Incidence of malignancy in hormone therapy users with indeterminate calcifications on mammogram

Lochner, Denise M.; Brubaker, Katherine

doi:10.1016/j.ajog.2005.06.044

Cited by 4 publications

(6 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Searching was therefore updated to identify additional relevant studies from September 2004 (the last search) to January 2011. As described in Supplement Figure 3, 49 additional studies 64,66,73,81,89,94,98,146-187 were eligible, which resulted in 94 studies finally being included in our review.…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Risk Factors of Breast Cancer

Anothaisintawee

Wiratkapun

Lerdsitthichai

et al. 2013

Asia Pac J Public Health

143

View full text Add to dashboard Cite

The etiology of breast cancer might be explained by 2 mechanisms, namely, differentiation and proliferation of breast epithelial cells mediated by hormonal factors. We performed a systematic review and meta-analysis to update effects of risk factors for both mechanisms. MEDLINE and EMBASE were searched up to January 2011. Studies that assessed association between oral contraceptives (OC), hormonal replacement therapy (HRT), diabetes mellitus (DM), or breastfeeding and breast cancer were eligible. Relative risks with their confidence intervals (CIs) were extracted. A random-effects method was applied for pooling the effect size. The pooled odds ratios of OC, HRT, and DM were 1.10 (95% CI = 1.03-1.18), 1.23 (95% CI = 1.21-1.25), and 1.14 (95% CI = 1.09-1.19), respectively, whereas the pooled odds ratio of ever-breastfeeding was 0.72 (95% CI = 0.58-0.89). Our study suggests that OC, HRT, and DM might increase risks, whereas breastfeeding might lower risks of breast cancer.

show abstract

Section: Resultsmentioning

confidence: 99%

“… ‡ References 64, 66, 73, 81, 94, 98, 102-106, 108, 110-113, 115-118, 120, 123-130, 132-145, 147-151, 153…”

mentioning

confidence: 99%

See 1 more Smart Citation

Risk Factors of Breast Cancer

Anothaisintawee

Wiratkapun

Lerdsitthichai

et al. 2013

Asia Pac J Public Health

143

View full text Add to dashboard Cite

show abstract

“…At the same time, these factors are (apart from high BMI and smoking) associated with higher mammographic density and increased risk of breast cancer. Previously exogenous estrogens have been shown to be negatively associated with microcalcifications, 44,45 so has tobacco 7,10,13,46 . However, the majority of these studies investigated the breast arterial calcifications.…”

Section: Discussionmentioning

confidence: 99%

“…Previously exogenous estrogens have been shown to be negatively associated with microcalcifications, 44,45 so has tobacco. 7,10,13,46 However, the majority of these studies investigated the breast arterial calcifications.…”

Section: Mammographic Density and Genetic Predictors Of Microcalcifmentioning

confidence: 99%

Predictors of mammographic microcalcifications

Azam

Eriksson

Sjölander

et al. 2020

Intl Journal of Cancer

View full text Add to dashboard Cite

We examined the association between established risk factors for breast cancer and microcalcification clusters and their asymmetry. A cohort study of 53 273 Swedish women aged 30 to 80 years, with comprehensive information on breast cancer risk factors and mammograms, was conducted. Total number of microcalcification clusters and the average mammographic density area were measured using a Computer Aided Detection system and the STRATUS method, respectively. A polygenic risk score for breast cancer, including 313 single nucleotide polymorphisms, was calculated for those women genotyped (N = 7387). Odds ratios (ORs) and 95% confidence intervals (CIs), with adjustment for potential confounders, were estimated. Age was strongly associated with microcalcification clusters. Both high mammographic density (>40 cm2), and high polygenic risk score (80‐100 percentile) were associated with microcalcification clusters, OR = 2.08 (95% CI = 1.93‐2.25) and OR = 1.22 (95% CI = 1.06‐1.48), respectively. Among reproductive risk factors, life‐time breastfeeding duration >1 year was associated with microcalcification clusters OR = 1.22 (95% CI = 1.03‐1.46). The association was confined to postmenopausal women. Among lifestyle risk factors, women with a body mass index ≥30 kg/m2 had the lowest risk of microcalcification clusters OR = 0.79 (95% CI = 0.73‐0.85) and the association was stronger among premenopausal women. Our results suggest that age, mammographic density, genetic predictors of breast cancer, having more than two children, longer duration of breast‐feeding are significantly associated with increased risk of microcalcification clusters. However, most lifestyle risk factors for breast cancer seem to protect against presence of microcalcification clusters. More research is needed to study biological mechanisms behind microcalcifications formation.

show abstract

La consultation de suivi du THM. Conduite à tenir en cas de tumeur mammaire (clinique ou radiologique) et de microcalcifications. RPC Les femmes ménopausées du CNGOF et du GEMVi

Mathelin

Molière

2021

Gynécologie Obstétrique Fertilité & Sénologie

View full text Add to dashboard Cite

Incidence of malignancy in hormone therapy users with indeterminate calcifications on mammogram

Cited by 4 publications

References 8 publications

Risk Factors of Breast Cancer

Risk Factors of Breast Cancer

Predictors of mammographic microcalcifications

La consultation de suivi du THM. Conduite à tenir en cas de tumeur mammaire (clinique ou radiologique) et de microcalcifications. RPC Les femmes ménopausées du CNGOF et du GEMVi

Contact Info

Product

Resources

About