Incidental Finding of a Chemodectoma in a Dog: Differential Diagnosis

Balaguer, L.; Romano, Jacinta; Nieto, Jose-Maria; Vidal, Sergio; Alvarez, Carmen Rodríguez

doi:10.1177/104063879000200417

Cited by 10 publications

(13 citation statements)

References 7 publications

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“…The morphologic, anatomic and histologic findings of these cases are consistent with that of canine aortic body tumor, and of previous descriptions (BALAGUER et al, 1990;CAPEN, 2002;BROWN et al, 2003;CAPEN, 2007). Additionally, the positive NSE immunoreactivity was similar to other reports of chemodectomas in dogs (BALAGUER et al, 1990;BROWN et al, 2003).…”

Section: Palavras-chave: Cão Coração Tumor Do Corpo Aórtico Imunoisupporting

confidence: 74%

Aortic body tumors in dogs from Northern Paraná, Brazil

et al. 2009

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Section: Palavras-chave: Cão Coração Tumor Do Corpo Aórtico Imunoisupporting

confidence: 74%

Aortic body tumors in dogs from Northern Paraná, Brazil

et al. 2009

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“…Based on morphological and immunohistochemical findings, the diagnosis was malignant aortic body tumor and PHS, which is similar to previous descriptions of these tumors in dogs [1][2][3][4][5]7]. The expression of chromogranin A and synaptophysin in the heart base tumor was low; this might indicate malignancy, since it has been reported that concentration of secretory granules of chromogranin is diminished in malignant tumors [2].…”

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confidence: 61%

Simultaneous Aortic Body Tumor and Pulmonary Histiocytic Sarcoma in a Flat-Coated Retriever

Nakagawa

Sakai

Yanai

et al. 2009

The Journal of Veterinary Medical Science

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ABSTRACT. A case of multiple primary tumors observed in the heart base and in the lung of a 7-year-old intact female, flat-coated retriever was reported. Morphological differences between both tumors and detailed immunohistochemical study revealed that the cardiac neoplasm was as a malignant aortic body tumor and the lung tumor was a pulmonary histiocytic sarcoma. The occurrence of aortic body tumor with other primary neoplasms has been previously reported in animals suggesting that this might be a common presentation in dogs.KEY WORDS: aortic body tumor, canine, multiple tumor, pulmonary histiocytic sarcoma.J. Vet. Med. Sci. 71(9): 1221-1223, 2009 Multiple primary tumors (MPTs) were defined as multiple autonomously originating tumors in an individual patient by Warren and Gates [18]. The occurrence of more than 1 primary cancer in an animal, previously only a medical curiosity, has now become a worldwide problem; however, there are few studies on this interesting entity in veterinary literature [8,9,16]. The present paper describes the histopathological and immunohistochemical findings of a malignant aortic body chemodectoma and pulmonary histiocytic sarcoma (PHS) in a flat-coated retriever.A 7-year-old intact female, flat-coated retriever was admitted to the Veterinary Hospital, Gifu University, Japan, with severe dyspnea. Thoracic X-ray images revealed severe pleural effusion and a large heart-base tumor. At needle thoracocentesis an opaque, red-whitish (chylous effusion) fuid was observed. A sample of the pleural effusion was collected for cytology, which demonstrated mesothelial cells, macrophages, and lymphocytes, suggestive of modified transudate. Neoplastic cells were not observed. Despite symptomatic treatment, in early July, she showed severe subcutaneous edema and dyspnea and died during hospitalization.Necropsy revealed 2 hard, encapsulated, reddish, coalescent masses (8  7  6 cm and 3  3  2 cm) arising at the heart base, around the ascending aorta (Fig. 1a). Moreover, a large (7  5 cm) whitish mass with an irregular surface was observed in the right caudal pulmonary lobe (Fig. 2a). The thoracic cavity contained approximately 2.5 l of an opaque, red-whitish fluid (chylous effusion) with a moderate amount of fibrin, hydropericardium, concentric hypertrophy of the left ventricule, and ascites. On the other organs, abnormality was not seen.In microscopic observation, the cardiac neoplasm was comprised of multiple lobules separated by fine connective tissue septa. The tumor cells were cuboidal to polyhedral with lightly basophilic granular cytoplasm and prominent round nuclei (Fig. 1b). Mitotic figures were frequent, and some blood vessels showed neoplastic invasion. In the lung, round to polyhedral tumor cells arranged in a solid pattern were observed to replace the pulmonary parenchyma, while there were areas preserving normal alveolar and bronchiolar architecture. These cells had ample eosinophilic cytoplasm and round to oval nuclei (Fig. 2b). Binucleated and multinucleated giant cells, a small n...

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“…La evaluación post-mortem reveló mucosas De todas las especies de animales domésticos, son en los caninos los que con mayor frecuencia se diagnostica este tipo de tumor, le siguen los gatos y después los bovinos (11). Las razas Bulldog, así como los Bóxer y los Boston Terrier, son considerados como los más susceptibles a padecer con frecuencia este tipo de tumor (3,8,11,12,13).…”

Section: Resultados Y Discusiónunclassified

“…Casos de quimiodectomas en caninos fueron descritos en varios estudios siendo la infiltración auricular izquierda por células neoplásicas reportada sólo en uno de ellos (3,7,8,9,10,11,12).…”

Section: Resultados Y Discusiónunclassified

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Hallazgo Incidental De Un Quimiodectoma en Un Canino Bulldog Inglés

Díaz¹,

Moreno

Suárez

et al. 2015

Compend. cienc. vet

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ABSTRACT. The present study describes macroscopic and microscopic findings in a canine English Bulldog , female, 6 years with sudden death and suspicious of poisoning. The animal was referred for post-mortem evaluation to the Pathology Sciences Department of Veterinary FacultyNational University of Asunción (UNA) . The necropsy revealed an unique irregular protuberance (4 x 2.5 cm) located at the heart base external to the aorta, invading adventicia and infiltrating left atrium myocardium with focal central necrosis. Histopathological examination showed polygonal, round and oval cells with granular cytoplasm, histologic characteristics of neoplastic chemoreceptor cells. Keywords RESUMEN.En el presente estudio se describen hallazgos macroscópicos y microscópicos de un quimiodectoma en un canino, Bulldog inglés, hembra, de 6 años con muerte súbita y diagnóstico presuntivo de envenenamiento. El cadáver del animal se remitió al Departamento de Ciencias Patológicas de la Facultad de Ciencias Veterinarias (FCV) -Universidad Nacional de Asunción (UNA) para el estudio post-mortem. La necropsia reveló una protuberancia única, irregular (4 x 2,5cm) localizada en la base del corazón, periférica a la aorta, invadiendo adventicia e infiltrando miocardio auricular izquierdo con necrosis focal central. Al examen histopatológico de la protuberancia se constató una población celular compuesta por células poligonales, redondeadas y ovales con citoplasma granular, características histológicas de células quimiorreceptoras neoplásicas.Palabras clave: quimiodectoma, cuerpo aórtico, canino, corazón.

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Incidental Finding of a Chemodectoma in a Dog: Differential Diagnosis

Cited by 10 publications

References 7 publications

Aortic body tumors in dogs from Northern Paraná, Brazil

Aortic body tumors in dogs from Northern Paraná, Brazil

Simultaneous Aortic Body Tumor and Pulmonary Histiocytic Sarcoma in a Flat-Coated Retriever

Hallazgo Incidental De Un Quimiodectoma en Un Canino Bulldog Inglés

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