Incidence of microalbuminuria in hypertensive patients

Abstract

The prevalence of microalbuminuria was assessed in 174 albustix negative hypertensive patients by estimating albumin in the morning random urine samples by immunoturbidimetric method within four hours of voiding of urine. The urine samples were not stored and collected without any preservatives. The urinary albumin was calculated in terms of ratio with respect to urinary creatinine and expressed as albumin creatinine ratio (mg/g). Out of 174 albustix negative hypertensives, 58 (33.3%) patients were found to have microalbuminuria. The prevalence of microalbuminuria in males and females was found to be 34% and 30.7% respectively. No correlation was found between the Body Mass Index (BMI) and albumin excretion (r 2 = 0.0271) and between duration of hypertension and urinary albumin excretion (r 2 = 0.0042). Prevalence of microalbuminuria in nonsmokers and non-alcoholic hypertensives was 20%. The prevalence in alcoholics, smokers and both smokers and alcoholics was found to be 35%, 42% and 41% respectively. The high prevalence of microalbuminuria than the various reported studies on the subject demands establishment of a screening programme for microalbuminuria, implementation of specific intervention methods and education of hypertensive patients about the consequences of smoking and alcohol on possible involvement of renal system.

A Study of Microalbuminuria in Essential Hypertension and Its Correlation With the Target Organ Damage

“…This finding was in accordance to the studies done by Hitha et al (7) and Sharma et al (8) Prevalence of microalbuminuria in our study was low when compared to the studies done by Sabharwal et al (9) and Bibek et al (10) In the present study, there was no significant difference between prevalence of microalbuminuria in men and women. This finding was in accordance to the study done by Sabharwal et al (9) and our finding was in contrary to the findings observed in the study done by Pontremoli et al (11) where microalbuminuria was observed to be more in males.…”

Protein creatinine index: A possible predictor of nephropathy in hypertensives, in Northern India

“…According to our study, PCI showed moderately positive correlation with MAP (r = 0.595, P b 0.05) and strong positive correlation with the duration of HTN (r = 0.745, P b 0.05). In contrast to our results Sabharwal et al observed no correlation between duration of HTN and albuminuria [6]. Urinary protein concentration demonstrated weak to moderately positive correlation with MAP (r = 0.397) and with duration of HTN (r = 0.433); urinary creatinine concentration showed weak negative correlation with MAP (r = −0.270) and with duration of HTN (r = −0.299).…”

“…HTN, a chronic disorder with increased systemic arterial blood pressure (BP) [4], and other lifestyle diseases are increasing the burden over the healthy functioning of kidneys [5]. N 33% of the Indians with systemic HTN develop microalbuminuria and progress to hypertensive nephropathy [6] which may eventually develop into end stage renal disease (ESRD).…”

Assessment of Microalbuminuria in Essential Hypertensives and Its Response to Angiotensin-Converting Enzyme Inhibitor Therapy

“…In our finding, the prevalence of microalbuminuria was 27.7% out of 300%. Palatini reported the prevalence of only 6% in 2005 [15] while Sabharwal et al in 2008 reported the 33.3% prevalence among 174 patients [16]. Pontremoli et al reported 8 % prevalence in their study [17].…”