Incidence of hypoparathyroidism after radical surgery for thyroid carcinoma and autotransplantation of parathyroid glands

Assessment of parathyroid autotransplantation for preservation of parathyroid function after total thyroidectomy

“…4,8,9,[15][16][17] One exception to this uniform success was that of Ohman et al, 18 who reported earlier in 1978 a 43% rate of permanent hypoparathyroidism after parathyroid autotransplantation. The poor result was attributed to transplantation of insufficient parathyroid tissue.…”

“…First, PTH acts on bone to increase the extracellular fluid calcium concentration by increasing the activity of osteoclasts. 15,28 Second, it stimulates renal synthesis of the active vitamin D 3 metabolite 1,25(OH2)D3, which in turn acts as a regulator of intestinal calcium absorption. In other words, there was a lag period between the recovery of the serum PTH and serum ionized calcium, because there must be some time for the homeostasis mechanism of blood calcium to be fully established.…”

Prediction of in vivo function of human parathyroid tissue autografts by in vitro testing

“…In reoperative parathyroid surgery the incidence is 30% [18], or 18% [19], with 60% of the latter group having at least transient hypoparathyroidism. In operations for papillary carcinoma of the thyroid, the incidence varies between 6% and 8% [20,21]. The present group of patients undergoing reoperation following multiple prior explorations had a 36% incidence of hypoparathyroidism.…”

Störungen des Kalziumstoffwechsels nach Schilddrüsenresektionen. Eine Analyse wesentlicher Einflussfaktoren

“…Postoperative Hypokalzämie und Hypoparathyreoidismus werden nicht einheitlich definiert und treten mit unterschiedlicher Häufigkeit auf [9,14,20]. Manche Autoren [1, 10,21] schlieûen bereits eine rein laborchemische Hypokalzämie ein.…”