Incidental detection of pigmented lesions in the cervix

Handa, Uma; Mohan, Harsh; Garg, Shailja

doi:10.1111/j.1479-828x.2007.00730.x

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2016

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(2 citation statements)

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“…Concerning immunohistochemical features, the tumor cells were described as being positive for S100 protein, HMB45 and MART-1 [2,3,4,5,6,7,13]. Surprisingly, however, the immunohistochemical features described in latest edi- tion of a gynecopathology textbook were different from our findings and previous reports; that is, this textbook stated that endocervical blue nevi are usually negative for HMB45 and MART-1 [10].…”

Section: Discussioncontrasting

confidence: 56%

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Blue nevus presenting as an endocervical polyp

Masuko¹,

Kato²,

Iwai³

2016

pjp

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We report herein a case of blue nevus of the uterine cervix presenting as an endocervical polyp. A 58-year-old Japanese female was presented with an endocervical polyp. The polyp was promptly excised, and histological examination revealed distribution of many melanin-loaded spindle-shaped cells in its stromal portion. Immunohistochemically, the cells were positive for S100 protein, SOX10, HMB45, and MART-1. Based on the characteristic cellular morphology and immunohistochemical findings, the lesion was diagnosed as a blue nevus, and malignant melanoma was denied. Endocervical blue nevi are relatively rare, and there are some discordance among previous publications about immunoreactivity against HMB45 and MART-1.

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Section: Discussioncontrasting

confidence: 56%

“…Blue nevi of the uterine cervix are benign melanocytic neoplasms, which were once considered to be rare and were usually found incidentally in hysterectomy specimens [1,2,3,4,5,6,7,8].…”

Section: Introductionmentioning

confidence: 99%