Incidental PET/CT Findings of Suspected COVID-19 in a Region of High Prevalence

Franceschi, Ana M.; Clifton, Michael; Ahmed, Osama; Matthews, Robert; Franceschi, Dinko

doi:10.7759/cureus.9716

Cited by 4 publications

(4 citation statements)

References 20 publications

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“…All of the patients with findings suggestive of COVID-19 infection were confirmed positive upon further workup. Mo et al [ 66 ] reported similar findings in another asymptomatic 60-year oncology patient in the United States with human papillomavirus, and Franceschi et al [ 67 ] reported a similar scenario in an asymptomatic 61-year-old patient with treated primary diffuse large B-cell lymphoma. Wakfie-Corieh et al [ 68 ] retrospectively reviewed 1079 oncologic 18 F-FDG PET-CT scans performed between February 2 and May 18, 2020 to identify lung and extraparenchymal lung involvement in asymptomatic cancer patients with COVID-19.…”

Section: Asymptomatic Covid-19 Oncology Patientsmentioning

confidence: 75%

“…Infection with COVID-19 may remain asymptomatic and appears as incidental findings in nuclear imaging procedures performed for standard oncologic indications[ 63 - 67 ]. PET-CT findings are considered sensitive for the detection of early COVID-19 infection, even before its detection as nasal viral carriage[ 41 , 55 , 66 ].…”

Section: Asymptomatic Covid-19 Oncology Patientsmentioning

confidence: 99%

“…Some theories explain the FDG activity detected in COVID-19 pulmonary lesions is the result of viral replication after the viral particles penetrate the cells. This replication starts to overwhelm the cellular structure, inciting a proinflammatory state that disrupts the infected and adjacent endothelium, leading to increased FDG uptake[ 67 ].…”

Section: Asymptomatic Covid-19 Oncology Patientsmentioning

confidence: 99%

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Incidental radiological findings suggestive of COVID-19 in asymptomatic patients

Romeih¹,

Mahrous²,

Kassas³

2022

WJR

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Despite routine screening of patients for coronavirus disease 2019 (COVID-19) symptoms and signs at hospital entrances, patients may slip between the cracks and be incidentally discovered to have lung findings that could indicate COVID-19 infection on imaging obtained for other reasons. Multiple case reports and case series have been published to identify the pattern of this highly infectious disease. This article addresses the radiographic findings in different imaging modalities that may be incidentally seen in asymptomatic patients who carry COVID-19. In general, findings of COVID-19 infection may appear in computed tomography (CT), magnetic resonance imaging, positron emission tomography-CT, ultrasound, or plain X-rays that show lung or only apical or basal cuts. The identification of these characteristics by radiologists and clinicians is crucial because this would help in the early recognition of cases so that a rapid treatment protocol can be established, the immediate isolation to reduce community transmission, and the organization of close monitoring. Thus, it is important to both the patient and the physician that these findings are highlighted and reported.

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Section: Asymptomatic Covid-19 Oncology Patientsmentioning

confidence: 75%

Section: Asymptomatic Covid-19 Oncology Patientsmentioning

confidence: 99%

Section: Asymptomatic Covid-19 Oncology Patientsmentioning

confidence: 99%

See 1 more Smart Citation

Incidental radiological findings suggestive of COVID-19 in asymptomatic patients

Romeih¹,

Mahrous²,

Kassas³

2022

WJR

View full text Add to dashboard Cite

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“…Currently ongoing COVID-19 pandemic, has led to an increase in the number of CT scans performed due to a presumed diagnosis of pneumonia worldwide (8). This has caused various diseases and/or medical conditions to be noticed incidentally in CT examinations (15,16,17). On the other hand, this situation could be seen as an opportunity to retrospectively examine the relationships between various parameters through these CT scans with more objective measurements.…”

Section: Discussionmentioning

confidence: 99%

May hepatic steatosis be associated with gynecomastia and epicardial fat? A retrospective study of 599 male patients

Aksoy¹,

Aydın²,

Yurdaışık³

et al. 2021

Preprint

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Objective There is no study in the literature investigating the association of hepatic steatosis with both gynecomastia and epicardial fat thickness together. We aimed to determine the correlations between hepatic steatosis through liver density, gynecomastia and epicardial fat thickness in patients undergoing CT scans due to suspected COVID-19 symptoms. Methods A total of 599 male patients who underwent chest CT scans due to a presumed diagnosis of COVID-19 in our radiology clinic were included in the study. Patients’ age, diameters of the subareolar glandular tissues of the right and left breasts, the right retroareolar fatty tissue, liver and spleen density, epicardial fat thickness and biochemical parameters were recorded and analyzed. The laboratory analyses were performed according to the standard methods. Results The mean age of the patients was 47.21±15.00 years. The left subareolar tissue thickness and the right retroareolar fatty tissue thickness that are used to indicate the presence of gynecomastia were found to be significantly correlated with liver density in negative direction (r=-.137, p<0.001; r=-.172, p<0.001; respectively). Epicardial fat thickness was statistically significantly correlated with right subareolar tissue thickness (r=.085, p=0.037), left subareolar tissue thickness (r=.101, p=0.014) and right retroareolar fatty tissue thickness (r=.148, p<0.001). Conclusion The results of this study showed that gynecomastia was significantly correlated with both age and hepatic steatosis. Epicardial fat thickness was also associated with liver steatosis. We demonstrated the significant correlations between epicardial fat thickness and gynecomastia for the first time. Nevertheless, our results need to be confirmed by further comprehensive studies.

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