Incidence, risk factors for amputation among patients with diabetic foot ulcer in a Chinese tertiary hospital

Li, Xiang; Xiao, Ting; Wang, Yuzhen; Gu, Heng; Liu, Zhiguo; Jiang, Yufeng; Liu, Yanjun; Lu, Zuqian; Yang, Xiaopin; Li, Yin; Zhang, Xu

doi:10.1016/j.diabres.2011.03.014

Cited by 68 publications

(68 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Meanwhile, HDL cholesterol levels might simply be a marker of nutritional status. A Chinese report showed that lower triglycerides levels were an independent risk factor for LEA in patients with DFUs [30]. However, in the present study, the association of HDL cholesterol levels with LEA or wound-related death were independent of serum albumin levels, and furthermore, neither triglycerides levels nor LDL cholesterol levels were a predictor of the endpoint, which suggests that HDL cholesterol levels may be more than a marker of nutritional status in patients with DFUs.…”

Section: Discussioncontrasting

confidence: 62%

HDL cholesterol as a predictor for the incidence of lower extremity amputation and wound-related death in patients with diabetic foot ulcers

et al. 2015

View full text Add to dashboard Cite

Section: Discussioncontrasting

confidence: 62%

HDL cholesterol as a predictor for the incidence of lower extremity amputation and wound-related death in patients with diabetic foot ulcers

et al. 2015

View full text Add to dashboard Cite

“…Correspondingly, while another study in Iran emphasized the correlation between patients’ gender and amputation (21), the current study could not confirm such an association. Such a correlation, however, was not reported by Li et al in their study on a population with a 21.8% rate of amputation in China (22). …”

Section: Discussionmentioning

confidence: 64%

Diabetic Foot: Infections and Outcomes in Iranian Admitted Patients

Azar

Ghiasi

Hajiabdolbaghi

et al. 2014

Jundishapur J Microbiol

View full text Add to dashboard Cite

Background:Diabetes mellitus (along with its complications) has become a global problem. Diabetic foot infection, among the most common complications, is responsible for 40 to 50% of foot amputations. Antibiotic-resistant microorganisms, however, have compromised empiric therapy in the infected patients.Objectives:The current study aimed to determine the most common microorganisms involved in diabetic foot infection in order to minimize the failure of antibiotic therapy and the risk of developing complications.Patients and Methods:All patients with diabetic foot infection admitted to the infectious diseases, surgery and endocrinology wards of two teaching hospitals from 2007 to 2010 (n = 196) were recruited. In this retrospective study, demographic characteristics, type of lesions, history of hospitalization/antibiotic therapy, isolated microorganisms, clinical complications, administered treatment (medical or surgical) and outcome were recorded.Results:Patients’ mean age was 60.84 (± 10.30) years. Totally, 113 (57.65%) of the patients were male and 83 (42.35%) were female. According to Wagner’s grading, deep ulcers with/without osteomyelitis accounted for the majority of lesions. A single microorganism was isolated (most common: Escherichia coli, Staphylococcus aureus and Klebsiella spp.) from 81 of the patients (80.20%); while for the remaining polymicrobial infection was reported. Isolated pathogens showed no significant correlation with duration of diabetes, type of the lesions (P = 0.13) and history of hospitalization (P = 0.61). The majority of patients (n = 118, 60.20%) were treated surgically; however 11 patients expired due to sepsis. Amputation (most common at toes and below the knee) was performed for 89 patients (45.40%). The response rate to medical treatment was 31.6% for single-pathogen and 10% for polymicrobial infection (with a 30% mortality rate).Conclusions:Physicians are recommended to take microbiological cultures before starting empirical therapy recommended to cover Gram-negative microorganisms in order to lower the risk of antibiotic resistance.

show abstract

“…The aim of DFU prevention should be to teach self-foot care to patients and to examine their foot at each reconsultation. Studies have reported that training increases the knowledge about diabetic foot and the tendency to care for their feet in high-risk patients, thus, decreasing the frequency of DFU and amputation (7,8).…”

Section: Introductionmentioning

confidence: 99%

Knowledge and Practice of Foot Care in Diabetic Inpatients: A Descriptive Cross-Sectional Study

Dündar¹,

Akıncı²

2017

Erciyes Med J

View full text Add to dashboard Cite

Objective: To determine whether diabetic patients have adequate information regarding foot care. Materials and Methods:We evaluated history of diabetic foot ulcer (DFU) and data on self-foot care practices collected through face-to-face interviews from 64 diabetic inpatients in a university hospital. Foot care practices were scored based on 20 questions. Questions under the categories of "beware of risky behavior," "foot and nail care," and "elaborate on footwear" were grouped, and the practice subscores and total scores were calculated. A total score of >70% was assessed as "good practice", 50%-70% as "satisfactory practice," and <50% as "poor practice."Results: Fourteen (21.9%) patients had previous or ongoing DFU and five (7.8%) had undergone amputation. Only 44% of the patients stated that they had been informed about the prevention of diabetic foot after the diagnosis was established. This group differed from the uninformed group significantly in terms of regular medical control (p=0.006). The average foot care practice score was 72 for the informed group and 49 for the uninformed group; the percentage of "good practice" score was 46% in the informed group and 11% in the uninformed group. The percentages of having good practice score were found to be significantly high in women, those without DFU, and those informed about foot care (p<0.01).Conclusion: Foot care practices of the patients were found to be mainly inadequate. Health care providers and diabetic patients should be encouraged for good foot care practices.

show abstract

Incidence, risk factors for amputation among patients with diabetic foot ulcer in a Chinese tertiary hospital

Cited by 68 publications

References 31 publications

HDL cholesterol as a predictor for the incidence of lower extremity amputation and wound-related death in patients with diabetic foot ulcers

HDL cholesterol as a predictor for the incidence of lower extremity amputation and wound-related death in patients with diabetic foot ulcers

Diabetic Foot: Infections and Outcomes in Iranian Admitted Patients

Knowledge and Practice of Foot Care in Diabetic Inpatients: A Descriptive Cross-Sectional Study

Contact Info

Product

Resources

About