Incidence of type 1 diabetes mellitus in Navarre stabilized in the last eight years

Forga, Luis; Tamayo, Ibai; Chueca, M.; Ibáñez, Berta; Terreros, Amaya Sainz de los; Goñi, Mabel

doi:10.1016/j.endien.2018.05.004

Cited by 2 publications

(2 citation statements)

References 27 publications

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“…For five (38%) studies, including data from Serbia ( 9 ), Sweden (Diabetes Incidence Study in Sweden [DISS]) ( 10 ), Korea ( 11 ), Taiwan ( 12 ), and the U.S. ( 13 ), a decrease was reported in adult-onset T1D incidence over time, ranging from 1983 to 2017. In contrast, in one study from Mali ( 14 ) an increase was reported in adult-onset T1D incidence between 2007 and 2016, while data from Spain (2009–2016) ( 15 ), the U.K. (1994–2013) ( 16 ), and Hong Kong (2002–2015) ( 17 ) showed no change over time. These trends were consistent across age-groups.…”

Section: Resultsmentioning

confidence: 89%

“…Among all studies, seven (15%) included use of biomarkers (in conjunction with clinical features) for definition of T1D. These studies were from the U.K. (UK Biobank) ( 22 ), Sweden ( 10 , 20 , 23 ), the U.S. (California) ( 24 ), Spain (Navarre) ( 15 ), and Norway (Nord-Trøndelag Health Study [The HUNT Study]) ( 25 ). (See Supplementary Table 5 for detailed description of T1D definition and Supplementary Table 6 for scores related to diagnosis of T1D.)…”

Section: Resultsmentioning

confidence: 99%

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The Incidence of Adult-Onset Type 1 Diabetes: A Systematic Review From 32 Countries and Regions

et al. 2022

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BACKGROUND The epidemiology of adult-onset type 1 diabetes (T1D) incidence is not well-characterized due to the historic focus on T1D as a childhood-onset disease. PURPOSE We assess the incidence of adult-onset (≥20 years) T1D, by country, from available data. DATA SOURCES A systematic review of MEDLINE, Embase, and the gray literature, through 11 May 2021, was undertaken. STUDY SELECTION We included all population-based studies reporting on adult-onset T1D incidence and published from 1990 onward in English. DATA EXTRACTION With the search we identified 1,374 references of which 46 were included for data extraction. Estimates of annual T1D incidence were allocated into broad age categories (20–39, 40–59, ≥60, or ≥20 years) as appropriate. DATA SYNTHESIS Overall, we observed the following patterns: 1) there is a paucity of data, particularly in low- and middle-income countries; 2) the incidence of adult-onset T1D is lowest in Asian and highest in Nordic countries; 3) adult-onset T1D is higher in men versus women; 4) it is unclear whether adult-onset T1D incidence declines with increasing age; and 5) it is unclear whether incidence of adult-onset T1D has changed over time. LIMITATIONS Results are generalizable to high-income countries, and misclassification of diabetes type cannot be ruled out. CONCLUSIONS From available data, this systematic review suggests that the incidence of T1D in adulthood is substantial and highlights the pressing need to better distinguish T1D from T2D in adults so that we may better assess and respond to the true burden of T1D in adults.

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