Incidence of meningitis in late onset sepsis

Bhagat, Roshi; Hussain, Sheikh Quyoom; Gattoo, Imran; Wani, Shafiq A.

doi:10.5455/2349-3291.ijcp20150507

Cited by 13 publications

(30 citation statements)

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“…In addition Umate et al was found lethargic (68.75%) and respiratory distress (72.60%). Temperature instability and seizure also found as independent factors associated with serious CNS complication [12][13][14]. That statement is strengthened by our results in which there was no temperature instability (96%) neither seizure (96%) most of our subjects had good outcome (70%).…”

Section: Discussionsupporting

confidence: 71%

Characteristics of neonatal late onset sepsis in Sanglah Hospital, Bali

Prayoga¹,

Kardana²,

Artana³

et al. 2021

GSC Adv. Res. Rev.

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Neonatal Late-Onset Sepsis (LOS) is a leading cause of mortality in the Neonatal Intensive Care Unit (NICU). The microbial characteristics of LOS are of primary importance in guiding clinical antisepsis practice, and strategies to prevent and treat neonatal LOS, in turn, influence the pattern of LOS pathogens. This study is a retrospective descriptive study with a cross-sectional approach conducted between 2016 until 2020 in the neonatal ward (level II-III) of the Sanglah General Hospital, Bali. Data collected consists of demography, clinical characteristics, laboratory results, and outcomes. Subjects in this study dominated by male (64%), gestational age > 37 weeks (56%), born ≥ 2.500 grams (54%), last mother education mostly in Senior High School (56%), spontaneous delivery method (54%) and 31 (62%) subjects were referral from other hospital and primary health care. Most of the subjects were lethargic (68%) and 15 (30%) subjects were died. Laboratory finding normal leukocyte, neutrophil, lymphocyte, hemoglobin, thrombocyte and IT ratio but have higher procalcitonin result. Poor outcome group were dominated by male, smaller gestational age, VLBW, and neonates who experience lethargy, temperature instability, respiratory distress and got positive blood culture.

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Section: Discussionsupporting

confidence: 71%

Characteristics of neonatal late onset sepsis in Sanglah Hospital, Bali

Prayoga¹,

Kardana²,

Artana³

et al. 2021

GSC Adv. Res. Rev.

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“…It has been found earlier as well that meningitis was present in 63% of the low body weight neonates having LOS and 62% of the preterm neonates were also having meningitis which again emphasizes which was found in the present work. 16 Higher frequency of meningitis among low birth weight and preterm neonates have also been described by other researches as well. 20,21 Umait S et al from India 12 also noted among neonates having LOS with meningitis, 73% and 77% were preterm and had low body weight which is in accordance to current findings.…”

Section: Figure-1 Frequency Of Meningitis In Neonatal With Late-onsesupporting

confidence: 52%

Meningitis in neonates having late onset sepsis.

Ahmad¹,

Hussain

Rafique³

et al. 2020

TPMJ

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Objectives: Majority of the researchers reporting incidence and etiology surrounding neonatal sepsis along with meningitis are from developed countries while limited work is noticed from developing countries where overall burden of these disease are immense. The current study was aimed to determine the frequency of meningitis in children having late-onset sepsis (LOS). Study Design: Descriptive Case Series study. Setting: Department of Pediatrics Medicine, Nishter Medical University Multan and DHQ Teaching Hospital, Dera Ghazi Khan. Period: From July to December 2019. Material & Methods: A total of 206 neonates of both gender, older than 72 hours, admitted and diagnosed with sepsis were enrolled. Meningitis was labeled in a neonate if his/her cerebrospinal fluid (CSF) contains > 30 leukocytes/mm3, and any one of these two: protein >200mg/dl or sugar <40mg/dl. Results: Out of a total of 206 neonates having LOS, majority, 111 (53.9%) were male and 73 (35.4%) were aged 3 to 7 days. Overall, mean weight was found to be 2.68+0.51 kg. A total of 84 (40.8%) neonates were preterm. Frequency of meningitis was found in 44 (21.4%) neonates. Neonates having low body weight and being preterm were noted to have significant associations (p value < 0.05) with meningitis. Conclusion: Frequency of meningitis in neonates with LOS was high. Low body weight and preterm neonates having LOS were found to have significant association with the presence of meningitis.

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“…[5][6][7] Studies in the UK have found that the incidence of meningitis varies from 1.3% to 3.5% in neonates with LOS. Two other studies from North India 9 and Central India 10 reported approximately 17% incidence of meningitis in neonates with LOS. However, there is a paucity of data from West India.…”

mentioning

confidence: 88%

An Observational Study to Evaluate the Incidence of Meningitis in Neonates With Late-Onset Sepsis

Kumar

Sahni

2020

IJMBS

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Introduction: Bacterial sepsis and meningitis continue to be major causes of morbidity and mortality in newborns, particularly in premature infants. The present study was undertaken to know the incidence of meningitis in neonates with late onset sepsis. Material and Methods: Hospital based observational study, conducted in department of Pediatrics, Shri krishna Medical College and Hospital Muzaffarpur Bihar India, conducted for a period of one year. 324 patients fulfilling the inclusion criteria were included and subjected to detailed history, clinical examination followed by investigations. Results: The annual incidence of meningitis in LOS was 15. The majority of patients (44.44%) presented in the age group of 3-7 days. In meningitis cases 100% cases were lethargic; seizures in 89%, fever in 53%. Blood culture was positive in 33.92% cases of meningitis. Meningitis was seen in 66.66% of proven gram negative sepsis as against 33.34 cases of proven gram positive sepsis and 14.28% expired with meningitis and 4.10% expired with no meningitis. Conclusions: Meningitis is common in late onset sepsis, associated with high mortality. Keywords: Meningitis, Preterm, LBW, Lumber puncture

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Incidence of meningitis in late onset sepsis

Cited by 13 publications

References 0 publications

Characteristics of neonatal late onset sepsis in Sanglah Hospital, Bali

Characteristics of neonatal late onset sepsis in Sanglah Hospital, Bali

Meningitis in neonates having late onset sepsis.

An Observational Study to Evaluate the Incidence of Meningitis in Neonates With Late-Onset Sepsis

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