Incidence of Stomach and Esophageal Cancers in Mongolia: Data from 2009 to 2018

Lonjid, Tulgaa; Tsegmed, Sambuu; Tumurbat, Nasanjargal; Banzragch, Ulziisaikhan; Dondov, Ganchimeg; Badamjav, Tegshjargal; Davaa, Bayar; Tudev, Bolor-Erdene; Batsaikhan, Batbold

doi:10.5005/jp-journals-10018-1313

Cited by 4 publications

(2 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Over the last 30 years, stomach cancer, esophageal cancer, and lung cancer remains the leading causes of death. Mongolia has a high prevalence of Helicobacter pylori infection, with approximately 70% of patients suffering from gastric problem [ 17 ], which significantly increases the risk of stomach cancer [ 18 ]. In addition to the risk factors mentioned above, traditional hot tea and meals, a high consumption of red meat [ 17 ], re-heated meals prepared the day before and reheated the next day may be considered common risk behavior among Mongolians, which may also contribute to stomach cancer.…”

Section: Discussionmentioning

confidence: 99%

Mongolia health situation: based on the Global Burden of Disease Study 2019

Chimed‐Ochir

Delgermaa²,

Takahashi

et al. 2022

BMC Public Health

View full text Add to dashboard Cite

Background Over the past few decades, economic, political, and social changes have directly and indirectly affected the health of the Mongolian population. To date, no comprehensive analysis has been conducted on the burden of diseases in this country. Thus, we aimed to describe the leading causes of death and disabling conditions and their trends between 1990 and 2019 in the Mongolian population. Methods We used the data from the Global Burden of Disease (GBD) 2019 study. In the current study, we examined life expectancy at birth, healthy life expectancy, the 20 leading causes of death, years of life lost (YLLs), years lived with disability (YLDs), disability-adjusted-life-years (DALYs), and the contribution of major risk factors to DALYs in Mongolia. Findings The life expectancy at birth in Mongolia has gradually increased since 1995 and reached 63.8 years for men and 72.7 for women in 2019. The highest increase in the age-standardised death rate between 1990 and 2019 occurred in alcohol use disorders (628.6%; 95% UI 10.0–1109.6) among men, and in liver cancer (129.1%; UI 65.3–222.4) among women. Ischaemic heart disease and stroke showed the highest rates of death, YLLs, and DALYs among both men and women. In 2019, the highest age-standardised rates of DALYs were attributable to high systolic blood pressure and dietary risks. Interpretation Although Mongolia saw substantial improvements across many communicable diseases, maternal and neonatal disorders, and under-5 mortality between 1990 and 2019, non-communicable diseases remained leading causes of mortality. The mortality from the most preventable causes such as injury, alcohol use, and dietary risks remain substantially high, suggesting that individual and social efforts are needed to tackle these diseases. Our analyses will support the development of policy priorities and action plans in multiple sectors to improve the overall health of the Mongolian population. Funding Bill & Melinda Gates Foundation.

show abstract

Section: Discussionmentioning

confidence: 99%

Mongolia health situation: based on the Global Burden of Disease Study 2019

Chimed‐Ochir

Delgermaa²,

Takahashi

et al. 2022

BMC Public Health

View full text Add to dashboard Cite

show abstract

“…Therefore, national screening program should be continuous. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24…”

mentioning

confidence: 99%

Initial results of screening program in Mongolia where burdening high gastric cancer – Multi center study

Jargalsaikhan,

Boldbaatar,

Khurelbaatar

et al. 2024

Endoscopy

View full text Add to dashboard Cite

Diagnostic performances of pepsinogens and gastrin-17 for atrophic gastritis and gastric cancer in Mongolian subjects

Dondov

Amarbayasgalan²,

Batsaikhan³

et al. 2022

PLoS ONE

Self Cite

View full text Add to dashboard Cite

In Mongolia, gastric cancer morbidity and mortality are high, and more than 80 percent of cases are diagnosed at an advanced stage. This study aimed to evaluate pepsinogens (PGIs) and gastrin-17 (G-17) levels and to determine the diagnostic performances for gastric cancer and chronic atrophic gastritis among Mongolian individuals. We enrolled a total of 120 subjects, including gastric cancer (40), atrophic gastritis (40), and healthy control (40), matched by age (±2) and sex. Pepsinogen I (PGI), Pepsinogen II (PGII), G-17, and H. pylori IgG levels were measured using GastroPanel ELISA kit (Biohit, Helsinki, Finland). Also, PGI to PGII ratio (PGR) was calculated. For atrophic gastritis, when the optimal cut-off value of PGI was ≤75.07 ng/ml, the sensitivity and specificity were 75% and 50%, respectively; when the optimal cut-off value of PGR was ≤6.25, sensitivity and specificity were 85% and 44.7%, respectively. For gastric cancer, when the optimal cut-off value of PGI was ≤35.25 ng/ml, the sensitivity and specificity were 47.2% and 86.8%, respectively; when the optimal cut-off value of PGR was ≤5.27, sensitivity and specificity were 75% and 60.5%, respectively. Combinations of biomarkers with risk factors could improve diagnostic accuracy (AUC for atrophic gastritis 74.8, 95% CI 64.0–85.7, p<0.001; AUC for gastric cancer 75.5, 95% CI 64.2–86.8, p<0.001). PGI, PGR biomarkers combined with the risk of age, family history of gastric cancer, and previous gastric disease could not be an alternative test for upper endoscopy but might be a supportive method which is identifying individuals at medium- and high risk of gastric cancer and precancerous lesions who may need upper endoscopy.

show abstract

Incidence of Stomach and Esophageal Cancers in Mongolia: Data from 2009 to 2018

Cited by 4 publications

References 19 publications

Mongolia health situation: based on the Global Burden of Disease Study 2019

Mongolia health situation: based on the Global Burden of Disease Study 2019

Initial results of screening program in Mongolia where burdening high gastric cancer – Multi center study

Diagnostic performances of pepsinogens and gastrin-17 for atrophic gastritis and gastric cancer in Mongolian subjects

Contact Info

Product

Resources

About