Incidental demyelination in magnetic resonance imaging and 10‐year risk of multiple sclerosis: A data lake cohort study

Abstract

With increasing use of magnetic resonance imaging (MRI), clinicians have observed a steady increase in incidental findings. A recent meta-analysis uncovered an incidental finding of any nature in 1 of 37 brain MRIs (2.7%) in neurologically asymptomatic individuals [1].In 2009, Okuda defined "radiologically isolated syndrome" (RIS) [2] as a situation where a radiological finding suggestive of demyelinating