement, but this was not statistically significant, even after 24 months on a GFD. 6 Gluten-free diet is generally advised to CD patients for three main reasons: treating symptoms related to the disease; preventing immunological gluten-related disorders; and preventing neoplastic complications. GFD and adherence to diet are considered the key factors in obtaining mucosal healing and in preventing occurrence of complications.…”
Section: A Tursimentioning
confidence: 99%