2011
DOI: 10.1097/ta.0b013e3182282574
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Incidence of Pulmonary Embolus in Combat Casualties With Extremity Amputations and Fractures

Abstract: The cumulative incidence of PE was 5.7%. The incidence of PE is significantly higher with trauma-associated amputation than with extremity long-bone fracture without amputation. Bilateral amputations, multiple long-bone fractures, and pelvic fractures are independent risk factors for the development of PE. The use of aggressive prophylaxis, deep venous thrombosis screening with ultrasound, and use of prophylactic inferior vena cava filters should be considered in this patient population.

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Cited by 23 publications
(22 citation statements)
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“…In the military setting, Hutchison et al, and Gillern et al, both reported bilateral lower extremity fracture as a significant risk factor for VTE development [4,8]. Hutchison identified the highest risk for VTE to be multiple-limb amputations and above-knee amputations.…”
Section: Risk Factors For the Development Of Venous Thromboembolismmentioning
confidence: 99%
See 1 more Smart Citation
“…In the military setting, Hutchison et al, and Gillern et al, both reported bilateral lower extremity fracture as a significant risk factor for VTE development [4,8]. Hutchison identified the highest risk for VTE to be multiple-limb amputations and above-knee amputations.…”
Section: Risk Factors For the Development Of Venous Thromboembolismmentioning
confidence: 99%
“…In 2011, Gillern et al utilized retrospective data from the National Naval Medical Center (NNMC) [Bethesda, Maryland] Combat Trauma Registry to specifically evaluate casualties with wartime extremity injuries and included patients who (1) underwent at least one orthopedic procedure performed upon arrival to the USA or (2) sustained amputation before arrival [8]. In this group of 263 patients treated from March 2003-December 2007, 15 patients were diagnosed with DVT (5.7 %) and 15 with PE (5.7 %).…”
Section: Civilian Versus Combat Post-trauma Venous Thromboembolism Ratesmentioning
confidence: 99%
“…To our knowledge, the present study includes the largest retrospective analysis of combat upper limb amputation and thromboembolic disease . Nearly 20% of patients with AE amputation had DVT/PE.…”
Section: Discussionmentioning
confidence: 99%
“…Freedom and Enduring Freedom (OIF/OEF) have been characterized by wounds caused predominantly by ballistic and blast mechanisms of injury [1][2][3][4][5][6][7][8][9][10][11]. These wounds consist of massive soft tissue and orthopedic injuries secondary to the following mechanisms: damage due to pressure waves and forces exerted on bodily tissues, penetrating trauma, contamination with environmental particulates, burnrelated tissue destruction and blunt trauma from being 'thrown' by the explosion force [12].…”
Section: The Military Engagements In Operations Iraqimentioning
confidence: 99%