Incidence of Dermatophytes in the San Francisco Bay Area

Abstract

A total of 1,101 patients was studied for the incidence and distribution of dermatophytes in the San Francisco Bay Area from 1974 to 1978. 267 dermatophytes were isolated and identified. Trichophyton rubrum and Triehophyton tonsurans were the most prevalent dermatophytes. T. rubrum caused 83% of tinea pedis, 82% of tinea unguium, 80% of tinea manuum and 66% of tinea cruris. T. tonsurans was the major cause of tinea capitis (60%) followed by Microsporum canis. Microsporum audouinii was not encountered in this survey.

Tinea manuum: A report of 18 cases observed in the metropolitan area of Milan and review of the literature

“…However, Trichophyton rubrum is the most frequently isolated species. 1,2,4,11,13,14,17,27,[33][34][35]39,40,42,46,48,53,55 Also, in our patients Trichophyton rubrum was the most frequently involved dermatophyte (6 out of 18 patients), followed by Microsporum canis (4 patients). Other dermatophytes responsible for tinea manuum are Epidermophyton floccosum, 20 Microsporum canis, 45 Trichophyton interdigitale, 37,47,50 Trichophyton mentagrophytes, 23,44 Trichophyton tonsurans, 3,28 Trichophyton verrucosum 21,36 and Trichophyton violaceum.…”

Metabolism of 3-lndolylacetic Acid during Percutaneous Absorption in Human Skin

“…Being weakly acidic (pK, = 4.75),18 the drug is largely ionized at skin pH (-5.01. 19 The retention of larger-than-expected amounts of the drug by these skin samples suggests that the drug may interact with protein(s) or other skin components. Figure 1 shows the percentage of the applied dose permeating skin from source C hourly during percutaneous absorption.…”

Trichophyton tonsuranstinea capitis in the San Francisco Bay area: increased infection demonstrated in a 20-year survey of fungal infections from 1974 to 1994

“…A survey between 1974 and 1978 in the San Francisco Bay area demonstrated this shift, but to a lesser degree: approximately 60% of tinea capitis infections (a total of 15 cases) were caused by T. tonsurans [4]. In the past several years we have noted a striking increase in both the number of patients and the percentage of cases with tinea capitis due to T. tonsurans.…”

“…As a corollary, the number of patient visits for tinea capitis at a paediatric dermatology practice at an affiliated hospital, San Francisco General Hospital (SFGH) were tabulated from 1986 to 1994. [4]. From 1974 to 1993 tinea capitis was the single most common source for positive cultures (27.5%) followed by tinea pedis (23.4%), tinea corporis (17-1%), tinea unguium (12-7%), tinea cruris (9.3%), tinea manure (5'9%) and tinea faciale (3-9%).…”