Incidence of differentiated thyroid carcinoma in multinodular goiter patients

Ghadhban, Basim R.; Kadam, Satar M.; sultan, Hanan Abdullatif

doi:10.1016/j.ijso.2018.10.004

Cited by 8 publications

(10 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The histopathological reports of studied patients were 10% papillary carcinoma, 3% follicular carcinoma and 3% medullary carcinoma. Our incidence was slightly higher than a study was conducted by Ghadhban in Iraq which showed that 21.7% of patients with nodular goiter had thyroid carcinoma (19) . Our frequency finding is also close to the frequency of differentiated thyroid carcinoma among nodular goiter found by Al-Salamah et al (20) study in Saudi Arabia of 21.3% that was detected by FNA and confirmed with histopathology.…”

Section: Discussioncontrasting

confidence: 74%

Evaluation of the Incidence of Thyroid Cancer among Patients with Thyroid Nodules Attending to Suez Canal University Hospital

Ramadan

kammash

Abdel-Gawwad

et al. 2021

Suez Canal University Medical Journal

View full text Add to dashboard Cite

Background: Thyroid cancer is the most common endocrine carcinoma, as it accounts for almost 90% of all endocrine malignancies. Our objective was to determine prevalence of thyroid cancer in patients underwent thyroidectomy in Suez Canal University Hospital. Patients and Methods: Cross-sectional descriptive study was conducted on 81 patients attending to our surgical oncology outpatient who were candidate for total thyroidectomy or hemithyroidectomy. Patients were subjected to clinical examination including multinodular goiter or solitary nodule, complaint of patient: pressure manifestations, cosmetic disfigurement and thyrotoxicosis and cervical lymphadenopathy. Neck ultrasonography was done for cervical lymphadenopathy, solitary nodule or multi nodular, assessment by TI-RADS and size of nodule. Specimens were sent to our pathology department. Results: Mean age of the patients was 48.83±11.01 years.75% were females. The chief complaint was neck lump (46.9%) and pressure symptoms (45.7%). Fifty percent of the patients had thyroid nodular size 1-4cm and 69.2% of were multi-nodular.69.2% of the patients had total thyroidectomy while 30.8% had hemi-thyroidectomy. Incidence of thyroid carcinoma was 26% as: papillary (18.5%), follicular carcinoma (3.7%), medullary carcinoma (2.5%) and anaplastic (1.2%). Thyroid carcinoma was associated with solitary nodule (55%), in the left lobe (42.8%), cervical lymph node (30%) and TIRADS 5 (42.8%). Conclusion: Incidence of thyroid carcinoma in Suez Canal University hospital is 26%. The most frequent histopathology type is papillary carcinoma. Females were the most affected. The pressure symptom was the most complaint in benign nodules while neck lump was the most common in malignant nodules. TIRADS 5 was the most frequent in all malignant nodules.

show abstract

Section: Discussioncontrasting

confidence: 74%

Evaluation of the Incidence of Thyroid Cancer among Patients with Thyroid Nodules Attending to Suez Canal University Hospital

Ramadan

kammash

Abdel-Gawwad

et al. 2021

Suez Canal University Medical Journal

View full text Add to dashboard Cite

show abstract

“…The highest numbers of our patients were in the third decade, which was differ from previous study [12], who found that the higher age group affected was 40-49 years. This was attributed to the difference between the studied samples.…”

Section: Discussioncontrasting

confidence: 99%

“…Iraq is an endemic area for goiter, mostly in northern and middle parts [1] because of the lack of iodine in soil and in the water supply. In addition, that most of our patients were females as compared to males: a finding consistent with many previous studies [5,6,[9][10][11][12][13].…”

Section: Discussionsupporting

confidence: 93%

Indications and complications of thyroidectomy in Al-Ramadi teaching hospital

Saleh¹,

Fakhree²,

Al-Ani³

2020

MMJ

View full text Add to dashboard Cite

Thyroidectomy is one of the common operations performed worldwide. It is a main option of treatment for different benign and malignant thyroid problems. Despite improvements in procedures have decreased mortality and even and morbidity rates to a minimum; however, postoperative complications remain a major concern among surgeons. We aimed to evaluate the indications and complications of thyroidectomy. A Prospective study was conducted at Al-Ramadi Teaching Hospital/Ramadi city/Iraq during the period from January 2009 to January 2010. There were 130 patients underwent thyroidectomy. A demographic and clinical data for each patient was recorded to assess indications and complications of different types of thyroidectomies. The majority of the patients were females (93{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47}). The most age group affected was 21-30 years (41.54{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47}). Pressure symptoms were accounting for 61.54{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47} of the indications. Thyroid enlargement in euthyroid states (80{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47}) was the common presenting state. Subtotal thyroidectomy (58.46{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47}) was the commonest procedure. Out of 130 patients, 36 patients (27.69{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47}) were suffered from complications. The 2 most common complications encountered in the study were hypocalcemia (61.11{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47}) and recurrent laryngeal nerve palsy (5.38{df6391716bcab23f197eab8ba5a452daee5812a1941604c42f67c7803ea6be47}). In conclusion, subtotal thyroidectomy is a common procedure in our hospital. Compressive complaints were the most common indication. Hypocalcemia and recurrent laryngeal nerve palsy were the 2 most postoperative complications.

show abstract

“…Since previous studies had yielded widely disparate results regarding the frequency of malignancy in MNG, this study was conducted to gather local evidence to improve the management of these patients and to hail TT as the standard treatment option in MNG. The mean age of patients or subjects in our comprehensive study was 42.89 ± 8.75 years, which was comparable to the study done by [13,18]. Our findings were close to those of Imad et al, reporting an 11.2% incidence of cancer in MNG [19].…”

Section: Discussionsupporting

confidence: 90%

Frequency and Type of Thyroid Carcinoma in Patients With Multinodular Goiter

Amin¹,

Amjad²,

Farman³

et al. 2023

Cureus

View full text Add to dashboard Cite

BackgroundThis study aimed to investigate the incidence and subtype of thyroid cancer in multinodular goitre (MNG) patients who underwent total thyroidectomy. MethodologyA cross-sectional study was conducted at the Khyber Teaching Hospital, screening 207 MNG patients who received complete thyroidectomies between July and December 2022. The senior consultant diagnosed thyroid cancer based on a complete history, physical examination, and laboratory and radiological studies. Ultrasound-guided fine-needle aspiration cytology was performed by a senior consultant radiologist. Bethesda categories for all lesions were recorded. All patients underwent thyroidectomy, and the diagnosis of thyroid cancer was confirmed on histopathology. ResultsA total of 207 patients were included in the study, with a mean age of 45.55 ± 8.75 years. Out of 207 patients, 24 (11.59%) were diagnosed with thyroid cancer. Out of 62 male patients, 15 (7.25%) had thyroid cancer. Out of 145 female patients, only nine had cancer (p < 0.001). Nine patients with thyroid cancer had a body mass index (BMI) below 18, compared to only five patients with a BMI of more than 30 kg/m 2 . The difference in age distribution was not significant in our study (p = 0.102). ConclusionIn conclusion, our study sheds light on the frequency and potential risk factors associated with thyroid cancer in patients with multinodular goiter. Our findings reveal that papillary thyroid carcinoma is the most commonly observed form of thyroid cancer in this patient population, with around 12 percent of patients diagnosed with thyroid cancer. Notably, our study highlights that male patients and those with a lower BMI may have a greater risk of developing thyroid cancer in the context of multinodular goiter. The findings of this study have important implications for the care and follow-up of MNG patients who receive total thyroidectomy. Further research is needed to investigate the type and prognosis of thyroid cancer in patients with MNG.

show abstract

Incidence of differentiated thyroid carcinoma in multinodular goiter patients

Cited by 8 publications

References 38 publications

Evaluation of the Incidence of Thyroid Cancer among Patients with Thyroid Nodules Attending to Suez Canal University Hospital

Evaluation of the Incidence of Thyroid Cancer among Patients with Thyroid Nodules Attending to Suez Canal University Hospital

Indications and complications of thyroidectomy in Al-Ramadi teaching hospital

Frequency and Type of Thyroid Carcinoma in Patients With Multinodular Goiter

Contact Info

Product

Resources

About