Incidence of second primary cancers in North Portugal—a population-based study

Abstract

SPC constitute an important dimension of the burden of cancer survivorship, and this needs to be taken into account when defining strategies for surveillance, prevention and counselling.

Risk of second primary cancers among patients with a first primary gastric cancer: A population-based study in North Portugal

“…gastric cancer patients were also the colon and rectum [10]; however, it did not show a significant risk of SPCs diagnosed more than two or 12 months after the gastric FPC [36]. In the present study, because of the larger sample size and longer follow-up period, we observed a significant increased risk of SPC after two months in males and though our estimate for SPCs defined using a 12 month gap was not statistically significant, it was more precise.…”

Incidence and relative risk of metachronous second primary cancers for 16 cancer sites, Osaka, Japan, 2000–2015: Population‐based analysis

“…7 Several studies in high-income countries have reported that cancer survivors are at higher risk of subsequent diagnosis with another cancer relative to the general population. [2][3][4][8][9][10][11] While the extent of such associations varies depending on the types of the first and second cancers, strong associations are seen between lifestyle-related (e.g. smoking and alcohol consumption) cancers.…”

“…Developing multiple primary cancers has become a common rather than rare event that patients and clinicians encounter. 1 , 2 , 3 , 4 Of all cancer survivors, the incidence of multiple primaries is reported to be in the range of 2%–17%. 1 , 2 , 3 , 4 , 5 In our previous assessments in Osaka, Japan, 2.0% of cancer survivors developed a second primary cancer within 10 years of first diagnosis during 1966–1989, 6 and this proportion rose nearly double (3.8%) by 1985–2005.…”

An unusual case of metachronous ascending colon and breast malignancy.

“…Another study by Tabuchi et al [4] reported that the incidence of metachronous malignancies has almost doubled over the last two decades. Pacheco-Figueiredo et al [5] concluded that the incidence of malignancies is higher in cancer survivors than the general population. The International agencies for research on cancer define multiple primary cancers as those cancers that originally developed in an organ or tissue and are not an extension, recurrence or metastasis.…”