Incidence of kidney stones in kidney transplant recipients: A systematic review and meta-analysis

Abstract

AIMTo evaluate the incidence and characteristics of kidney stones in kidney transplant recipients.METHODSA literature search was performed using MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews from the inception of the databases through March 2016. Studies assessing the incidence of kidney stones in kidney transplant recipients were included. We applied a random-effects model to estimate the incidence of kidney stones.RESULTSTwenty one studies with 64416 kidney transplant patients were included in the analyses to assess the incidence of kidney stones after kidney transplantation. The estimated incidence of kidney stones was 1.0% (95%CI: 0.6%-1.4%). The mean duration to diagnosis of kidney stones after kidney transplantation was 28 ± 22 mo. The mean age of patients with kidney stones was 42 ± 7 years. Within reported studies, approximately 50% of kidney transplant recipients with kidney stones were males. 67% of kidney stones were calcium-based stones (30% mixed CaOx/CaP, 27%CaOx and 10%CaP), followed by struvite stones (20%) and uric acid stones (13%).CONCLUSIONThe estimated incidence of kidney stones in patients after kidney transplantation is 1.0%. Although calcium based stones are the most common kidney stones after transplantation, struvite stones (also known as “infection stones”) are not uncommon in kidney transplant recipients. These findings may impact the prevention and clinical management of kidney stones after kidney transplantation.

Incidence and characteristics of kidney stones in patients with horseshoe kidney: A systematic review and meta-analysis

“…Kidney stone disease, also known as nephrolithiasis, is a common problem worldwide,[ 1 2 3 4 5 6 7 8 ] with a prevalence of 7% in the adults, and ≥30% recurrence rate within 10 years. [ 1 3 9 ] The incidence of kidney stones is globally increasing with an estimated prevalence ranging up to 15%.…”

Health Needs and Self - Efficacy among Patients Post Kidney Transplantation: Outcomes of Intervention Guidelines

“…It offers the benefits of freedom from the daily dialysis , removal of dietary / fluid restrictions and improved quality of life (Urstad et al, 2013& Bajaj, 2011. Patients with Kidney transplantation are affected physiologically, psychologically and socially by the negative way, so it is important for such patients to meet their needs for improving the quality of life for them (Cheungpasitporn et al, 2016 ).The present study aimed to evaluate the effect of Intervention guidelines on health needs and self -efficacy among patients post kidney transplantation.…”

Minimal-invasive management of urological complications after kidney transplantation

“…The incidence of urolithiasis after KT is 1% after a median time of 28 months. The stone composition is merely calcium-based in 67%, struvite in 20% and uric acid in 13% [ 77 ]. Co-existing conditions of end-stage renal disease like hyperparathyroidism, hypercalciuria, hypophosphatemia, and UTI may increase the risk of calculi formation [ 78 , 79 ].…”