-The epidemiology of deliberate selfpoisoning presentations to the emergency department (ED) of Ninewells Hospital was reviewed over a six-month period. The results were related to previously published Scottish data. During the six month period, 530 patients presented (2.1% of total). There was a female preponderance with over 65% of patients aged less than 40 years. Patients lived more commonly in areas of higher deprivation. The drugs most commonly involved were paracetamol (39.25%) and antidepressants (35.1%). Of the presentatons 80.2% required no treatment apart from basic observations. Only 1.51% received activated charcoal and no gastric lavages were performed. Of the presentations, 75.6% were discharged after observation in the ED, 8.9% were admitted to a psychiatric hospital and 5.5% were admitted to general medicine department. Deliberate self-poisoning continues to be a major cause of hospital admissions in Scotland. In Tayside, it is predominantly a problem of the young and socially deprived. Consistent with recent national trends, paracetamol was the most common drug relating to overdose. The use of an ED observation ward is supported as a vast majority of patients are admitted for less than 24 hours and require no active treatment.