Incidental Detection of Factor XII Deficiency Following Coronary Artery Bypass Grafting

The Standard Point-of-Care Hemochron Jr. ACT+ Test in Monitoring Heparin Administration for Cardiopulmonary Bypass in Severe Factor XII Deficiency

“…cardiac surgery (2)(3)(4)(5)(6)(7)(8). Although graft thrombosis following coronary artery bypass graft surgery in fXII deficiency has been described (3), it remains unclear whether the risk of thromboembolism is generally elevated.…”

“…When 300 Austrian blood donors were screened for fXII activity, one severe deficiency was detected, suggesting a maximal prevalence of 0.3% in the normal European population (1). However, an incidence of 1 in one million individuals has been estimated (8).…”