Incidence of Urinary Tract Infections (UTI) amongst Patients Attending Primary Health Centres in Anambra State

Ogbukagu, Chioma M.; Anakwenze, Vivian Nonye; Ekwealor, C. C.; Ezemba, Chinyere Constance; Ekwealor, I. A.

doi:10.4236/aim.2016.67054

Cited by 12 publications

(10 citation statements)

References 20 publications

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“…The observations with gram-negative bacteria have the highest sensitivity to Gentamycin after nitrofurantoin made by Kenechukwu et al 40 are in line with our findings. Gentamycin is an aminoglycoside antibiotic that works by inhibiting protein synthesis, thereby preventing bacteria survival and multiplication.…”

Section: Discussionsupporting

confidence: 82%

Asymptomatic UTI in pregnancy attending at tertiary care of Nepal

Yadav

2018

Int J Res Med Sci

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Background: Urinary tract infections (UTI) during pregnancy issued by improper laboratory investigations situate women at risk of several detrimental complications. Untreated asymptomatic UTI (AUTI) may lead to pyelonephritis preterm birth, low birth weight, etc. Urine culture is used to confirm the diagnosis of UTI. Aim of this research was to carry out to find the prevalence of asymptomatic UTI and to establish antimicrobial drug susceptibility of the pathogens resulting asymptomatic UTI in pregnant women attending at tertiary care, Nepal.Methods: The urine samples were collected by mid-stream clean catch method from 600 pregnant women of age 15-45 years (mean age – 28.84 years) visiting for antenatal check up in the Department of Gynaecology and Obstetrics, Chitwan Medical College (CMC), a tertiary care of Nepal. All the urine samples were subjected to bio-physical, biochemical, microscopic, and microbiological analysis. The prevalence of UTI in three trimesters and in different age groups was obtained together with antimicrobial drug susceptibility tests.Results: On overall l51.83% of urine samples revealed with significant bacteriuria considered as the AUTI. On One- way ANOVA test, there was significant (P< 0.045) prevalence of AUTI when compared among different trimesters, though higher prevalence being in the first (40%) and second (45.33%) trimesters. The prevalence of AUTI was significant (P<0.004) among different age groups of the pregnancy. However, the most affectecd age groups were between 21-29 years. Escherichia coli were the most implicated organism (67.8%) followed by Klebsiella pneumonia (21.6%). The gram-negative bacteria (E. coli, K. pneumonia, and K. oxytoca) were more sensitive against Amikacin, Gentamycin, Meropenem, and Nitrofurantointhan. Other drugs whereas; gram positive bacteria (E. feacalis) had high susceptibility with Vancomycin.Conclusions: There was high incidence of AUTI among the pregnant ladies in the study region; therefore, microbial screening of urine of all pregnant women are must and should be included in the routine antenatal checkups to detect the AUTI to cut down and prevent the maternal and obstetric detrimental complications in them.

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Section: Discussionsupporting

confidence: 82%

Asymptomatic UTI in pregnancy attending at tertiary care of Nepal

Yadav

2018

Int J Res Med Sci

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“…They observed that all strains tested were susceptible to chloramphenicol. Contrary to our result [49], reported high resistance of Escherichia coli to antibiotics. However [50], noted that bacterial isolates from fish ponds were most susceptible to erythromycin.…”

Section: Discussioncontrasting

confidence: 99%

Physicochemical and Antibacterial Susceptibility Profile of Fish Pond Waters in Anambra State, Nigeria

Ogbukagu¹,

Anaukwu²,

Ekwealor³

et al. 2020

AJMR

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“…(96/284). This study had high prevalence compared to studies conducted at Dessie (22.7%) [11], Rwanda (19.3%) [12], and Nigeria (17.6%) [13] Prevalence of ESBLs producers within the Enterobacteriaceae in the study was 41.7%. This finding is consistent with similar studies carried out at Jimma University Specialized Hospital (38.4%) [14], in Addis Ababa (50.7%) [15], in Nigeria (47.1%) [16] and in India (38.2%) [17].…”

Section: Discussionmentioning

confidence: 54%

Isolation of extended spectrum beta-lactamase producing Enterobacteriaceae among children with urinary tract infection: A cross sectional study.

Agegnehu¹,

Worku²,

Nigussie³

et al. 2020

Preprint

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Background: Resistance of Gram-negative bacteria to antibiotics had increased at an alarming pace over the last two decades. Empirical antibiotic treatment of UTI practice created opportunity for frequent use of antibiotics that resulted in emergence of resistant strains. Extended spectrum beta-lactamase producing Enterobacteriaceae are emerging worldwide and are usually multi-drug resistant; thus, limiting treatment options for these organisms. Hence, it is mandatory to scrutinize the extent of the problem in the study area. Objective: We investigated the prevalence and correlates of extended spectrum beta-lactamase producing Enterobacteriaceae and their antibacterial resistance profile among children with urinary tract infection (UTI) at Hawassa University Comprehensive Specialized Hospital. Method: A hospital-based cross sectional study was conducted from February 1-July 30/ 2018. A semi-structured questionnaire was used to collect data from 284 children suspected of UTI. Bacterial species were isolated using standard bacteriological techniques. Antibiotic susceptibility testing was done using Kirby-Bauer disk diffusion method and ESBL production was detected by double disc synergy test. Data entry, cleaning and statistical analysis was done using SPSS version 20. Results: Overall, Enterobacteriaceae accounted for 75% (72/96) of UTI infections. The most frequent Enterobacteriaceae were E. coli , 44.4% (32/72) and K. pneumoniae , 27.8% (20/72). Overall, ESBL-producers within Enterobacteriaceae accounted for 41.7% (30/72) and magnitude of multi-drug resistance level was 86.1% (62/72). ESBL producing K. pneumoniae and E. coli accounted for 70% (14/20) and 37.5% (12/32), respectively of all the respective isolates. Previous UTI within the past 12 month (AOR= 0.08, 95% CI (0.01-0.57) and medium family wealth index (AOR = 0.03, 95% CI (0.00-0.27) were associated with infection of ESBL-producing Enterobacteriaceae . Conclusion: ESBL producing Enterobacteriaceae were prevalent among UTI cases; where E. coli and K. pneumoniae were the major isolated resistant strains that contributed mainly to the problem. Majority of Enterobacteriaceae isolated were resistant to commonly prescribed drugs. Key words : ESBL, Antimicrobial Resistance, UTI, Children.

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Incidence of Urinary Tract Infections (UTI) amongst Patients Attending Primary Health Centres in Anambra State

Cited by 12 publications

References 20 publications

Asymptomatic UTI in pregnancy attending at tertiary care of Nepal

Asymptomatic UTI in pregnancy attending at tertiary care of Nepal

Physicochemical and Antibacterial Susceptibility Profile of Fish Pond Waters in Anambra State, Nigeria

Isolation of extended spectrum beta-lactamase producing Enterobacteriaceae among children with urinary tract infection: A cross sectional study.

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