Incidence of seropositivity to bordetella pertussis and mycoplasma pneumoniae infection in patients with chronic laryngotracheitis

Beaver, Mary Es; Karow, Colleen M.

doi:10.1002/lary.20535

Cited by 8 publications

(10 citation statements)

References 9 publications

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“…[2] Other etiologies of chronic laryngeal inflammation, such as allergies, inhaled irritants, and upper respiratory infections can cause signs and symptoms of laryngeal inflammation. [3] The prevalence of GERD in the United States is 10-20% as defined by weekly heartburn or acid regurgitation. [4] Selfreported symptoms of GERD do not correlate well with presence of pathologic reflux on objective testing.…”

Section: Original Articlementioning

confidence: 99%

Clinical utility of 24 hour pharyngeal pH monitoring for hoarseness

Beaver¹,

Karow

2012

J Laryngol Voice

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Objective: To evaluate the contribution of 24 hour pharyngeal pH monitoring of patient presenting with symptoms of hoarseness, globus, throat clearing, and sore throat. Study Design: Retrospective case study. Setting: Tertiary laryngology practice. Materials and Methods: Results of 167 pharyngeal pH studies performed for complaints of hoarseness, globus, and throat clearing in an outpatient private practice setting from 5/09-12/09 were analyzed for pharyngeal reflux pattern and severity. Patient records were reviewed for chief complaint, symptom duration, ten item Voice Handicap Index (VHI-10) and Reflux Symptom Index (RSI) scores. Nonparametric testing was used to compare symptom duration, VHI-10 scores, and RSI scores between those patients with and without abnormal pharyngeal pH studies. Results: 71 studies (43%) were normal with zero events below pH 5.5. 32 studies (19%), or 33% of all positive studies showed supine pharyngeal reflux only. 46 studies or 48% of all positive studies showed combination upright daytime reflux events and supine reflux. 18 studies or 19% of all positive studies had only upright events. There was no significant difference in presenting symptoms, symptom duration, or severity scores in the patients that had negative vs. positive pharyngeal pH studies. Conclusion: 24 hour pharyngeal pH study eliminates the diagnosis of reflux in a significant percentage of patients with hoarseness. Severity or duration of symptoms of hoarseness, globus, or throat clearing does not reliably predict presence of reflux.

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Section: Original Articlementioning

confidence: 99%

Clinical utility of 24 hour pharyngeal pH monitoring for hoarseness

Beaver¹,

Karow

2012

J Laryngol Voice

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“…Mycoplasma pneumoniae was not found to be a significant etiological agent for chronic pharyngitis in this study. Beaver and Karow 6 demonstrated that 15% of patients with chronic pharyngitis had elevated IgM to M pneumoniae . They also inferred that individuals with allergies and silent laryngopharyngeal reflux have a more fragile pharyngeal mucosa and are consequently more prone to infection with Chlamydia 6 .…”

Section: Discussionmentioning

confidence: 99%

Chronic Pharyngitis: Role of Atypical Organisms

Naina

Anandan

Mathews

et al. 2012

Otolaryngol.--head neck surg.

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“…Nevertheless, postmortem studies confirm the key role of the trachea in the natural history of pertussis [50]. The authors of a prospective study reported that among 54 adults presenting with chronic laryngotracheitis, 24% had elevated IgA and IgG levels and 15% had elevated anti-toxin pertussis IgM levels [51].…”

Section: Tracheal Infection During Pertussismentioning

confidence: 98%

Update on childhood and adult infectious tracheitis

Blot

Bonniaud-Blot²,

Favrolt

et al. 2017

Médecine et Maladies Infectieuses

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The trachea is a pivotal organ of the respiratory tract. Rather than a genuine anatomic border, it acts as a crossroad in all respiratory infectious processes. Even though not strictly limited to the trachea, infections such as laryngotracheitis and tracheobronchitis are frequently diagnosed in children, in particular during the winter season. Infectious tracheitis etiologies are diverse and the distinction between viral and bacterial origins, albeit difficult, remains relevant considering the substantial differences in terms of gravity and therapeutic management. This literature review summarizes the microbiological and clinical aspects of community-acquired and nosocomial tracheitis in adults and children, as well as the adequate diagnostic and therapeutic approaches. It also highlights the emergence of fungal tracheitis in immunocompromised patients, of ventilator-associated tracheitis in intensive care medicine, and beyond all that the potential short and long-term consequences of tracheitis.

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Incidence of seropositivity to bordetella pertussis and mycoplasma pneumoniae infection in patients with chronic laryngotracheitis

Cited by 8 publications

References 9 publications

Clinical utility of 24 hour pharyngeal pH monitoring for hoarseness

Clinical utility of 24 hour pharyngeal pH monitoring for hoarseness

Chronic Pharyngitis: Role of Atypical Organisms

Update on childhood and adult infectious tracheitis

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