Incidence of gynaecological cancer during the COVID-19 pandemic: A population-based study in the Netherlands

Oymans, Eline J.; Kroon, Cor D. de; Bart, Joost; Nijman, Hans W.; Aa, Maaike A. van der

doi:10.1016/j.canep.2023.102405

Cited by 3 publications

(1 citation statement)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Second, we used data spanning from 1997 to 2016 as the basis for making future predictions. This data range is unaffected by the delayed diagnosis and registration of cancer cases that occurred due to the COVID-19 pandemic [56]. Consequently, our short-to medium-term projections for cervical cancer incidence may be biased by the COVID-19 pandemic.…”

Section: Strengths and Limitationsmentioning

confidence: 97%

Projected Time for the Elimination of Cervical Cancer Under Various Intervention Scenarios: Age-Period-Cohort Macrosimulation Study

Chen,

et al. 2024

JMIR Public Health Surveill

View full text Add to dashboard Cite

Background The World Health Organization aims for the global elimination of cervical cancer, necessitating modeling studies to forecast long-term outcomes. Objective This paper introduces a macrosimulation framework using age-period-cohort modeling and population attributable fractions to predict the timeline for eliminating cervical cancer in Taiwan. Methods Data for cervical cancer cases from 1997 to 2016 were obtained from the Taiwan Cancer Registry. Future incidence rates under the current approach and various intervention strategies, such as scaled-up screening (cytology based or human papillomavirus [HPV] based) and HPV vaccination, were projected. Results Our projections indicate that Taiwan could eliminate cervical cancer by 2050 with either 70% compliance in cytology-based or HPV-based screening or 90% HPV vaccination coverage. The years projected for elimination are 2047 and 2035 for cytology-based and HPV-based screening, respectively; 2050 for vaccination alone; and 2038 and 2033 for combined screening and vaccination approaches. Conclusions The age-period-cohort macrosimulation framework offers a valuable policy analysis tool for cervical cancer control. Our findings can inform strategies in other high-incidence countries, serving as a benchmark for global efforts to eliminate the disease.

show abstract

Section: Strengths and Limitationsmentioning

confidence: 97%

Projected Time for the Elimination of Cervical Cancer Under Various Intervention Scenarios: Age-Period-Cohort Macrosimulation Study

Chen,

et al. 2024

JMIR Public Health Surveill

View full text Add to dashboard Cite

show abstract

Rekonstruktion onkologischer Defekte im Becken-Perinealbereich – Bericht zum Konsensus-Workshop im Rahmen der 44. Jahrestagung der DAM 2023 in Bern, CH

Kappos,

Wendelspiess,

Stoffel

et al. 2024

Handchir Mikrochir Plast Chir

View full text Add to dashboard Cite

ZusammenfassungDie chirurgisch-onkologische Therapie von Malignomen im Becken- und Perinealbereich geht mit einer hohen Komplikationsrate und Morbidität für Patientinnen und Patienten einher. Moderne multimodale Therapiekonzepte, wie etwa beim Anal- oder Rektumkarzinom mit neoadjuvanter Radio-Chemotherapie, erhöhen die Langzeit-Überlebensrate und senken das lokale Rezidivrisiko. Gleichzeitig geht die zunehmende chirurgische Radikalität und die höhere onkologische Sicherheit bei weiten Resektionsgrenzen zwangsläufig mit größeren und durch die Bestrahlung komplexeren Gewebedefekten am Beckenboden, perineal und sakral einher. Die plastisch-chirurgische Rekonstruktion von komplexen Defekten im Becken-Perinealbereich nach onkologischer Resektion bleibt daher nach wie vor herausfordernd. Das rekonstruktive Rüstzeug und somit die Behandlung solcher Defekte ist breit und reicht von lokalen und regionalen Lappenplastiken, über muskelbasierte bis hin zu mikrovaskulären und perforatorbasierten Verfahren. Während die Verwendung von Lappenplastiken mit einer mittlerweile in der Literatur gut dokumentierten, signifikanten Reduktion der postoperativen Komplikationen im Vergleich zum primären Verschluss einhergeht, fehlt es weiterhin an belastbaren Daten, welche die postoperativen Ergebnisse verschiedener rekonstruktiver Ansätze direkt miteinander vergleichen. Zudem zeigt die aktuellen Datenlage, dass die Erfassung der Lebensqualität dieser Patienten nur selten standardisiert erfolgt. Im Konsensus-Workshop der 44. Jahrestagung der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie zum Thema «Rekonstruktion onkologischer-Defekte im Becken-Perinealbereich» wurde die aktuelle Literatur diskutiert und Empfehlungen zur Rekonstruktion komplexer Defekte in diesem Bereich erarbeitet. Das Ziel dieses Workshops bestand darin, Wissenslücken zu identifizieren und soweit möglich einen Expertenkonsens zu etablieren, um die Qualität in der Rekonstruktion auf diesem anspruchsvollen Gebiet zu gewährleisten und kontinuierlich zu verbessern. Zudem wurde der Stellenwert vom «patient-reported outcome measure» in der Beckenrekonstruktion hervorgehoben und der Wille für dessen flächendeckenden Einsatz in einer patienten-zentrierten Gesundheitsversorgung festgehalten.

show abstract

Impact of the COVID-19 Pandemic on Tumor Stage and Pathohistological Parameters of Vulvar Cancer

Klamminger,

Bitterlich,

Nigdelis

et al. 2024

JCM

View full text Add to dashboard Cite

Background/Objectives: Vulvar cancer (VC) comprises a small fraction of female neoplasms with notable high-incidence clusters among German regions. Despite a proposed impact of nationwide lockdowns in response to the COVID-19 pandemic on oncological diseases, the effect on VC staging and tumor characteristics remains yet to be resolved; therefore, analyzing pathological data from patients with squamous cell VC pre-, during, and post-COVID in a high-incidence region may offer insights into potential epidemiological and clinical trends. Methods: We identified a total of 90 patients who were diagnosed at the Institute of Pathology, University Hospital Saarland, between 2018 and 2023, and defined three distinct cohorts: a pre-COVID cohort (2018–2019), a COVID cohort (2020–2021), and a post-COVID cohort (2022–2023). Histomorphological data were collected from the individual patient reports and statistically analyzed using Fisher’s exact test or the Kruskal–Wallis test. Results: Although we found no statistically significant differences in age, T-stage, perineural infiltration, blood vessel infiltration, resection status, grading, or resection margin between our three cohorts, surprisingly, we determined a greater extent of lymphovascular infiltration (Fisher’s exact test; p = 0.041), as well as deeper tumor infiltration depth (Kruskal–Wallis test; p < 0.001) before the COVID-19 pandemic. Furthermore, we did not identify any soft indications of abnormalities in patient care within our center (unchanged status of the resection margins across all three cohorts). Conclusions: Our results clearly do not support a negative affection of clinical or pathobiological characteristics of VC during or after the pandemic. However, final assessments regarding the pandemic’s effect on VC require additional study approaches in various regions, preferably with future extended timeframes of a longer follow-up.

show abstract

Incidence of gynaecological cancer during the COVID-19 pandemic: A population-based study in the Netherlands

Cited by 3 publications

References 23 publications

Projected Time for the Elimination of Cervical Cancer Under Various Intervention Scenarios: Age-Period-Cohort Macrosimulation Study

Projected Time for the Elimination of Cervical Cancer Under Various Intervention Scenarios: Age-Period-Cohort Macrosimulation Study

Rekonstruktion onkologischer Defekte im Becken-Perinealbereich – Bericht zum Konsensus-Workshop im Rahmen der 44. Jahrestagung der DAM 2023 in Bern, CH

Impact of the COVID-19 Pandemic on Tumor Stage and Pathohistological Parameters of Vulvar Cancer

Contact Info

Product

Resources

About