Incidence of Duodenal Ulcer and its Surgical Management in a Teaching Hospital in Bangladesh

Alam, Meer Mahbubul

doi:10.1177/004947559502500206

Cited by 10 publications

(6 citation statements)

References 6 publications

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“…After screening the titles, 395 abstracts and 119 complete articles were reviewed, and 88 were selected for detailed evaluation. Of these, 59 were rejected for the reasons as follows: the study population was not a general population or the IRs were reported for NSAID users and non‐users, but no data were provided for estimating incidence among the general population ( n = 15); the outcome was UGIB, but the percentage of bleeding cases caused specifically by peptic ulcer was not provided ( n = 5); the same population was used by different studies ( n = 11), and only the most recent one is included; no IR estimates, person–time, or number of cases were available ( n = 13); the measure of frequency was prevalence rather than incidence ( n = 4); only mortality or operation rate was reported ( n = 9); and the outcome was DU or GU alone ( n = 1) . We excluded another study because it used a rough approximation of population at risk (denominator); moreover, it was the only eligible article from a non‐Western country .…”

Section: Resultsmentioning

confidence: 99%

Systematic review of peptic ulcer disease incidence rates: do studies without validation provide reliable estimates?

Lin

Rodrı́guez

Hernández–Dı́az

2011

Pharmacoepidemiology and Drug

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We found that the IR of uncomplicated PUD was in the order of one case per 1000 person-years in the general population, and that the IR of peptic ulcer complications was around 0.7 cases per 1000 person-years. Comparisons of IR estimates among studies need to take into account disease definition and other study characteristics, particularly whether outcome validation was performed in computerized claims. The use of claims to identify PUD cases might overestimate the IR by around 45%.

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Section: Resultsmentioning

confidence: 99%

Systematic review of peptic ulcer disease incidence rates: do studies without validation provide reliable estimates?

Lin

Rodrı́guez

Hernández–Dı́az

2011

Pharmacoepidemiology and Drug

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“…The advances in the medical treatment of the peptic ulcer disease have led to a dramatic decrease in the number of elective surgeries performed. However, the number of patients undergoing surgical intervention for complications such as perforation remains relatively unchanged or has increased [ 21 , 22 ]. Such patients present with the classical signs and symptoms of peritonitis, and need early surgery for a favourable outcome.…”

Section: Discussionmentioning

confidence: 99%

Untitled

Gupta

Kaushik

2006

World J Emerg Surg

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Peritonitis is a common emergency encountered by surgeons the world over. This paper aims to provide an overview of the spectrum of peritonitis seen in the East. Studies dealing with the overall spectrum of secondary peritonitis in various countries of this region were identified using Pubmed and Google. These were analyzed for the site and cause of perforation and the mortality. It was observed that perforation of duodenal ulcers was the most the commonly encountered perforations. These are followed by small bowel and appendicular perforations. Colonic perforations were uncommon. The overall mortality ranges between 6-27%.

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“…2 The elective operative management of peptic ulcer have drastically reduced but the cases that end up with perforations are still same or rather increased. 7 In present study, author noted these patients came with classical features of peritonitis and showed pneumoperitoneum on the X-ray. Immediate surgeries resulted in a favourable outcome.…”

Section: Duodenal Perforationsmentioning

confidence: 52%

Clinical study and management of small bowel perforation in a tertiary care teaching institute

Bhanuprakash¹,

Aruna²,

Shetty³

2018

Int Surg J

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Background: Small bowel perforation is one of the most common abdominal surgical emergencies encountered in present study region. Late presentation makes them a diagnostic and treatment dilemma. The aim of present study was to determine the age, sex, incidence, etiological factors, clinical features and various surgical procedures for small bowel perforations and its complications in the setup.Methods: Present study is a prospective observational study of 100 cases, conducted in a single teaching institute from October 2015 to December 2016. Various data such as presentation by the patient, age and sex incidence, etiologies, pathological features, morbidity and mortality associated with the causation and management were evaluated, tabulated and assessed. By analyzing the data, common etiologies of small bowel perforation, the most appropriate modality of investigation, treatment, and complications associated with different methods of management and possible ways to prevent them were studied.Results: Among all small bowel perforation, duodenal perforation (70%) was the commonest cause of small bowel perforation followed by ileal (23%) and jejunal (7%) perforations. The most common causes of ileal perforation was typhoid (47.8%) followed by tuberculosis (13%) and traumatic (13%). Overall mortality in small bowel perforation was 15%, with ileal perforation (39%) showing higher mortality rate than duodenal perforation (8.5%). Wound infection, toxaemia, uraemia, hypotension, and respiratory complications were common complications, more commonly noted in cases of ileal perforation.Conclusions: The study showed that effective pre-operative management with adequate fluid resuscitation, immediate operative intervention and good post-operative care led to better outcomes in these cases. Hence timely diagnosis and prompt management is the gold standard for favourable outcome in patients with small bowel perforation.

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Incidence of Duodenal Ulcer and its Surgical Management in a Teaching Hospital in Bangladesh

Cited by 10 publications

References 6 publications

Systematic review of peptic ulcer disease incidence rates: do studies without validation provide reliable estimates?

Systematic review of peptic ulcer disease incidence rates: do studies without validation provide reliable estimates?

Untitled

Clinical study and management of small bowel perforation in a tertiary care teaching institute

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