Incidence of hepatitis A and hepatitis E viruses and norovirus and rotavirus in fish and shrimp samples caught from the Persian Gulf

Amroabadi, M. Alipour; Rahimi, Ebrahim; Shakerian, Amir; Momtaz, Hassan

doi:10.1590/1678-4162-11742

Cited by 10 publications

(6 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…HAV has been reported in approximately 1% of fish and shrimp harvested from the Persian Gulf, confirming that sashimi can also be a source of infection [ 13 , 22 , 23 ]. Therefore, in addition to salted clams, which have already been identified as infectious agents, existing probable sources of infection such as raw shellfish, including sashimi and oysters, and the intake of other raw foods should continue to be investigated and managed.…”

Section: Discussionmentioning

confidence: 99%

A case-control study of acute hepatitis A in South Korea, 2019

Hyun

Yoon²,

Lee

2022

PHRP

View full text Add to dashboard Cite

Objectives: We aimed to reconfirm the source of hepatitis A virus (HAV) infection through epidemiological and genotype investigations of individual cases in a 2019 outbreak in South Korea.Methods: We investigated food intake histories, associations with hepatitis A, and genotypes of HAV in 31 patients with hepatitis aged 20 to 49 years registered in the integrated disease and health management system during December 1–7, 2019 (case group) and in 35 sex- and age-matched people without a history of HAV vaccination or infection among patients’ families and colleagues (control group).Results: The consumption of salted clams was a significant factor (odds ratio, 4.33; 95% confidence interval, 1.32–14.18) in the risk factor analysis of food intake history. HAV genotypes were analyzed in 24 of 31 patients. Type IA and type IIIA were found in 23 and 1 cases, respectively.Conclusion: Salted clams are considered to have been the source of HAV infection at 49 weeks of the HAV outbreak in 2019; this result was consistent with that of a previous epidemiological investigation conducted by the Korea Disease Control and Prevention Agency in September 2019. Therefore, monitoring of the production and distribution of salted clams needs to be continued.

show abstract

Section: Discussionmentioning

confidence: 99%

A case-control study of acute hepatitis A in South Korea, 2019

Hyun

Yoon²,

Lee

2022

PHRP

View full text Add to dashboard Cite

show abstract

“…Although vaccinations against these viruses have been produced, not all people, especially in low-income countries, have access to them (9). This emphasizes how urgently more work has to be done to guarantee that vaccinations are available and inexpensive for all populations, regardless of their nancial situation (5,10,11) .…”

Section: Introductionmentioning

confidence: 99%

Development of a Novel Bivalent Vaccine Candidate against Hepatitis A Virus and Rotavirus Using Reverse Vaccinology and Immunoinformatics

Yarmohammadi,

Sepahi,

Hamidi-fard

et al. 2024

Preprint

View full text Add to dashboard Cite

Hepatitis A virus (HAV) and rotavirus are mainly transmitted through fecal-oral and person-to-person contact, which cause severe gastrointestinal complications and liver diseases. This work used reverse vaccinology and immunoinformatic methods to create a novel bivalent vaccination against the rotavirus and HAV. The amino acid sequences of HAV-rotavirus proteins (VP1 and VP8*) were retrieved from GenBank. Multi-epitope DNA structures. Various computational approaches were employed to predict highly conserved regions and the most immunogenic B-cell and T-cell epitopes of VP8 and VP1 of rotavirus and HAV proteins in both humans and BALB/c. Moreover, the predicted fusion protein was analyzed regarding primary and secondary structures and homology validation. In this study, we used two highly conserved peptide sequences of VP8 and VP1 of rotavirus and HAV that induce T and B cell immunogenicity. According to T-cell epitope prediction, this area comprises 2713 antigenic peptides for HLA class II and 30 HLA class I antigenic peptides, both of which are virtually entirely conserved in the Iranian population. In this study, validation as well as analysis of the secondary and three-dimensional structure of the VP8*-rotavirus + AAY + HAV-VP1 fusion protein, with the aim of designing a multi-epitope vaccine with different receptors such as complications. TLR), 3,4 high immunogenic binding ability with immunological properties and interaction between multi-epitope target and TLR receptors were predicted, and it is expected that the target protein fusion has stable antigenic potency and compatible half-life. The above is suggested as universal vaccination programs.

show abstract

“…Additionally, they contain lipids and essential fatty acids, including long-chain polyunsaturated fatty acids and monounsaturated fatty acids. Shellfish also provide various minerals, such as calcium, sodium, magnesium, zinc, potassium, copper, selenium, and iron, as well as vitamins A, B, D, E, K, niacin, and folic acid (1). Their consumption is recommended for all people around the world.…”

Section: Introductionmentioning

confidence: 99%

“…They are usually transmitted by the fecal-oral route and by consuming contaminated food and water. Norovirus (NoV), hepatitis A virus (HAV), hepatitis E virus (HEV), and rotavirus (RoV) are the most significant enteric viruses with numerous foodborne aspects (1,3). Several outbreaks of viral foodborne diseases have been reported due to consuming contaminated seafood products, particularly shellfish (1,4).…”

Section: Introductionmentioning

confidence: 99%

Presence of Enteric Viruses in Shellfish Samples from the Persian Gulf

2023

ARI

View full text Add to dashboard Cite

Shellfishes are significant economic and nutritious seafood amongst people of different countries. Seafood products, particularly shellfish samples, are potential reservoirs of enteric viruses. This research investigated the incidence of RoV, NoV GI and GII, HAV, and HEV in shellfish samples from the Persian Gulf, Iran. One hundred and fifty shellfish samples were collected. RNA extraction and cDNA synthesis was performed using commercial kits. The real-time PCR assessed the presence of enteric viruses in extracted cDNA samples. Thirty-two out of 150 (21.33%) shellfish samples were contaminated with enteric viruses. Prevalence of NoV GI, NoV GII, HAV, and RoV amongst shellfish samples were 8.00%, 11.33%, 1.33%, and 0.66%, respectively. There were no contaminated shellfish samples with HEV. Simultaneous prevalence of HAV and NoV GI and HAV and NoV GII viruses were 0.66% and 0.66%, respectively. Examined viruses had a higher prevalence in shellfish samples collected through the winter season (P < 0.05). Prevalence of HAV, RoV, NoV GI, and NoV GII amongst shellfish samples collected through the winter season was 2.85%, 9.09%, 11.90%, and 20%, respectively. To the best of our knowledge, this is the first report of the incidence of enteric viruses, particularly HAV, NoV GI, NoV GII, and RoV, in shellfish samples from the Persian Gulf, Iran. Shellfish samples may serve as a potential source of enteric viruses for the human population. Therefore, routine viral assessments should be conducted. Completely cooking shellfish samples before consumption can significantly reduce the risk of HAV, RoV, NoV GI, and NoV GII infections. Furthermore, given the export value and importance of shellfish samples, their microbial quality and safety should be routinely monitored.

show abstract

Incidence of hepatitis A and hepatitis E viruses and norovirus and rotavirus in fish and shrimp samples caught from the Persian Gulf

Cited by 10 publications

References 38 publications

A case-control study of acute hepatitis A in South Korea, 2019

A case-control study of acute hepatitis A in South Korea, 2019

Development of a Novel Bivalent Vaccine Candidate against Hepatitis A Virus and Rotavirus Using Reverse Vaccinology and Immunoinformatics

Presence of Enteric Viruses in Shellfish Samples from the Persian Gulf

Contact Info

Product

Resources

About