Incidental Detection of Multiple Abdominopelvic Splenosis Sites During Tc-99m HMPAO-Labeled Leukocyte Scintigraphy

Abstract

Splenosis is heterotopic autotransplantation and seeding of splenic tissue, and it can be found anywhere in the abdominal cavity. We present a case of multiple abdominopelvic splenosis in a postsplenectomy patient detected incidentally during Tc-99m HMPAO-labeled leukocyte scintigraphy 30 years after the traumatic event. REFERENCES1. Bidet AC, Dreyfus-Schmidt G, Mas J, et al. Diagnosis of splenosis: the advantages of splenic scintiscanning with Tc-99m heat-damaged red blood cells. Eur J Nucl Med. 1986;12:357-358. 2. Laflamme L, Boucher L. Splenosis detected by heat-denaturated Tc-99m red blood cell scintigraphy. Clin Nucl Med. 2003;28:39 -42. 3. Castellani M, Cappellini MD, Cappelletti M, et al. Tc-99m sulphur colloid scintigraphy in the assessment of residual splenic tissue after splenectomy. Clin Radiol. 2001;56:596 -598. 4. Greschus S, Hackstein N, Puille MF, et al. Extensive abdominal splenosis: imaging features. Abdom Imaging. 2003;28:866 -867. 5. Martin F, Lomena F, Fuster D, et al. Hepatosplenic scintigraphy in a case of multiple abdominal splenosis. Rev Esp Med Nucl. 2000;19:452. 6. Glazer M, Sagar VV. Accessory splenic tissue detection with Tc-99m labeled WBC in a post-splenectomy patient. Clin Nucl Med. 1995;20: 283. 7. Spencer RP, Pannullo AM, Karimeddini MK. 'Ineffective' splenosis detected on Tc-99m labeled white cell imaging.

Abdominal Multiple Splenosis Mimicking Liver and Colon Tumors: A Case Report and Review of the Literature

“…To be more specific, radioisotopic scintigraphy with (99m)Tc labelled heat-denatured erythrocytes is the technique with the greatest specificity in the demonstration of splenic tissue. In contrast, Turkmen et al13. suggest that splenosis could be detected by Tc-99m HMPAO-labeled leukocyte scintigraphy.…”

Intrahepatic splenosis mimicking hepatoma

“…Splenosis may form when viable splenic cells and pulp spill and implant 2. Although splenosis can occur anywhere, the implants are found most commonly in the peritoneal cavity, such as mesentery, omentum and other peritoneal surfaces 3. If splenic rupture is associated with a diaphragmatic tear, the implants may seed the pleural cavity or pericardium, which causes intrathoracic splenosis 4.…”