Incidentally detected lesions on contrast‐enhanced MR imaging in candidates for breast‐conserving therapy: Correlation between MR findings and histological diagnosis

Yabuuchi, Hidetake; Kuroiwa, Toshiro; Kusumoto, Chie; Fukuya, Tatsuro; Ohno, Shinji; Hachitanda, Yoichi

doi:10.1002/jmri.20532

Cited by 19 publications

(11 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a study of 48 incidentally detected breast lesions in 299 patients prepared for breast-conserving therapy, 25 lesions were proved to be benign and 23 proved to be malignant. Lesions of over 10 mm tended to be malignant and lesions equal or less than 5 mm tended to be benign [21]. A large-scale study in evaluation of 969 breast cancer patients showed that MRI detected 3.1% (30/969) of clinically and mammographically occult breast cancer in the contralateral breast.…”

Section: Discussionmentioning

confidence: 99%

Magnetic resonance imaging features of fibrocystic change of the breast

Chen

Liu

Baek

et al. 2008

Magnetic Resonance Imaging

View full text Add to dashboard Cite

Purpose-Studies specifically reporting MR imaging of fibrocystic change (FCC) of the breast are very few and its MR imaging features are not clearly known. The purpose of this study was to analyze the MR imaging features of FCC of the breast.Materials and Methods-Thirty one patients of pathologically proved FCC of the breast were retrospectively reviewed. The MRI study was performed using a 1.5 T MR scanner with standard bilateral breast coil. The imaging protocol consisted of pre-contrast T1W imaging and dynamic contrast-enhanced axial T1W imaging. The MRI features were interpreted based on the morphologic and enhancement kinetic descriptors defined on ACR BIRADS-MRI lexicon.Results-FCC of the breast had a wide spectrum of morphologic and kinetic features on MRI. Two types of FCC were found, including a more diffuse type of non-mass lesion (12/31, 39%) showing benign enhancement kinetic pattern with medium wash-in in early phase (9/10, 90%) and a focal mass type lesion (11/31, 35%) with enhancement kinetic usually showing rapid up-slope mimicking a breast cancer (8/11, 73%).Conclusion-MRI is able to elaborate the diverse imaging features of fibrocystic change of the breast. Our result showed that FCC presenting as focal mass type lesion were usually over-diagnosed as malignancy. Understanding MR imaging of FCC is important to determine which cohort of patients should be followed up alone or receive aggressive management.

show abstract

Section: Discussionmentioning

confidence: 99%

Magnetic resonance imaging features of fibrocystic change of the breast

Chen

Liu

Baek

et al. 2008

Magnetic Resonance Imaging

View full text Add to dashboard Cite

show abstract

“…Dynamic contrast-enhanced breast MR imaging (DCE-MRI) has been reported to have high sensitivity for cancer detection, reportedly as high as 88%-100%, but specificity may be relatively low as 68%-96% (4 -6,8,9). The high diagnostic value of the time-intensity curve (TIC) derived from DCE-MRI has been well documented in past studies (1)(2)(3)(4)(5)(6)(7)(8)(9)(10). Moreover, MR imaging has recently been used to analyze combined morphologic characteristics and kinetic enhancement patterns of breast lesions, and a combination of these parameters shows high positive predictive value (8,9).…”

mentioning

confidence: 98%

“…MAGNETIC RESONANCE IMAGING (MRI) of the breast is increasingly used as an important tool for detecting breast cancer or preoperative diagnosis of breast cancer to determine the area of tumor spreading or to find additional lesions (1)(2)(3)(4)(5)(6)(7). Dynamic contrast-enhanced breast MR imaging (DCE-MRI) has been reported to have high sensitivity for cancer detection, reportedly as high as 88%-100%, but specificity may be relatively low as 68%-96% (4 -6,8,9).…”

mentioning

confidence: 99%

Enhanced mass on contrast‐enhanced breast MR imaging: Lesion characterization using combination of dynamic contrast‐enhanced and diffusion‐weighted MR images

Yabuuchi

Matsuo

Okafuji

et al. 2008

Magnetic Resonance Imaging

Self Cite

176

166

View full text Add to dashboard Cite

Purpose:To evaluate the diagnostic accuracy of a combination of dynamic contrast-enhanced MR imaging (DCE-MRI) and diffusion-weighted MR imaging (DWI) in characterization of enhanced mass on breast MR imaging and to find the strongest discriminators between carcinoma and benignancy. Materials and Methods:We analyzed consecutive breast MR images in 270 patients; however, 13 lesions in 93 patients were excluded based on our criteria. We analyzed tumor size, shape, margin, internal mass enhancement, kinetic curve pattern, and apparent diffusion coefficient (ADC) values. We applied univariate and multivariate analyses to find the strongest indicators of malignancy and calculate a predictive probability for malignancy. We added the corresponding categories to these prediction probabilities for malignancy and calculated diagnostic accuracy when we consider category 4b, 4c, and 5 lesions as malignant and category 4a, 3, and 2 lesions as benign. In a validation study, 75 enhancing lesions in 71 patients were examined consecutively.Results: Irregular margin, heterogeneous internal enhancement, rim enhancement, plateau time-intensity curve (TIC) pattern, and washout TIC pattern were the strongest indicators of malignancy as well as past studies, and ADC values less than 1.1 ϫ 10 Ϫ3 mm 2 /s were also the strongest indicators of malignancy. In a validation study, sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were 92% (56/61), 86% (12/14), 97% (56/58), 71% (12/17), and 91% (68/75), respectively. Conclusion:The combination of DWI and DCE-MRI could produce high diagnostic accuracy in the characterization of enhanced mass on breast MR imaging.

show abstract

“…Nodular enhancements in general tend to have smooth edges and size no larger than 2cm. Yabuuchi H et al [25] found that lesions larger than 10 mm tended to be malignant, and lesions equal or smaller than 5 mm tended to be benign. Lesions with early enhancement peak tended to be malignant, whereas those with persistent enhancement tended to be benign [25].…”

Section: Mri Featuresmentioning

confidence: 99%

“…Yabuuchi H et al [25] found that lesions larger than 10 mm tended to be malignant, and lesions equal or smaller than 5 mm tended to be benign. Lesions with early enhancement peak tended to be malignant, whereas those with persistent enhancement tended to be benign [25]. Also, Liberman L et al [26] studied the importance of lesion size on the positive predictive value (PPV) of biopsy in MRI detected breast lesions.…”

Section: Mri Featuresmentioning

confidence: 99%

Something as Simple and as Complex as Fibrocystic Masthopathy Review of MRI Findings in a Case Report

Fernadez¹

2017

IJRRT

View full text Add to dashboard Cite

Purpose: conduct a review of the findings on MRI of fibrocystic breast disease, taking into account existing short bibliography about it, from a complex case registered in our service.Discussion: A large part of both clinical and subclinical lesions found in our daily work are benign and correspond with fibrocystic changes (FCC). This entity is complex and part exhibit traits that define characteristically in MRI and diagnose correctly, but there is another small group of changes that can take the image aspect of cancer. From a complex case, we review the main aspects of the FCC in MRI face to better understand a very common condition, although, but at the same time unknown in MRI technique.Conclusion: more than 50% of lesions we see in the context of FCC show morphological and kinetic criteria of malignancy, so in the present moment we cannot avoid biopsies. The most relevant features in MRI in the FCC is non-mass regional enhancement and predominantly curves type II. Keywords: Breast; MRI; Mastopathy; Fibrocystic change; FCC; Predominantly; Lump ReviewThis is the case of 39 years old woman, with no family history of breast cancer, with painless palpable lump recently appeared on CSI left breast, without blushing or heat. The patient comes to our Unit to start imaging studies. Mammographic, ultrasonographic and MR breast findings, and anatomo-pathological analysis are described below. In the mammography we can see a left global asymmetry that primarily affects upper quadrants (Figure 1), associating faint and few fine and heterogeneous scattered microcalcifications. Sonographically a mass measuring 47mm, consisting of numerous small and simple cysts grouped, with some ectatic canalicular segments and moderate hyperemia regional (Figure 2) with a hard and stiff behavior in the US-elastography, so additional histological study is made.

show abstract

Incidentally detected lesions on contrast‐enhanced MR imaging in candidates for breast‐conserving therapy: Correlation between MR findings and histological diagnosis

Cited by 19 publications

References 21 publications

Magnetic resonance imaging features of fibrocystic change of the breast

Magnetic resonance imaging features of fibrocystic change of the breast

Enhanced mass on contrast‐enhanced breast MR imaging: Lesion characterization using combination of dynamic contrast‐enhanced and diffusion‐weighted MR images

Something as Simple and as Complex as Fibrocystic Masthopathy Review of MRI Findings in a Case Report

Contact Info

Product

Resources

About