Incidence of Skull Base and Orbital Erosion in Allergic Fungal Rhinosinusitis (AFRS) and Non‐AFRS

Ghegan, Mark D.; Lee, Fu‐Shing; Schlosser, Rodney J.

doi:10.1016/j.otohns.2005.11.025

Cited by 89 publications

(88 citation statements)

References 8 publications

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“…6 The potential of allergic fungal sinusitis to cause bone erosion is well established, with a 12-fold greater likelihood of such patients having bone erosion, compared with non-allergic fungal sinusitis patients. 15 Such bone erosion has been thought to be primarily caused by persistent pressure, and also by hyperaemia and inflammation of the surrounding mucosa. Incipient infiltration of the mucosa by fungal elements and consequent granulomatous reaction has also been noted.…”

Section: Discussionmentioning

confidence: 99%

Optic nerve compression in allergic fungal sinusitis

et al. 2011

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Section: Discussionmentioning

confidence: 99%

Optic nerve compression in allergic fungal sinusitis

et al. 2011

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“…Substantial involvement of the skull base and lamina papyracea occurs in up to 50% of cases. 1065,1066 The role of gender and ethnicity is unclear, but African-American males have been reported to have a higher incidence of erosion. 1067 Compressive noninfective optic neuropathy with visual loss is less common (about 4%) but can also occur, with the possibility of partial or complete recovery of vision.…”

Section: Viiif Crswnp: Complicationsmentioning

confidence: 99%

“…Characteristic CT scan findings include increased density of material within sinus cavities and expansion or erosion of paranasal sinus bony walls. Unlike CRSwNP, greater than 30% of AFRS patients have skull-base or orbital expansion/erosion on presentation, 1066,1077,1082,[1085][1086][1087][1088] potentially causing visual disturbance or facial deformity. 1070,1072,1083 Compared to CRSwNP overall, AFRS patients are younger, atopic, and often have unilateral disease.…”

Section: Viiig Crswnp and Afrs: Differences In Pathophysiologymentioning

confidence: 99%

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Orlandi

Kingdom

Hwang

et al. 2016

Int Forum Allergy Rhinol

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Background:The body of knowledge regarding rhinosinusitis (RS) continues to expand, with rapid growth in number of publications, yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS). Methods:Evidence-based reviews with recommendations (EBRRs) were developed for scores of topics, using previously reported methodology. Where existing evidence was insufficient for an EBRR, an evidence-based review (EBR) was produced. The sections were then synthesized and the entire manuscript was then reviewed by all authors for consensus. Results:The resulting ICAR:RS document addresses multiple topics in RS, including acute RS (ARS), chronic RS (CRS) with and without nasal polyps (CRSwNP and CRSsNP), recurrent acute RS (RARS), acute exacerbation of CRS (AE-CRS), and pediatric RS. Conclusion:As a critical review of the RS literature, ICAR:RS provides a thorough review of pathophysiology and evidence-based recommendations for medical and surgical treatment. It also demonstrates the significant gaps in our understanding of the pathophysiology and optimal management of RS. Too o en the foundation upon which these recommendations are based is comprised of lowerlevel evidence. It is our hope that this summary of the evidence in RS will point out where additional research efforts may be directed. C 2016 ARS-AAOA, LLC. Key Words:rhinosinusitis; chronic rhinosinusitis; acute rhinosinusitis; recurrent acute rhinosinusitis; evidence-based medicine; systematic review; endoscopic sinus surgery List of Abbreviations Used

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“…The disease's course is typically indolent and non-aggressive; however, as allergic mucin accumulates within the paranasal sinuses, it may form a mucocele and mimic an invasive process. In 6-56% of patients with AFRS, the expanding mass leads to bony erosion and involvement of adjacent structures [5]. However, investigators soon noted that in some cases, the allergic mucin evacuated from the sinuses did not have identifiable fungal elements; these patients were labeled as having an ''AFRS-like syndrome'' [6].…”

Section: Introductionmentioning

confidence: 99%