Incidence of bone metastasis in carcinoma buccal mucosa

Abstract

Introduction:Head and neck cancer is a leading health problem in India due to the habit of chewing tobacco and bad oral and dental hygiene. Carcinoma buccal mucosa is more common and is 2.5% of all malignancies at our center. Most of the patients present in stage III and IV and the survival in these cases is not very good. Bone metastasis in advanced cases of carcinoma buccal mucosa is rarely reported in the world literature.Materials and Methods:We present here cases developing bone metastasis in carcinoma buccal mucosa in last 5 years. These patients were young with loco-regionally advanced disease where bone metastasis developed within 1-year of definitive treatment.Results:The flat bones and vertebrae were mainly involved and the survival was also short after diagnosis of metastasis despite the treatment with local Radiotherapy and chemotherapy.Conclusion:The exact cause of metastasis cannot be proved, but the probability of subclinical seedling of malignant cells before the eradication of the primary tumor should be considered along with advanced local and nodal disease with high grade of tumor.

Distant Metastasis in Carcinoma Oral Cavity: Incidence and Prognostic Factors

“…8 Conventionally, the incidence of distant metastasis has been reported at around 8 to 13%. [3][4][5]9,10 The reported incidence is higher for our group of patients. One of factors could be higher proportion of gingivobuccal complex tumors in our series that has a better locoregional control as compared with tongue cancers.…”

“…In the literature, incidence of distant metastasis of head and neck cancer has been reported at around 10%. [3][4][5] There has been a gradual improvement in locoregional control posttreatment. At the same time, more patients are being diagnosed with distant metastasis from head and neck cancers.…”