Incidence of upper tract urothelial carcinoma in Spain

Aparicio, Tomás Fernández; Llopis, J.A. Galán; Alcaide, R. Cansino; Delgado, Manuel; Álvarez-Ossorio, J.L.

doi:10.1016/j.acuroe.2020.03.003

Cited by 2 publications

(3 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of the studies from Asia, seven (47%) were conducted in Taiwan. Nearly all studies employed a retrospective cohort study design except for two studies: Mok et al and Aparicio et al, which were prospective cohort studies [12,13]. Similarly, nearly all studies focused on the incidence of UTUC, with only one study by Visser and colleagues [14] reporting incidence together with prevalence.…”

Section: Resultsmentioning

confidence: 99%

“…Mok et al [12] reported a higher incidence of ureter cancer in patients with a low estimated glomerular filtration rate (eGFR) of < 45 (13.7 per 10,000 personyears) compared to patients with a higher eGFR of ≥ 90 (0.3). The second study by Aparicio et al [13] was a multicentre study of 31 institutions in Spain utilising a centralised database to report cases of UTUC prospectively. This study reported a relatively high incidence rate of 3.27 (95% CI 2.93-3.61) per 100,000 person-years, which the authors conclude is due to the prospective nature of their study.…”

Section: Prospective Cohort Studiesmentioning

confidence: 99%

See 1 more Smart Citation

The incidence and prevalence of upper tract urothelial carcinoma: a systematic review

et al. 2021

View full text Add to dashboard Cite

Background Upper tract urothelial carcinoma (UTUC) is a rare urological cancer that is still an important public health concern in many areas around the world. Although UTUC has been linked to a number of risk factors, to our knowledge no systematic review has been published on the overall incidence and prevalence of de-novo UTUC. This review aimed to examine the global epidemiology of UTUC to provide clinicians and public health specialists a better understanding of UTUC. Methods A systematic search was conducted on MEDLINE, Embase, and the Web of Science using a detailed search strategy. Observational epidemiological studies describing the incidence and prevalence of de-novo UTUC in adults were included, and the Joanna Briggs Institute checklist was used for critical appraisal and data extraction of the studies selected. Results The systematic search identified 3506 papers, of which 59 papers were included for qualitative synthesis. The studies selected included data ranging from the years 1943 to 2018. A comprehensive qualitative synthesis of the data was performed. UTUC incidence generally varied according to age (higher with increasing age), sex (unclear), race (unclear), calendar time (increased, stable, or decreased according to region), geographical region (higher in Asian countries), occupation (higher in seamen and printers), and other population characteristics. Prevalence was only reported by one study, which showed UTUC to have the highest incidence of the rare urogenital cancers in Europe. Conclusion This systematic review highlights an increased incidence of UTUC in certain groups, including increasing age and certain occupations such as seamen. The incidence of UTUC also varies between certain geographical regions. The trend of UTUC incidence for sex, race, and calendar time is less clear due to a wide variety of metrics used by the studies identified. More studies are also required on the prevalence of UTUC to understand its disease burden. Trial registration This review was registered on PROSPERO (registration number CRD42019134255).

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Prospective Cohort Studiesmentioning

confidence: 99%

The incidence and prevalence of upper tract urothelial carcinoma: a systematic review

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Scandinavian countries including Denmark (21,22), Norway (2), Iceland (23), and The Netherlands (24) have all contributed to the UTUC literature utilising large cancer and admission based registries. Other European nations have also utilised registry based data to contribute to their understanding of UTUC including Spain (25), Croatia (26), and The United Kingdom via the National Cancer Repository (27). There have also been joint efforts to understand rare cancers such as UTUC in multinational collaborations (28).…”

Section: International General Registriesmentioning

confidence: 99%

The utility of clinical registries for guiding clinical practice in upper tract urothelial cancer: a narrative review

Kealey¹,

Snider²,

Hayne³

et al. 2023

Transl Androl Urol

View full text Add to dashboard Cite

Background and Objective: Upper tract urothelial cancer (UTUC) lacks high-quality evidence to appraise current patterns of presentation, diagnosis, treatment and outcomes as a result of disease rarity and patient heterogeneity. Registries may overcome many of the challenges making clinical trials challenging in UTUC and provide answers to many of the clinical questions that afflict UTUC management. In this narrative review we aim to summarise the design of registries that have contributed to the UTUC literature, discuss their strengths and limitations and the future directions of registries in UTUC.Methods: Two independent reviewers conducted a search of the OVID MEDLINE database from July 2002-July 2022. Included articles were required to be published in peer reviewed journals and use registrybased methodology to report on UTUC. Search was limited by MeSH and key words and was limited to the English language.Key Content and Findings: One hundred and forty-four articles were identified and included as reporting on UTUC from a registry-based methodology. Articles utilising registry-based data have substantially increased over the study period with the majority of articles arising from large generalised cancer databases in North America. There has been an increase in UTUC-specific registries in the previous five years that have offered the most granular, complete analysis and these will continue to report in the coming years. The majority of published data assessed epidemiological factors and compared outcomes of treatment modalities with a small proportion of articles focusing on prognostic nomograms and quality of life. Larger cancer registries that contribute the majority of the published analysis are likely subject to significant selection bias when comparing cohorts for treatment analysis and the need for prospective UTUC specific registries is apparent. Future directions include the potential for registry-based randomised controlled trials (RCTs) and clinical quality registries (CQR) that have the ability to change practice and improve care. Conclusions:The utilisation of registry-based methodology for analysis in UTUC has increased substantially over the last 20 years. In addition to the utilisation of large cancer registries, the creation of UTUC specific registries is likely to contribute the most granular, translatable data in diagnosis and management.

show abstract

Incidence of upper tract urothelial carcinoma in Spain

Cited by 2 publications

References 14 publications

The incidence and prevalence of upper tract urothelial carcinoma: a systematic review

The incidence and prevalence of upper tract urothelial carcinoma: a systematic review

The utility of clinical registries for guiding clinical practice in upper tract urothelial cancer: a narrative review

Contact Info

Product

Resources

About