Incidence, predictors, and outcomes of high-degree atrioventricular block complicating acute myocardial infarction treated with thrombolytic therapy

Meine, Trip J.; Al‐Khatib, Sana M.; Alexander, John H.; Granger, Christopher B.; White, Harvey D.; Kilaru, Rakhi; Williams, Kathryn; Ohman, E. Magnus; Topol, Eric J.; Califf, Robert M.

doi:10.1016/j.ahj.2004.07.035

Cited by 99 publications

(67 citation statements)

References 17 publications

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“…As to clinical variables, the patients older than 65 years have higher risk of CAVB development. Similarly, Meine et al [20] reported that significant independent predictors of AV block are inferior MI, older age, worse Killip class at presentation, female sex, current smoking, hypertension, and diabetes. The prevalence of stenosis in LAD was much higher in the patients with CAVB.…”

Section: Discussionmentioning

confidence: 90%

“…Conduction defects complicated acute MI have a graded impact on short-term prognosis [3,[17][18][19][20][21]. Although Chen et al [22] showed that thrombolytic therapy can reduce the incidence of severe AV block, shorten its duration and decrease mortality, Ben Ameur et al [23] noted that thrombolysis does not affect the incidence of AV block but improves the outcomes of these patients.…”

Section: Discussionmentioning

confidence: 99%

“…In our study, CAVB was shown to increase in-hospital mortality by 6.8 folds independent to the thrombolytic therapy. A number of studies have assessed the in-hospital significance of AV block in acute inferior MI [1][2][3][4][20][21][22][23][24]. In-hospital mortality rates are varying from 8 to 45% [1][2][3][4][20][21][22][23][24].…”

Section: Discussionmentioning

confidence: 99%

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N-terminal pro-brain natriuretic peptide and electrocardiographic variables associated with increased risk of complete atrioventricular block and mortality in patients with acute inferior myocardial infarction

Geyık

Özdemir²,

Osmonov³

et al. 2012

Cardiol J

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Background: Although brain natriuretic peptide (BNP) levels are shown to be an important prognostic factor in patients with acute myocardial infarction (MI), the relationship between arrhythmias and BNP levels is not known. This study assessed whether baseline clinical factors, N-terminal-proBNP (NT-proBNP) levels and electrocardiographic patterns of acute inferior MI are associated with greater risk of developing complete atrioventricular block (CAVB) and mortality.

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Section: Discussionmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 99%

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N-terminal pro-brain natriuretic peptide and electrocardiographic variables associated with increased risk of complete atrioventricular block and mortality in patients with acute inferior myocardial infarction

Geyık

Özdemir²,

Osmonov³

et al. 2012

Cardiol J

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show abstract

“…If associated with hemodynamic compromise it should be treated. AV block: Data from four large, randomized trials suggest that AV block occurs in almost 7% (Meine et al, 2005) and persistent LBBB in up to 5.3% of cases of STEMI (Newby et al, 1996). Patients with peri-infarction AV block have an higher in hospital mortality than those with preserved AV conduction (Meine et al, 2005).…”

Section: Sinus Bradycardia and Heart Blockmentioning

confidence: 99%

ECG in Acute Myocardial Infarction in the Reperfusion Era

Napodano¹,

Paganelli²

2012

Advances in Electrocardiograms - Clinical Applications

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“…High (second or third) degree AV block occurs in approximately 9.8 percent of patients with an inferior MI and 3.2 percent of patients with an anterior MI who receive thrombolytic therapy. 17 Mortality among patient with CHB is still high and has not declined within last decade. The AMI patients who develop CHB in the thrombolytic era have significantly worse prognosis than do patients without CHB.…”

mentioning

confidence: 99%

Multivessel primary PCI in patient with peripheral arterial disease

et al. 2017

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Thrombosis of multiple coronary arteries is extremely rare finding in the setting of acute myocardial infarction. This often leads to cardiogenic shock and sudden cardiac death. We report a case of 61 years old gentleman who presented with complaints of sudden onset of chest pain of 4hours duration and dizziness with near syncope 2 hours prior to presentation and ST segment elevation in anterior and inferior leads with complete heart block. Coronary angiogram revealed total occlusion of left anterior descending (LAD) and right coronary arteries (RCA). After the PCI to RCA follwed by LAD, patient went into Pulse less electrical activity. Cardiopulmonary resuscitation, immediate percutaneous coronary intervention of the LAD and RCA, temporary pacing, immediate intubation and mechanical ventilation was carried out. The patient was eventually discharged with a New York Heart Association functional class II heart failure.Nepalese Heart Journal 2017; 14(1): 35-38

show abstract

Incidence, predictors, and outcomes of high-degree atrioventricular block complicating acute myocardial infarction treated with thrombolytic therapy

Cited by 99 publications

References 17 publications

N-terminal pro-brain natriuretic peptide and electrocardiographic variables associated with increased risk of complete atrioventricular block and mortality in patients with acute inferior myocardial infarction

N-terminal pro-brain natriuretic peptide and electrocardiographic variables associated with increased risk of complete atrioventricular block and mortality in patients with acute inferior myocardial infarction

ECG in Acute Myocardial Infarction in the Reperfusion Era

Multivessel primary PCI in patient with peripheral arterial disease

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