Incidental Extramammary Findings on Preoperative Breast MRI in Breast Cancer Patients: A Pictorial Essay

Ryoo, Jin-A; Kim, Shin Young

doi:10.3348/jksr.2022.0076

Cited by 3 publications

(2 citation statements)

References 21 publications

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“…Obviously, all of this data needs to be clarified because it has to be specified that food from the Mediterranean Sea has been linked to an augmented risk of cancer due to some chemical components. For example, it could contain different pollutants and compounds, including estrogens which can cause an increased risk of DNA abnormalities and mitotic activity, leading, in turn, to an uncontrolled proliferation typical of cancer [62][63][64][65][66][67][68][69][70][71][72][73][74][75][76][77][78]. Specific molecules such as breast cancer susceptibility gene 1 (BRCA1) and miRNAs permit the characterization of the genetic profile of the disease and a correct screening of patients [79].…”

Section: Breast Cancermentioning

confidence: 99%

Gender Differences and miRNAs Expression in Cancer: Implications on Prognosis and Susceptibility

Caserta

Gangemi

Murdaca

et al. 2023

IJMS

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MicroRNAs are small, noncoding molecules of about twenty-two nucleotides with crucial roles in both healthy and pathological cells. Their expression depends not only on genetic factors, but also on epigenetic mechanisms like genomic imprinting and inactivation of X chromosome in females that influence in a sex-dependent manner onset, progression, and response to therapy of different diseases like cancer. There is evidence of a correlation between miRNAs, sex, and cancer both in solid tumors and in hematological malignancies; as an example, in lymphomas, with a prevalence rate higher in men than women, miR-142 is “silenced” because of its hypermethylation by DNA methyltransferase-1 and it is blocked in its normal activity of regulating the migration of the cell. This condition corresponds in clinical practice with a more aggressive tumor. In addition, cancer treatment can have advantages from the evaluation of miRNAs expression; in fact, therapy with estrogens in hepatocellular carcinoma determines an upregulation of the oncosuppressors miR-26a, miR-92, and miR-122 and, consequently, apoptosis. The aim of this review is to present an exhaustive collection of scientific data about the possible role of sex differences on the expression of miRNAs and the mechanisms through which miRNAs influence cancerogenesis, autophagy, and apoptosis of cells from diverse types of tumors.

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Section: Breast Cancermentioning

confidence: 99%

Gender Differences and miRNAs Expression in Cancer: Implications on Prognosis and Susceptibility

Caserta

Gangemi

Murdaca

et al. 2023

IJMS

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“…During the timeframe in which they have the expander in place, patients could need to undergo breast MRI for reasons unrelated to the evaluation of potential expander-related complications, e.g., for the assessment of metachronous symptomatic or non-symptomatic breast lesions detected during the follow-up in the ipsi- or contra-lateral breast [ 46 ]. Notably, the clinical management of these patients could also require an MRI examination of other organs to investigate secondary cancer, potentially also identified as collateral findings on the breast MRI performed after the insertion of the expander [ 47 ]. In these cases, the patients may be required to undergo abdominal MRI [ 48 ], brain MRI [ 49 ], and spinal MRI [ 50 ].…”

Section: Discussionmentioning

confidence: 99%

MRI-Conditional Breast Tissue Expander: First In-Human Multi-Case Assessment of MRI-Related Complications and Image Quality

Schiaffino,

Cozzi,

Pompei

et al. 2023

JCM

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This study aims to assess potential complications and effects on the magnetic resonance imaging (MRI) image quality of a new MRI-conditional breast tissue expander (Motiva Flora®) in its first in-human multi-case application. Twenty-four patients with 36 expanders underwent non-contrast breast MRI with T1-weighted, T2-weighted, and diffusion-weighted imaging (DWI) sequences on a 3 T unit before breast tissue expander exchange surgery, being monitored during and after MRI for potential complications. Three board-certified breast radiologists blindly and independently reviewed image quality using a four-level scale (“poor”, “sufficient”, “good”, and “excellent”), with inter-reader reliability being assessed with Kendall’s τb. The maximum diameters of RFID-related artifacts on T1-weighted and DWI sequences were compared with the Wilcoxon signed-rank test. All 24 examinations were completed without patient-related or device-related complications. The T1-weighted and T2-weighted sequences of all the examinations had “excellent” image quality and a median 11 mm (IQR 9–12 mm) RFID artifact maximum diameter, significantly lower (p < 0.001) than on the DWI images (median 32.5 mm, IQR 28.5–34.5 mm). DWI quality was rated at least “good” in 63% of the examinations, with strong inter-reader reliability (Kendall’s τb 0.837, 95% CI 0.687–0.952). This first in-human study confirms the MRI-conditional profile of this new expander, which does not affect the image quality of T1-weighted and T2-weighted sequences and moderately affects DWI quality.

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Incidental findings in preoperative computed tomography images of robotic-assisted total joint replacement: a multi-center retrospective study

Lei,

Zhang,

Luo

et al. 2024

BMC Surg

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Background The majority of robot-assisted total joint arthroplasties necessitate preoperative computed tomography (CT) scans. Incidental findings in these CT scans can introduce complexity into clinical treatment decisions. Consequently, this study sought to document the nature and frequency of incidental findings identified in preoperative CT imaging conducted for robot-assisted total joint arthroplasty, along with their impact on planned surgical procedures.Methods This investigation constitutes a retrospective review encompassing patients who underwent primary robot-assisted total hip arthroplasty between January 2020 and January 2022 at the Second Affiliated Hospital of Xi'an Jiaotong University, the First Affiliated Hospital of Peking University, and Nanfang Hospital. It also includes patients who underwent robot-assisted total knee arthroplasty during the same period at the Second Affiliated Hospital of Xi'an Jiaotong University, the

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Incidental Extramammary Findings on Preoperative Breast MRI in Breast Cancer Patients: A Pictorial Essay

Cited by 3 publications

References 21 publications

Gender Differences and miRNAs Expression in Cancer: Implications on Prognosis and Susceptibility

Gender Differences and miRNAs Expression in Cancer: Implications on Prognosis and Susceptibility

MRI-Conditional Breast Tissue Expander: First In-Human Multi-Case Assessment of MRI-Related Complications and Image Quality

Incidental findings in preoperative computed tomography images of robotic-assisted total joint replacement: a multi-center retrospective study

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