Incidencia de asma y factores de riesgo en una cohorte de escolares desde los 6-7 años hasta los 14-15 años en Castellón, según el Estudio Internacional de Asma y Alergias en la Infancia (ISAAC)

Arnedo, Alberto; Bellido, Juan B.; Pac, María Rosario; Artero, A. Urbón; Campos, Joan-Baptista; Museros, Lidón; Puig-Barberà, Joan; Tosca, Ricardo; Tornador, Ester

doi:10.1157/13107792

Cited by 14 publications

(1 citation statement)

References 29 publications

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“…The relationship between COVID-19, caused by SARS-CoV-2 virus, and asthma has not been determined in the pediatric population. According to the International Study of Asthma and Allergies in Childhood (ISAAC) 1 , the average prevalence in children in Spain is 10.3%, a rate similar to that of the European Union.…”

Section: Introductionmentioning

confidence: 99%

Is Asthma a Risk Factor for Covid-19 in Children?

Calvo

Hernaiz

Escolano

et al. 2021

Preprint

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The prevalence of asthma in children in Europe is an average of 10.3%. The role of asthma as a risk factor for COVID-19 in children is unknown. Our aim was to study the prevalence of asthma in children with SARS-CoV-2 infection and to compare them in hospitalized children and those with mild ambulatory symptoms. We conducted an observational retrospective study in 99 children (between 3- 17 years of age) with a confirmed SARS-CoV-2 infection between March and December 2020. The existence of a history of asthma was investigated using the validated ISAAC questionnaire and clinical data on COVID-19 were compiled. The median age was 10 years (IQR=13-5), and 60/99 (60.6%) patients had mild infections controlled as outpatient, while 39/99 (39.4%) required admission. The prevalence of asthma ─affirmative response to question 6 of the ISAAC questionnaire─ was 11.1% (11/99). The prevalence of asthma in children who required admission increased to 17.9% and to 21.4% in patients requiring PICU, while in outpatients children was 6.7% (p=0.079). We found a significant association between the use of salbutamol during the last year and the need for admission (23.1% in hospitalized patients vs 3.3% in outpatients; OR= 8.7, 95%CI 1.7-42.8). Likewise, budesonide treatment in the last year (17.9% vs 1.7%, OR= 12.9, 95%CI 1.5-109.5) was also a risk factor for admission. Therefore, a history of asthma was not a risk factor for SARS-CoV-2 infection in our series, but active asthma could be a risk factor for severity and need for hospitalization for COVID-19 in children

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Section: Introductionmentioning

confidence: 99%