Increase in coronary blood flow by intra-aortic balloon counterpulsation in a porcine model of myocardial reperfusion

Bonios, Michael; Pierrakos, Charalampos; Argiriou, Michael; Dalianis, Argirios; Terrovitis, John; Dolou, Paraskevi; Drakos, Stavros G.; Koudoumas, Dimitrios; Charitos, Christos; Anastasiou-Nana, Maria

doi:10.1016/j.ijcard.2008.08.015

Cited by 24 publications

(24 citation statements)

References 39 publications

(34 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Coronary hyperemia was observed after I/R, although numbers did not reach statistical significance. Reactive hyperemia of the infarct-related vessel is a well-known phenomenon in swine [24]. In an experimental animal setting it has previously been shown that IABP and Impella® improved blood flow in a noninfarct-related coronary artery [16].…”

Section: Discussionmentioning

confidence: 99%

Support with intra-aortic balloon pump vs. Impella2.5® and blood flow to the heart, brain and kidneys — An experimental porcine model of ischaemic heart failure

Helgestad

Poulsen

Christiansen

et al. 2015

International Journal of Cardiology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Support with intra-aortic balloon pump vs. Impella2.5® and blood flow to the heart, brain and kidneys — An experimental porcine model of ischaemic heart failure

Helgestad

Poulsen

Christiansen

et al. 2015

International Journal of Cardiology

View full text Add to dashboard Cite

“…Furthermore, the finding that, after PCI, the experimental group had a higher percentage of patients with TIMI class III compared with the control group may be correlated with a lower incidence of microembolization in the experimental group, after PCI. 18 This is presumably because IABP counterpulsation increased the recanalization rate of infarcted vessels, preoperatively. Studies have shown that IABP treatment decreases the incidence of 'no reflow' and 'slow flow' after PCI.…”

Section: -17mentioning

confidence: 99%

“…'No reflow' or 'slow flow' are very common post-PCI phenomena in patients with large areas of AMI, in whom their incidence is between 0.6% and 2%. 18 However, the mechanism underlying the occurrence of 'no reflow' or 'slow flow' remains controversial. 18 It is assumed that the obstruction of distal blood capillaries is caused by coronary artery microthrombi, with plaque debris being the major mechanism of 'no reflow'.…”

Section: -17mentioning

confidence: 99%

“…18 However, the mechanism underlying the occurrence of 'no reflow' or 'slow flow' remains controversial. 18 It is assumed that the obstruction of distal blood capillaries is caused by coronary artery microthrombi, with plaque debris being the major mechanism of 'no reflow'. Morishima et al 19 found that a decrease in LVEF, in addition to left ventricular dilatation and reconstruction, led to an increase in MACE events.…”

Section: -17mentioning

confidence: 99%

See 1 more Smart Citation

Early application of an intra-aortic balloon pump in patients with ST-segment elevation acute myocardial infarction scheduled for elective percutaneous coronary intervention

Dong

Liu

et al. 2013

J Int Med Res

View full text Add to dashboard Cite

Objective: This study evaluated the effect of early application of intra-aortic balloon pump (IABP) counterpulsation in patients with ST-segment elevation acute myocardial infarction (STEMI), scheduled for elective percutaneous coronary intervention (PCI). Methods: Patients who had experienced STEMI for 12-72 h received (IABP group) or did not receive (control group) IABP counterpulsation for 3-5 days before PCI. Results: One hundred patients were included. Frequencies of infarct-related artery thrombolysis in acute myocardial infarction (TIMI) flow rate classes 0, I and II in the IABP group (11.5, 1.9 and 7.7%, respectively) were significantly lower than in the control group (29.1, 14.6 and 22.9%, respectively) before PCI. After PCI, the frequency of TIMI class III flow rate in the IABP group (96.2%) was significantly higher than that in the control group (81.3%). Four weeks after PCI, the left ventricular ejection fraction (LVEF) was significantly higher, and the incidence of major cardiac events was significantly lower, in the IABP group compared with the control group. Conclusions: Early use of IABP counterpulsation in STEMI patients scheduled for PCI was effective, with a favourable safety profile. IABP counterpulsation reduced the incidence of major adverse cardiac events and improved LVEF. However, IABP devices must be used at an early stage, to obtain optimal results.

show abstract

“…IABP, the most commonly used device for mechanical circulatory support, has been proven to improve LCOS and left-ventricular failure following CABG via reducing the left-ventricular afterload and myocardial oxygen consumption, improving the subendocardial perfusion and promoting the redistribution of coronary blood flow to the ischemic myocardium [8,14,15,16,17]. In addition, IABP helps to improve the hemodynamic stability and reduce the myocardial oxygen consumption when the heart is displaced to expose and then graft the target coronary artery during OPCABG, especially in high-risk patients [11].…”

Section: Discussionmentioning

confidence: 99%

Prophylactic Application of an Intra-Aortic Balloon Pump in High-Risk Patients Undergoing Off-Pump Coronary Artery Bypass Grafting

Ding

Wei

et al. 2015

Cardiology

View full text Add to dashboard Cite

Background: An intra-aortic balloon pump (IABP) is the most commonly used circulatory assist device in cardiac surgery. We hypothesized that prophylactic application of an IABP improves early clinical outcome of high-risk patients undergoing scheduled off-pump coronary artery bypass grafting (OPCABG). Methods: From January 2010 to December 2013, hemodynamically stable, high-risk patients undergoing scheduled OPCABG with preincision use of an IABP were recruited to the IABP group. Using the propensity score-matching method, every patient in the IABP group was matched with another patient (the control group) with a similar propensity score who received an IABP on an as-needed basis during or after OPCABG. Surgical mortality and major morbidity rates were compared between groups. Results: A total of 116 patient pairs were included in this study. In patients in the IABP group, postoperative low cardiac output and respiratory as well as renal failure were less frequent, intensive care unit stay was shorter, and surgical mortality was lower compared to patients in the control group. In multivariate logistic regression, timing of IABP implantation, as an independent risk factor, was associated with postoperative low cardiac output (OR = 2.02, 95% CI 1.28-5.76), respiratory failure (OR = 1.86, 95% CI 1.19-4.27), renal failure (OR = 2.96, 95% CI 1.51-6.63) and surgical mortality (OR = 2.45, 95% CI 1.42-6.07). Conclusions: Prophylactic application of an IABP improves postoperative cardiac performance, reduces respiratory and renal complications, and consequently lowers surgical mortality in high-risk patients undergoing scheduled OPCABG.

show abstract

Increase in coronary blood flow by intra-aortic balloon counterpulsation in a porcine model of myocardial reperfusion

Cited by 24 publications

References 39 publications

Support with intra-aortic balloon pump vs. Impella2.5® and blood flow to the heart, brain and kidneys — An experimental porcine model of ischaemic heart failure

Support with intra-aortic balloon pump vs. Impella2.5® and blood flow to the heart, brain and kidneys — An experimental porcine model of ischaemic heart failure

Early application of an intra-aortic balloon pump in patients with ST-segment elevation acute myocardial infarction scheduled for elective percutaneous coronary intervention

Prophylactic Application of an Intra-Aortic Balloon Pump in High-Risk Patients Undergoing Off-Pump Coronary Artery Bypass Grafting

Contact Info

Product

Resources

About