Incidental Finding of a Left Atrial Myxoma while Characterising an Autoimmune Disease

García-Carretero, Rafael; Naranjo-Mansilla, Gema; Luna-Heredia, Esther; Arias-Baldo, Paloma; Vela, Blanca N. Beamonte

doi:10.2478/jccm-2018-0009

Cited by 5 publications

(4 citation statements)

References 13 publications

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“…Constitutional symptoms: Cardiac myxomas are commonly associated with constitutional symptoms mimicking inflammatory or connective tissue disorders[ 75 - 77 ]. These symptoms are more common in women than in men, in right-sided myxomas than in left-sided ones and in large and multicentric myxomas[ 78 ].…”

Section: Introductionmentioning

confidence: 99%

Cardiac myxomas: A narrative review

Islam¹

2022

WJC

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Cardiac myxomas are common primary neoplasms of the heart. They are biologically benign but “functionally malignant” because of the potential for embolization. They arise most commonly from the left atrium, but no chambers of the heart are immune. They may be sporadic in the majority but also familial as a part of the Carney complex. Two morphological forms exist: polypoid and papillary. Polypoid myxomas often present with obstructive features, while the papillary forms are more prone to embolization. Histogenesis is still controversial; the current view centres around origin from the primitive pluripotent mesenchymal cells. They may be of giant proportion, be calcified or get infected. Clinical presentation typically involves the triad of intracardiac obstruction, embolic events and constitutional symptoms. Precordial examination findings may simulate those of mitral or tricuspid stenosis. The presence of tumour plop and change of the physical findings with changing position may help differentiation between the two. Echocardiography is the investigation of choice. Echogenic polypoid or papillary mobile mass within the atrial cavity remaining attached to the interatrial septum through a stalk are the tell-tale echocardiographic features. Cardiac magnetic resonance and computed tomographic scanning may have incremental diagnostic value. Histopathological examination reveals abundant loose myxoid stroma with scattered round, polygonal or stellate cells with dense irregular nuclei. Genetic testing may detect mutations in the PRKAR1A gene in the familial form of cardiac myxoma, i.e. the Carney complex. Surgical excision is the mainstay of treatment with low operative mortality, excellent postoperative survival and low recurrence rate. The current trend favours minimal-access surgery with or without robotic assistance. Physicians should have appropriate preparedness to make a timely diagnosis and enthusiastic treatment to avoid potentially fatal complications.

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Section: Introductionmentioning

confidence: 99%

Cardiac myxomas: A narrative review

Islam¹

2022

WJC

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“…Angio-TAC: stop circulatorio por oclusión arterial al final de la aorta e inicio de ambas femorales (Figura 1); a nivel craneal diferencia de calibre carotideo con datos de obstrucción: isquemia periférica la presencia de ANA 6 , ANCA 7 , anticuerpos antifosfolipídicos 8 , trombocitopenia 9 , entre otros. La citocina más descrita corresponde a la IL-6 5,6,7,10 .…”

Section: Casounclassified

Mixoma cardiaco como causa de isquemia en niños. Reporte de casos

Quintero,

Kegler,

Filizzola

et al. 2023

Rev. parag. reumatol.

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El mixoma cardiaco constituye uno de los tumores benignos más frecuentes entre los tumores cardiacos. El mismo se caracteriza por la obstrucción del flujo sanguíneo por trombosis o émbolo, resultando en causa de insuficiencia cardiaca con disfunción ventricular, síncope ortostático, isquemia de diferentes órganos de acuerdo a la arteria afectada, e incluso muerte súbita. Presentamos 2 casos en pacientes pediátricos: el primer caso, una adolescente con ACV isquémico y el segundo caso se trata de un adolescente con isquemia a nivel de miembros inferiores por una tromboembolia en la Aorta distal. En ambos casos se realizó la exéresis del tumor, con éxito.

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“…Although extremely rare, myxomas are the most common cardiac tumors, accounting for more than 50% of all cases worldwide. 1 , 2 Despite being histologically benign, myxomas can have a wide spectrum of presentations based on their anatomic location, size, and mobility. They can mimic various heart conditions and present as cardiac insufficiency, valvular heart disease, syncope, peripheral embolic events, and systemic symptoms.…”

Section: Introductionmentioning

confidence: 99%

Large Left Atrial Myxoma Discovered During Restaging of Breast Cancer

Feghali,

Rhythm Vasudeva,

Edwin Feghali

et al. 2024

kjm

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Incidental Finding of a Left Atrial Myxoma while Characterising an Autoimmune Disease

Cited by 5 publications

References 13 publications

Cardiac myxomas: A narrative review

Cardiac myxomas: A narrative review

Mixoma cardiaco como causa de isquemia en niños. Reporte de casos

Large Left Atrial Myxoma Discovered During Restaging of Breast Cancer

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