Incisional Recurrence of a Cervical Carcinoma

Greenlee, Robert M.

doi:10.1001/jama.1981.03320010049032

Cited by 32 publications

(11 citation statements)

References 2 publications

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“…Most of the patients had occult cervical cancer during pregnancy, so could not be correctly diagnosed until delivery. Except three cases of Stage III, and one case of Stage II, all of the other cases were Stage I cervical cancers (1,(6)(7)(8)(9)(10)(11)(12) . The histologic type was SCC in ten patients including our case and cervical adenocarcinoma in four other patients.…”

Section: Discussionmentioning

confidence: 99%

Advanced stage of cervical carcinoma undiagnosed during antenatal period in term pregnancy and concomitant metastasis on episiotomy scar during delivery: a case report and review of the literature

Baloğlu¹,

Uysal²,

Aslan³

et al. 2007

Int J Gynecol Cancer

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The objective of this study is to review the implantation of malignant cells of cervical cancer in an episiotomy site. This is the second case of cervical cancer with concomitant episiotomy metastasis in the literature. The treatment consisted of radiochemotherapy. There was no confirmed recurrent disease after 1 year of follow-up in our reported case. In conclusion, pregnancy appears to be a chance for cervical cancer screening as a part of prenatal care. If cervical cancer is diagnosed in a woman after vaginal delivery, she must be examined carefully including the episiotomy site.

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Section: Discussionmentioning

confidence: 99%

Advanced stage of cervical carcinoma undiagnosed during antenatal period in term pregnancy and concomitant metastasis on episiotomy scar during delivery: a case report and review of the literature

Baloğlu¹,

Uysal²,

Aslan³

et al. 2007

Int J Gynecol Cancer

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“…Fewer reports have explored the prognostic implications for recurrence in an episiotomy scar in women with cervical cancer during pregnancy (5) . Implantation of tumor cells has been reported in abdominal incisions (21,22) and has led some to postulate the role of a dampened immune system during pregnancy on permitting these recurrences (12) . It may be important to make a distinction between tumor metastases and tumor implants since the latter may have a different biology and prognostic implications for locoregional and distant spread (21,22) .…”

Section: Discussionmentioning

confidence: 99%

“…Implantation of tumor cells has been reported in abdominal incisions (21,22) and has led some to postulate the role of a dampened immune system during pregnancy on permitting these recurrences (12) . It may be important to make a distinction between tumor metastases and tumor implants since the latter may have a different biology and prognostic implications for locoregional and distant spread (21,22) . It is hypothesized that the mechanism of these recurrences is related to mechanical rather than lymphatic spread as there is no evidence to date to support the notion that pregnancy accelerates tumor growth or spread.…”

Section: Discussionmentioning

confidence: 99%

Villoglandular adenocarcinoma of the cervix recurrent in an episiotomy scar: a case report in a 32-year-old female

Heron¹,

Axtel²,

Gerszten³

et al. 2005

Int J Gynecol Cancer

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Cervical cancer during pregnancy is rare, occurring in approximately 3% of cervical cancer cases. Considerable controversy exists as to the long-term prognosis of patients diagnosed during pregnancy. A 32-year-old female presented with vaginal spotting in April 1998. A prenatal smear in December 1996 revealed atypical glandular cells of undetermined significance. A sterile speculum exam in April 1997 at 31-week gestational age revealed a polyp on the anterior lip of the cervix, pathology consistent with a well-differentiated villoglandular adenocarcinoma. In August 1997, the patient underwent a radical hysterectomy with pelvic/para-aortic lymphadenectomy. In April 2001, she represented with nodular perineal mass in the episiotomy incision. She received preoperative radiotherapy with a near-complete response and remained without disease for >10 months. It appears that a less radical procedure can offer significant therapeutic value. Preoperative radiotherapy proved effective at achieving a near-complete response. The patient underwent a wide local excision of the perineal area with resultant negative margins.

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“…The third probable contributor to the development of metastases at sites of altered skin, tumor stroma, is demonstrated by Jones and Rous in their study. They show that connective tissue which is reacting to a mechanical insult grows profusely and rapidly when incubated in plasma 15–16 . One can speculate that a very active connective (granulation) tissue which can more readily proliferate and support the growth of tumor cells may enhance the establishment of metastasis in injured tissue.…”

Section: Discussionmentioning

confidence: 99%

Occult Adenocarcinoma Metastatic to a Skin Graft Donor Site

Grenier

Kaplan

1985

The Journal of Dermatologic Surgery and Oncology

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Internal malignancies present with metastases to the skin 0.4% of the time. Cutaneous metastases not uncommonly develop in areas of damaged skin such as radiodermatitis and surgical scars. This report involves a 78-year-old male with metastatic adenocarcinoma from an unknown primary site that presented in a split-thickness skin graft donor site. This appears to be the first reported case of internal malignancy metastatic to skin altered by grafting.

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Incisional Recurrence of a Cervical Carcinoma

Cited by 32 publications

References 2 publications

Advanced stage of cervical carcinoma undiagnosed during antenatal period in term pregnancy and concomitant metastasis on episiotomy scar during delivery: a case report and review of the literature

Advanced stage of cervical carcinoma undiagnosed during antenatal period in term pregnancy and concomitant metastasis on episiotomy scar during delivery: a case report and review of the literature

Villoglandular adenocarcinoma of the cervix recurrent in an episiotomy scar: a case report in a 32-year-old female

Occult Adenocarcinoma Metastatic to a Skin Graft Donor Site

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