Abstract. Most research studies on Life Satisfaction/Subjective Wellbeing (SWB) have focused on one main determinant and a variety of social demographic variables to delineate the determinants of life satisfaction. However, very few research studies examine life satisfaction from a holistic approach. The aim of this study was to utilize a holistic approach to construct a causal model and identify major determinants of life satisfaction. This study utilized data from the General Social Survey, with a sample size of 19,597. Several multiple regression models were run sequentially to estimate standardized path coefficients for the causal model. Overall, above average satisfaction with life was reported by Canadian respondents. Respondents who were female, younger, married, from high socioeconomic status background, born in Canada, very religious, and demonstrated high level of neighborhood interaction had greater satisfaction with life. Similarly, respondents had greater life satisfaction if they had better health, social contact, leisure activities, more time with family and friends, more enjoyment with volunteer activities, and a greater sense of belonging to the community. Our results suggest that a holistic approach is necessary for understanding the causal process of life satisfaction. A significant number of causal connections contradict some of the findings in literature today. We have provided some possible explanations for these anomalies and policy implications.