Incidence of mild cognitive impairment - a systematic review

Luck, Tobias; Luppa, Melanie; Briel, S; Riedel-Heller, SG

doi:10.1055/s-0031-1277902

Cited by 36 publications

(54 citation statements)

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“…The observed prevalence of MCI in the studied population was about 7% at the last evaluation performed, lower than the prevalence described by the literature which can be up to 20%. [19] The low prevalence of MCI in this sample could be explained by the fact that higher education has been described as a protective factor for MCI and cognitive decline in elderly people [17,25] , and the sampled population was highly educated, with more than 80% of the sample having more than 12 years of education and 36.19% having more than 16 years of education.…”

Section: Discussionmentioning

confidence: 88%

“…It has been estimated that without changes in mortality or new effective prevention strategies or curative treatments, the number of affected people with dementia will double every 20 years reaching 81.1 million people by 2040. [17] Mild cognitive impairment (MCI) or Cognitive Impairment non dementia (CIND) [18] is a syndrome defined as cognitive decline greater than that expected for an individual's age and education level but that does not interfere notably with activities of daily life. [19] In addition, it differs from dementia, in that the cognitive impairment in dementia is more severe and widespread and has a substantial effect on daily function.…”

Section: Cognitive Impairmentmentioning

confidence: 99%

“…In the studies performed regarding MCI, it has been found that higher age, history of a diagnosis of hypertension, ethnicity and lower education are significant risk factors in the development of the condition. [17,21] In a study performed in elderly women in which lifestyle factors and comorbidities were evaluated regarding the development of cognitive impairment, results concluded that lifestyle risk factors, comorbid disorders and genetic factors contribute to the development of age-related cognitive impairment. [22] In particular, Rasmusssen et al noticed that obesity and depression were significantly associated with cognitive impairment, with OR values of 1.54 (95% CI=1.00-2.36) and 3…”

Section: Cognitive Impairmentmentioning

confidence: 99%

“…[24] Among other factors that can be associated with cognitive impairment, it has been described that higher years of education may have a protective effect on cognitive decline. [17] Related with education, it has been described that lower SES is associated with higher risk of MCI or CIND. [25] Their results show that high SES was associated with a 69% reduced risk of developing MCI/AD compared with low SES (OR=0.31, 95%CI 0.14-0.73, p<0.01).…”

Section: Cognitive Impairmentmentioning

confidence: 99%

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Cognitive decline and polypharmacy in an elderly population.

González¹

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Aging is associated with increased risk of chronic disease, comorbidities, and greater medication use. Polypharmacy, the concomitant use of 5 or more medications, has been associated with adverse health effects, and potentially cognitive decline. The proposed hypothesis is that polypharmacy increases the risk of cognitive decline in elderly people. Using longitudinal data from 572 participants from the New Mexico Aging Process Study cohort, the impact of polypharmacy on the Mini Mental State Examination (MMSE) scores and Mild Cognitive Impairment (MCI) was studied. The statistical analyses were performed using mixed linear regression multivariable models and generalized estimating equations, adjusting for important covariates. Polypharmacy was associated with a 0.11±0.09 decrease in MMSE scores (p-value=0.23) and an increased risk of MCI (odds ratio=1.95, 95% CI 0.40-9.43). The results suggest that polypharmacy may increase the rate of cognitive decline in elderly people. Larger studies in other populations are needed to support this hypothesis. v

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Section: Discussionmentioning

confidence: 88%

Section: Cognitive Impairmentmentioning

confidence: 99%

Section: Cognitive Impairmentmentioning

confidence: 99%

Section: Cognitive Impairmentmentioning

confidence: 99%

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Cognitive decline and polypharmacy in an elderly population.

González¹

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“…A prevalência de CCL varia consideravelmente de acordo com a região e população estudada (Luck et al, 2010). Os valores oscilam de 3% a até 42% (Ward et al, 2012), dependendo dos testes neuropsicológicos usados no rastreio, dos valores de cortes e das características socioeconômicas da população estudada (Brucki, 2013).…”

Section: Aspectos Gerais E Epidemiológicos Do Comprometimento Cognitiunclassified

Efeitos do treinamento aeróbio na cognição e no metabolismo cerebral em repouso em sujeitos com comprometimento cognitivo leve

Porto¹

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Predementia constructs: Mild cognitive impairment or mild neurocognitive disorder? A narrative review

Bermejo‐Pareja

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Ser

et al. 2020

Int J Geriat Psychiatry

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Background: Predementia is a heuristic umbrella concept to classify older adults with cognitive impairment who do not suffer dementia. Many diagnostic entities have been proposed to address this concept, but most of them have not had widespread acceptance. Aims: To review clinical definitions, epidemiologic data (prevalence, incidence) and rate of conversion to dementia of the main predementia constructs, with special interest in the two most frequently used: mild cognitive impairment (MCI) and minor neurocognitive disorder (miNCD). Methods: We have selected in three databases (MEDLINE, Web of Science and Google scholar) the references from inception to 31 December 2019 of relevant reviews, population and community-based surveys, and clinical series with >500 participants and >3 years follow-up as the best source of evidence. Main results: The history of predementia constructs shows that MCI is the most referred entity. It is widely recognized as a clinical syndrome harbinger of dementia of several etiologies, mainly MCI due to Alzheimer's disease. The operational definition of MCI has shortcomings: vagueness of its requirement of "preserved independence in functional abilities" and others. The recent miNCD construct presents analogous difficulties. Current data indicate that it is a stricter predementia condition, with lower prevalence than MCI, less sensitivity to cognitive decline and, possibly, higher conversion rate to dementia. Conclusions: MCI is a widely employed research and clinical entity. Preliminary data indicate that the clinical use of miNCD instead of MCI requires more scientific evidence. Both approaches have common limitations that need to be addressed.

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Incidence of mild cognitive impairment - a systematic review

Cited by 36 publications

References 0 publications

Cognitive decline and polypharmacy in an elderly population.

Cognitive decline and polypharmacy in an elderly population.

Efeitos do treinamento aeróbio na cognição e no metabolismo cerebral em repouso em sujeitos com comprometimento cognitivo leve

Predementia constructs: Mild cognitive impairment or mild neurocognitive disorder? A narrative review

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