Incompatibilité fœto-maternelle érythrocytaire ABO : sévérité clinique !

Brouk, Hacene; Refai, S.; Zemouli, A.; Djabri, Yacine; Boukartouta, N.; Ouelaa, Hanifa

doi:10.1016/j.tracli.2013.03.070

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“…Gordon [15] in Kenya and Brouk [16] in Algeria also used first-line phototherapy. Intensive phototherapy, the effectiveness of which is proven in severe hyperbilirubinemias, not available in Brazzaville, was the most used therapeutic method by Brouk [16].…”

Section: Discussionmentioning

confidence: 99%

Jaundice in the Newborn at the Teaching Hospital of Brazzaville

Bowassa¹,

Ngono²,

Ngakengni³

et al. 2019

OJPed

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Introduction: Jaundice is a major symptom during neonatal time. It is defined by a bilirubin ≥ 50 mg/l. Objectives: To determine the frequency of neonatal jaundice at the Brazzaville University Hospital, to determine the main etiologies, to evaluate the management, to specify the evolution. Patients and Method: It was a prospective and descriptive study that was conducted in the . It included newborn children admitted into the neonatal unit for treatment of jaundice. The variables studied were epidemiological, clinical, etiological therapy and outcome. Results: The frequency of the neonatal jaundice is 7.2%. The hyperbilirubinemia as not conjugated was found in 99.1% of cases. The main causes are bacterial neonatal infection n = 102 (47.9%), the physiological icterus n = 46 (21.6%) and the ABO incompatibility n = 40 (18.8%). The treatment consists of the phototherapy in all cases. Each phototherapy session lasts 3 hours n = 99 (56.9%), 6 hours n = 58 (33.3%) and 12 hours n = 17 (9.8%). The average duration of the administering of the therapy is of 3 ± 2 days. Hyperbilirubinemia encephalopathy occurred in 62 (29.1%) cases, including 49 cases of kernicterus. The death occurred in 70 (32.9%) children. Conclusion: The importance and the gravity of the neonatal jaundice require primary preventive means based on proper care in pregnancy and the birth. While the secondary prevention includes high index of suspicion, comprehensive diagnostic equipment availability to prevent acute bilirubin encephalopathy.

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Section: Discussionmentioning

confidence: 99%