Incidencia y factores predictivos de anemia ferropénica tras una hemorragia digestiva alta no asociada a hipertensión portal

Rubinat, Montserrat Planella de; Amorós, Montserrat Teixidó; Clau, Raquel Ballester; Cabello, J. Trujillano; Escuer, Mercedes Ibarz; Espinet, Josep Maria Reñé

doi:10.1016/j.gastrohep.2015.02.012

Cited by 10 publications

(10 citation statements)

References 24 publications

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“…The last group was patients with moderate or severe anemia at admission (≤10 g/dl). Low Hb (≤10 g/dl) at baseline is, as one would expect, predictive of subsequent anemia 18. Hb less than 10 g/dl has been shown to be an independent predictor for rebleeding, need for intervention, or death following AGIB 42.…”

Section: Discussionmentioning

confidence: 91%

“…The first group included older patients (≥75 years). Older age is a known risk factor for anemia, often associated with iron deficiency or renal insufficiency 37, and has been reported to increase the risk of anemia after AGIB 18. Older patients may also be more likely to experience rebleeding and in-hospital mortality than younger patients 6,38,39.…”

Section: Discussionmentioning

confidence: 99%

“…Changes in Hb to both timepoints were also analyzed in the following subgroups: (i) patients aged younger than 75 or older than or equal to 75 years at admission (ii) patients with a Charlson comorbidity index less than 3 or at least 3 and (iii) patients with Hb above 10 g/dl or up to 10 g/dl at admission to hospital. These subgroups were considered to be high-risk populations: older age is associated with a higher risk of mortality; comorbidity as measured by the Charlson comorbidity index incurs a higher risk of mortality; and the Hb level indicates the severity of the GI bleeding (Hb≤10 g/dl at hospital admission predicts iron deficiency anemia at 30 days after AGIB 18).…”

Section: Methodsmentioning

confidence: 99%

“…Longer-term restoration of normal Hb levels after AGIB, however, is often neglected. Current recommendations do not address the use of iron supplementation 13,14 despite the fact that anemia affects 50–80% of patients discharged after AGIB 16–18 and iron deficiency has been documented in ~50% of patients at discharge 19. Management of anemia is clearly important in this population, but a survey conducted in Canada in 2016 found that fewer than 15% of clinicians prescribe iron therapy in patients who are anemic after AGIB, and that oral iron is the selected mode of administration in 80% of treated patients 20.…”

Section: Introductionmentioning

confidence: 99%

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Clinical experience with ferric carboxymaltose in the management of anemia in acute gastrointestinal bleeding

Ballester-Clau

Vicente

Voltà-Pardo

et al. 2019

European Journal of Gastroenterology &Amp; Hepatology

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ObjectiveThe aim of this study was to assess the efficacy and safety of intravenous ferric carboxymaltose (FCM) following hospitalization for acute gastrointestinal bleeding (AGIB) in the context of a restrictive transfusion strategy.Patients and methodsA retrospective single-center study analyzed patients with AGIB (excluding AGIB secondary to portal hypertension) administered a single FCM dose with or without blood transfusion.ResultsEighty-six episodes in 84 patients were analyzed. Seventy-nine patients had upper AGIB. Nineteen episodes were associated with hemodynamic instability. FCM was administered during hospitalization as a single dose of 1000 mg iron in 84/86 episodes and as a single dose of 500 mg iron in two episodes, with blood transfusion in 60/86 (69.8%) episodes. The mean hemoglobin (Hb) was 9.0 g/dl at admission, 7.6 g/dl at the lowest in-hospital value, 9.4 g/dl at discharge, and 12.7 g/dl at follow-up (mean: 55 days postdischarge) (P<0.001 for follow-up vs. all other timepoints). The lowest mean in-hospital Hb value was 7.2 and 8.8 g/dl, respectively, in patients with transfusion+FCM versus FCM alone; the mean Hb was 12.4 versus 13.7 g/dl at follow-up. In patients administered FCM alone, the mean Hb at follow-up in the subpopulations aged older than or equal to 75 years (n=33), Charlson comorbidity index of at least 3 (n=48), and Hb of up to 10 g/dl at admission (n=47) were 12.6, 13.1, and 13.3 g/dl, respectively. No adverse effects were detected.ConclusionTreatment with FCM for AGIB is associated with a good erythropoietic response and anemia correction after hospitalization, even in severe episodes or when transfusion is needed. FCM is safe and well tolerated, and may support a restrictive transfusion policy.

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Clinical experience with ferric carboxymaltose in the management of anemia in acute gastrointestinal bleeding

Ballester-Clau

Vicente

Voltà-Pardo

et al. 2019

European Journal of Gastroenterology &Amp; Hepatology

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“…Blood loss typically occurs from either the gastrointestinal tract or heavy bleeding during menstruation (16,73). An estimated 61% of individuals with gastrointestinal bleeding have anemia (73), with a number of additional cases potentially undiagnosed (24).…”

Section: Microcytic Anemiamentioning

confidence: 99%

Anemia: Considerations for the Athletic Population

Russ¹

2022

Strength &Amp; Conditioning Journal

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Anemia is a condition characterized by too few red blood cells, leading to diminished oxygen delivery, which can significantly impact exercise participation and athletic performance. The etiology of anemia is multifactorial. Some forms of anemia develop as a result of deficiencies in specific vitamins and minerals and may be modifiable, whereas other types are inherited disorders. Although nonmodifiable, the latter may be managed with the assistance of trained medical professionals. This article will provide an overview of the pathophysiology associated with common forms of anemia and provide an introduction to diagnostic testing procedures and treatment options. Additionally, the signs and symptoms will be discussed to help strength and conditioning professionals recognize this potentially impactful condition. This article concludes with a discussion of the influence iron deficiency has on sports participation.

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Open questions and misconceptions in the diagnosis and management of anemia in patients with gastrointestinal bleeding

Mearin

Lanas

Bujanda

et al. 2018

Gastroenterología y Hepatología (English Edition)

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Incidencia y factores predictivos de anemia ferropénica tras una hemorragia digestiva alta no asociada a hipertensión portal

Cited by 10 publications

References 24 publications

Clinical experience with ferric carboxymaltose in the management of anemia in acute gastrointestinal bleeding

Clinical experience with ferric carboxymaltose in the management of anemia in acute gastrointestinal bleeding

Anemia: Considerations for the Athletic Population

Open questions and misconceptions in the diagnosis and management of anemia in patients with gastrointestinal bleeding

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