Incorporation of Selenium-75 into Dog Hair

McConnell, Kenneth P.; Kreamer, A. E.

doi:10.3181/00379727-105-26048

Cited by 12 publications

(1 citation statement)

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“…As might be expected from published work (McConnell and Kreamer 1960;Rosenfield 1962), the activity of the wool increased between the seventh and 28th days. The specific activity of the wool actually produced during this period was undoubtedly very much greater than that measured, since the sample area was not shorn before the experiment and the sample contained the inactive wool already present.…”

Section: Discussionsupporting

confidence: 83%

The distribution and excretion of radioselenium in sheep

Wright¹

1965

New Zealand Journal of Agricultural Research

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Radioactive selenium was injected into five sheep which were killed at intervals from two hours to 28 days afterwards. When plotted against time the ratios of the specific activities of tissues to that of blood gave parallel curves rising rapidly at first and then more slowly. After 28 days these ratios were: liver 2.8, pancreas 2.5, ovary 2.0, abomasum 1.5, cardiac muscle 1.3, skin 0.8, with lower values for other tissues with the exception of kidney and adrenal. The ratios for kidney rose rapidly to 12.9 after 24 hours and then slowly fell to 11.2 after 28 days. The rates of excretion in urine and faeces reached early maxima and then declined until about 20 days, when they increased once more. During the 28 days 12 per cent of the dose was excreted in the urine and 10 per cent in the faeces.

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Section: Discussionsupporting

confidence: 83%

The distribution and excretion of radioselenium in sheep

Wright¹

1965

New Zealand Journal of Agricultural Research

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Dietary selenium in humans toenails as an indicator

Morris

Stampfer

Willett

1983

Biol Trace Elem Res

110

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Mounting laboratory and epidemiologic evidence suggests that selenium may be important in the etiology of both cancer and heart disease. We explored the use of hair and nails as indicators of selenium intake by measuring their selenium levels using neutron activation analysis, a highly sensitive and precise nondestructive technique. Levels in duplicate samples of nails, hair, and blood were all reasonably reproducible. However, selenium-containing shampoos severely contaminated some of the hair specimens, suggesting that use of hair in epidemiologic studies could be misleading. The mean selenium level in toenails from South Dakota (a known high selenium area) was 1.17 ppm (1SE = 0.09). This was significantly higher than mean levels from Boston and Georgia (medium selenium intake area) of 0.74 ppm (0.04) and 0.81 (0.03), respectively. The mean selenium level in toenails from New Zealand (low selenium area) was 0.26 (0.02) and these levels did not overlap those of other areas. The South Dakota specimens showed marked familial aggregation, probably reflecting dietary differences. Since toenails vary in length, clippings from different toes represent different time periods of formation; clippings from all ten toes reflect selenium levels integrated over an extended period. As toenails are easily collected, transported, and stored, and reflect longterm intake, they can be useful in epidemiologic studies of selenium and chronic disease.

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Pharmacology and toxicology of heavy metals: Arsenic

Klevay

1976

Pharmacology & Therapeutics. Part A: Chemotherapy, Toxicolo

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Incorporation of Selenium-75 into Dog Hair

Cited by 12 publications

References 1 publication

The distribution and excretion of radioselenium in sheep

The distribution and excretion of radioselenium in sheep

Dietary selenium in humans toenails as an indicator

Pharmacology and toxicology of heavy metals: Arsenic

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