Background and Aims: Sacrum is formed by the fusion of five sacral vertebrae and forms the lower part of Vertebral column. Anatomical variations, Morphology and Morphometry of Sacral hiatus are important clinically as well as surgically. Materials and Methods: This study was carried out on 75 dry human sacra of unknown sex to know Anatomical variations of sacrum. Results: Anatomical variations-failure of formation of superior articular process and lamina of left first sacral vertebra, incomplete development and fusion of second sacral vertebra, multiple foraminas on either side of spinous process above the sacral hiatus, multiple foraminas in the dorsal surface of base of the sacrum behind the auricular surface, incomplete median crest, Sacralisation of fifth lumbar vertebrae were identified. Conclusions: The knowledge of anatomical variations of Sacrum and variations of sacral hiatus are clinically important for caudal epidural block in Pediatric, Obstetric, Orthopedic, Urologic and Surgical practice.