Incidence, prevalence and mortality of kidney cancer in Spain: Estimates and projections for the 1998–2022 period

Souza, Dyego Leandro Bezerra de; Bernal, M.

doi:10.1016/j.acuroe.2011.09.005

Cited by 8 publications

(7 citation statements)

References 29 publications

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“…BMI was calculated (Quetelet index), which was defined according to the patient's weight in kilogram divided by their height in meter. 2 Patients were divided into 4 groups based on the recommendations from the World Health Organization (WHO) 14 and the clinical guidelines for obesity control in China, including underweight patients, less than 18.5 kg/m 2 , normal-weight patients from 18.5 kg/m 2 to 23.9 kg/m 2 , overweight patients between 24 kg/m 2 and 27.9 kg/m 2 and obese patients with 28 kg/m 2 or more. Pathological tumor size was mainly determined by imaging techniques.…”

Section: Patient Characteristicsmentioning

confidence: 97%

“…1 In Spain, a rapid upward trend in the incidence, mortality and prevalence of kidney cancer has also been observed in the last ten years. 2 Over the last few decades, new surgical techniques have been applied for the treatment of renal tumors, such as partial nephrectomy (PN) and laparoscopic surgery. Previous studies have shown that PN can provide equivalent oncologic control as for radical nephrectomy (RN) in renal tumors less than 4 cm in diameter, with the benefit of preserving renal function.…”

Section: Palabras Clavementioning

confidence: 99%

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Obesity, hypertension and diabetes mellitus affect complication rate of different nephrectomy techniques

Hua

Cheng

Zu-Jun

et al. 2014

Actas Urológicas Españolas (English Edition)

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Section: Patient Characteristicsmentioning

confidence: 97%

Section: Palabras Clavementioning

confidence: 99%

Obesity, hypertension and diabetes mellitus affect complication rate of different nephrectomy techniques

Hua

Cheng

Zu-Jun

et al. 2014

Actas Urológicas Españolas (English Edition)

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“…Renal tumours are amongst the most common neoplasms in the Western world, representing about 3% of all malignant tumours in adults . Consequently their clinical management represents a major concern for health services worldwide . The current WHO classification of renal cell carcinoma includes four main types; clear cell renal cell carcinoma (CCRCC), papillary renal cell carcinoma (PRCC), chromophobe renal cell carcinoma and collecting duct carcinomas, as well as unclassified renal cell carcinoma .…”

Section: Introductionmentioning

confidence: 99%

Targeted next‐generation sequencing and non‐coding RNA expression analysis of clear cell papillary renal cell carcinoma suggests distinct pathological mechanisms from other renal tumour subtypes

Lawrie

Larrea

Larrinaga

et al. 2013

The Journal of Pathology

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Clear cell tubulopapillary renal cell carcinoma (CCPRCC) is a recently described rare renal malignancy that displays characteristic gross, microscopic and immunohistochemical differences from other renal tumour types. However, CCPRCC remains a very poorly understood entity. We therefore sought to elucidate some of the molecular mechanisms involved in this neoplasm by carrying out targeted next-generation sequencing (NGS) to identify associated mutations, and in addition examined the expression of non-coding (nc) RNAs. We identified multiple somatic mutations in CCPRCC cases, including a recurrent [3/14 cases (21%)] non-synonymous T992I mutation in the MET proto-oncogene, a gene associated with epithelial-to-mesenchymal transition (EMT). Using a microarray approach, we found that the expression of mature (n = 1105) and pre-miRNAs (n = 1105), as well as snoRNA and scaRNAs (n = 2214), in CCPRCC cases differed from that of clear cell renal cell carcinoma (CCRCC) or papillary renal cell carcinoma (PRCC) tumours. Surprisingly, and unlike other renal tumour subtypes, we found that all five members of the miR-200 family were over-expressed in CCPRCC cases. As these miRNAs are intimately involved with EMT, we stained CCPRCC cases for E-cadherin, vimentin and β-catenin and found that the tumour cells of all cases were positive for all three markers, a combination rarely reported in other renal tumours that could have diagnostic implications. Taken together with the mutational analysis, these data suggest that EMT in CCPRCC tumour cells is incomplete or blocked, consistent with the indolent clinical course typical of this malignancy. In summary, as well as describing a novel pathological mechanism in renal carcinomas, this study adds to the mounting evidence that CCPRCC should be formally considered a distinct entity. Microarray data have been deposited in the GEO database [GEO accession number (GSE51554)].

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“…The highest incidence rate was found in Holland with values of 16.9 and 9.2 per 100000 population in males and females, respectively. The lowest incidence was 8.2 in males and 3.7 in females per 100000 population in Spain (9)(10)(11)(12). Falebita et al associated these findings with better diagnosis and registration (13).…”

Section: Introductionmentioning

confidence: 98%

Prevalence of Kidney, Renal Pelvis, and Ureter Cancers in Isfahan Province, Iran

Tolou-Ghamari

2019

J Arch Mil Med

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Background: According to the literature, the incidence of kidney cancer is on the rise worldwide. Objectives: The aim of this investigation was to provide the data of period prevalence of kidney, renal pelvis, and ureter cancers in the general population including the military or non-military population in Isfahan province, Iran. Methods: Data associated with cancers of the kidney, renal pelvis, and ureter were obtained from the Isfahan Cancer Registry between 2011 and 2015. Kidney, renal pelvis, and ureter cancers were defined by topography codes of C64, C65, and C66, respectively. Results: There were 404, 21, and 18 registered cases of kidney, renal pelvis, and ureter cancers, respectively, corresponding to a PP of 8.9 per 100000 population. The mean ± SD of age was 56.6 ± 16.8 years in patients. The age of kidney cancer patients was more than 50 years in 51% of the cases. The incidences were 2per 100000 population. The death data confirmed 14% and 86% mortality associated with kidney cancer and renal pelvis, respectively. Conclusions: The incidence rate of kidney cancer showed increases by 20%. The data confirmed high mortality associated with cancer of renal pelvis. In order to decrease cancer incidence, healthcare planning should be based on military management together with a well-structured pharmacotherapy strategy.

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Incidence, prevalence and mortality of kidney cancer in Spain: Estimates and projections for the 1998–2022 period

Cited by 8 publications

References 29 publications

Obesity, hypertension and diabetes mellitus affect complication rate of different nephrectomy techniques

Obesity, hypertension and diabetes mellitus affect complication rate of different nephrectomy techniques

Targeted next‐generation sequencing and non‐coding RNA expression analysis of clear cell papillary renal cell carcinoma suggests distinct pathological mechanisms from other renal tumour subtypes

Prevalence of Kidney, Renal Pelvis, and Ureter Cancers in Isfahan Province, Iran

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