Incidence of neural tube defects in Afyonkarahisar, Western Turkey

Onrat, Serap Tutgun; Seyman, H.; Konuk, M.

doi:10.4238/vol8-1gmr552

Cited by 37 publications

(32 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the current trial, all patients had lumbar lesions, and neurological and physical examinations of the upper extremities and trunk were normal. It was shown that the prevalence of neural tube defects is high in families with low educational level in our country (3,4,6,21). In concordance with these studies, 74.1% of mothers and 48.1% of fathers had primary education in our study.…”

Section: Discussionsupporting

confidence: 90%

“…Some studies have been published on the prevalence, incidence, and risk factors of neural tube defects in our country (3,4,6,21). This study explored the muscle functions of lower (21), it was found that meningomyelocele was mostly present in the lumbar area, which is similar to previous studies.…”

Section: Discussionsupporting

confidence: 79%

“…SB aperta is a midline defect that communicates with the external environment and includes myelomeningocele and meningocele (2). The prevalence estimate of SB is 3.5 per 10,000 live births in the USA (1), and it has been reported that in Turkey, the neural tube defect prevalence is 3-9 in 1,000 live births (3)(4)(5)(6).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Muscle Function of Lower Extremities in Children with Lumbar Spina Bifida: Impact on Functional Status

Ulus¹,

Tander²,

Akyol³

et al. 2014

Turk J Phys Med Rehab

View full text Add to dashboard Cite

ÖzetAmaç: Bu çalışmanın amacı spina bifidalı (SB) çocuklarda alt ekstremitelerin kas gücü, kas tonusu ve kontraktürlerinin ambulasyon ve fonksiyonel durum üzerine etkisinin değerlendirilmesi idi. Gereç ve Yöntemler: Spina bifidalı 54 çocuk çalışmaya alındı. Pediatrik Fonksiyonel Bağımsızlık Ölçümü (PFBÖ), tüm çocuklarda alt ekstremitelerde eklem hareket açıklığı, alt ekstremitelerin kas tonusu ve kas gücü, 36 aydan büyük çocukların ambulasyon seviyeleri değerlendirildi. Bulgular: Ambule olmayan ve fonksiyonel ambule olan 36 aydan büyük çocuklar arasında kas gücü ve kas tonusu açısından anlamlı fark vardı (p<0,001). Kas gücü ve kas tonusunun PFBÖ skorları üzerine anlamlı etkisi bulunmazken, kontraktür PFBÖ motor (p=0,001) ve PFBÖ kognitif-toplam (p<0,001) skorları üzerine etkisi bulundu. Otuz altı aydan büyük olan çocuklarda, ambulasyonun PFBÖ kognitif (p=0,019) ve PFBÖ motor-toplam (p<0,001) skorları üzerine anlamlı etkisinin olduğu bulundu. Sonuç: Alt ekstremitelerin kas gücü ve kas tonusu, SB'li çocukların ambulasyonunda önemli olabilir. Ambulasyon ve kontraktürler, bu çocukların fonksiyonel yeteneklerinin önemli belirleyicileri olabilirler. Anahtar Kelimeler: Spina bifida, ambulasyon, dizabilite AbstractObjective: The aim of this study was the evaluation of the impacts of muscle strength, muscle tone, and contractures of the lower extremities on ambulation and functional status in children with spina bifida (SB). The aims of this study were the determination of the demographical and clinical characteristics of Turkish children with spina bifida (SB) and the evaluation of the impacts of the clinical features on ambulation and functional status. Material and Methods: Fifty-four children with SB were included in the study. The Functional Independence Measure for Children (WeeFIM), range of motion in lower extremities, and muscle tone and muscle strength of the lower extremities in all children and the ambulation level of children older than 36 months were evaluated. Results: There were significant differences between the non-ambulant and functional ambulant children older than 36 months in terms of muscle strength and muscle tone (p<0.001). While no significant effects of muscle strength and muscle tone on WeeFIM scores were found (p>0.05), contracture was found to be effective on WeeFIM motor (p=0.001) and WeeFIM cognitive-total (p<0.001) scores by univariate analyses of variance. In children older than 36 months, significant effects of ambulatory status on WeeFIM cognitive (p=0.019) and WeeFIM motor-total (p<0.001) scores were found. Conclusion: Muscle strength and muscle tone of lower extremities may be important for ambulation of children with SB. Ambulatory status and contractures may be important determinants for functional abilities of these children.

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 79%

See 1 more Smart Citation

Muscle Function of Lower Extremities in Children with Lumbar Spina Bifida: Impact on Functional Status

Ulus¹,

Tander²,

Akyol³

et al. 2014

Turk J Phys Med Rehab

View full text Add to dashboard Cite

show abstract

“…Overall, the incidence of neural tube defects outside the European Union is much higher. To the east, in Turkey, according to Dogan H. (2005) and Onrat ST. (2009) the frequency of NTDs is close to four per one thousand births [11,12]. The different regions of Iran show a varying incidence of NTDs (1.27 to 4.2 per 1,000 births), and consanguinity is found in about one third of the cases (29.5%).…”

Section: Introductionmentioning

confidence: 99%

Maternal factors and associated anomalies in NTD fetuses from Tunisia

et al. 2013

View full text Add to dashboard Cite

show abstract

“…A study by Bati et al (2007) revealed that the incidence of NTD was 1.5 in 1000 births in all hospitals in Izmir. In Afyonkarahisar, the incidence of NTD was found to be 3.58 in 1000 live births (Onrat et al, 2009). Abnormalities of the central nervous system rank highest among studies investigating the registries of major congenital abnormalities in Denizli (31.1%) (Tomatir et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

Registries of cases with neural tube defects in Denizli, Turkey, 2004-2010

et al. 2014

View full text Add to dashboard Cite

ABSTRACT. Neural tube defects (NTD) are among the most common congenital abnormalities, with an incidence of 3 per 1000 live births in Turkey. In a study of major congenital abnormalities in the city of Denizli, Turkey, abnormalities of the central nervous system are particularly common (31.1%). The objective of this study was to develop a registry of cases with NTDs in Denizli. Cases that had been diagnosed with NTD between January 2004 and September 2010 in State Hospitals of Central Denizli were retrospectively examined. The diagnoses were established based on the ICD-10 criteria. A total of 250 subjects with NTD were identified, including 123 (49.2%) females and 127 (50.8%) males with a mean age of 13.72 ± 15.62 years (age range 1-81 years). Interestingly, spina bifida constituted a significant percentage of the cases (149 cases; 59.6%). In addition, 10 (4.0%) cases had hydrocephalus plus spina bifida. The second most common diagnosis was microcephaly, which included 70 cases (28.0%). Encephalocele was observed in only 2 cases (0.8%). Development of NTD is influenced by nutrition, socioeconomic factors, and the use of folic acid during the peri-conceptional period. Studies examining the effect of these factors on NTD in Turkey and a review of primary prevention measures are necessary.

show abstract

Incidence of neural tube defects in Afyonkarahisar, Western Turkey

Cited by 37 publications

References 38 publications

Muscle Function of Lower Extremities in Children with Lumbar Spina Bifida: Impact on Functional Status

Muscle Function of Lower Extremities in Children with Lumbar Spina Bifida: Impact on Functional Status

Maternal factors and associated anomalies in NTD fetuses from Tunisia

Registries of cases with neural tube defects in Denizli, Turkey, 2004-2010

Contact Info

Product

Resources

About