Incidence of periprosthetic joint infection after primary total hip arthroplasty is underestimated: a synthesis of meta-analysis and bibliometric analysis

Abstract

The American Musculoskeletal Society updated the diagnostic criteria for periprosthetic joint infection (PJI) in 2011 and 2018. However, the overall incidence of PJI since the introduction of these new standards has not been assessed. In order to fill this knowledge gap, a single-group meta-analysis was conducted using articles obtained from several databases, focusing on the incidence of PJI after primary total hip arthroplasty (THA). Our study revealed a significant difference in the incidence of PJI reported by different national or regional databases. Moreover, most cases of PJI were found to be underestimated. This highlights the crucial need for standardized diagnostic criteria and monitoring methods to accurately identify and track cases of PJI. Furthermore, a bibliometric analysis was conducted to provide a comprehensive overview of the current state of research on PJI after THA. This analysis explored the most productive countries, organizations, journals, and individuals in this research area. Additionally, it identified the research trends and hotspots of the last decade, highlighting the advancements and areas of focus in this field. By conducting these analyses, the study aims to contribute to the understanding of PJI after THA and provide valuable insights for clinicians, researchers, and policymakers involved in the management of this condition.

Upcoming evidence in clinical practice of two-stage revision arthroplasty for prosthetic joint infection

“…2 Department of Public Health, Orthopedic Unit, "Federico II" University, Naples, Italy. 3 Unit of Infectious Diseases, Department of Medicine, Surgery and Dentistry, "Scuola Medica Salernitana", University of Salerno, Baronissi, Italy. 4…”

“…Data obtained from the US Department of Veterans Affairs on a sample of around 80,000 patients undergoing primary total knee arthroplasty identified a percentage of patients with PJI approaching 2%, with the highest number of PJI cases diagnosed within 24 months from primary knee arthroplasty [ 2 ]. Further data obtained by a meta-analysis including articles investigating the incidence of PJI after primary hip arthroplasty highlight an incidence approaching 1%, with the highest number of cases among people aged ≥ 70 years and a great difference in terms of incidence among different countries [ 3 ].…”

The Antibacterial Properties of a Silver Multilayer Coating for the Prevention of Bacterial Biofilm Formation on Orthopedic Implants—An In Vitro Study

“…With a 5-year mortality rate of >21%, PJI is a major problem in orthopedic surgery [1]. The incidence of PJI is estimated to be 1%-2% after primary surgery [2][3][4][5][6][7]. In hip and knee arthroplasty surgery, PJI is the main cause of 15% and 25% of all revisions, respectively [8][9][10][11].…”