Increase in the incidence of parotid gland tumors in the years 2005–2014

Stryjewska-Makuch, Grażyna; Kolebacz, Bogdan; Janik, Małgorzata; Wolnik, Agnieszka

doi:10.5604/01.3001.0009.8412

Cited by 26 publications

(28 citation statements)

References 14 publications

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“…These results also revealed an increased incidence trend unlike other countries like Spain . This observation corresponds to the results reported in several other studies, including studies that reported a significant increase from 1975 to 1988 and 2005 to 2014, and other SEER‐based studies that reported an increase in incidence from 1973 to 2009 . Notwithstanding, we have found an improvement in the incidence trend of major SGC.…”

Section: Discussionsupporting

confidence: 92%

Examined and positive lymph nodes counts and lymph nodes ratio are associated with survival in major salivary gland cancer

et al. 2019

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Background We aimed to investigate the prognostic role of examined (dissected) lymph nodes (ELNs), negative LNs (NLNs), and positive (metastatic) LNs (PLNs) counts and LN ratio (LNR = PLNs/ELNs×100) in patients with major salivary gland cancer (SGC). Methods Data were retrieved for major SGC patients diagnosed between 1988 and 2011 from Surveillance, Epidemiology, and End Results program. Results We have included 5446 patients with major SGC. Most patients had parotid gland cancer (84.61%). Patients having >18 ELNs, >4 PLNs, and >33.33% LNR were associated with a worse survival. Moreover, older age, male patients, grade IV, distant stage, unmarried patients, submandibular gland cancer, and received chemotherapy but not received surgery were significantly associated with a worse survival. Conclusions We demonstrated that patients with >18 ELNs and >4 PLNs counts, and >33.33% LNR were high‐risk group patients. We strongly suggest adding the ELNs and PLNs counts and/or LNR into the current staging system.

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Section: Discussionsupporting

confidence: 92%

Examined and positive lymph nodes counts and lymph nodes ratio are associated with survival in major salivary gland cancer

et al. 2019

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“…The tumors are commonly located in parotid glands followed by the submandibular glands, the minor salivary glands, and the sublingual glands. Overall, from 62% to 87% of salivary gland neoplasms are benign . The 2 most common benign neoplasms are pleomorphic adenoma and Warthin tumor, whereas the most common malignant tumor is mucoepidermoid carcinoma…”

Section: Introductionmentioning

confidence: 99%

Risk of malignancy associated with cytomorphology subtypes in the salivary gland neoplasm of uncertain malignant potential (SUMP) category in the Milan System: A bi‐institutional study

Chowsilpa

Lose

et al. 2019

Cancer Cytopathology

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BACKGROUND: Salivary gland neoplasm of uncertain malignant potential (SUMP) is a diagnostic category in the Milan System for Reporting Salivary Gland Cytopathology. The objective of this study was to assess the risk of neoplasm (RON) and the risk of malignancy (ROM) in SUMP cases by evaluating them based on their prominent cytomorphology. METHODS:The pathology databases were searched for cases of fine-needle aspiration-diagnosed SUMP at The Johns Hopkins Hospital and Northwestern University from 2013 to 2018. Only cytopathology cases diagnosed as SUMP that had available surgical follow-up were included. RESULTS: Sixty-five patients with SUMP were identified, including 31 men and 34 women who ranged in age from 15 to 87 years (mean age, 55.2 years). Sixty-five cases had histologic follow-up, including 13 (20%) with basaloid features, 13 (20%) with oncocytic features, and 39 (60%) with unspecified features. No cases with clear cell features were found. Overall, the RON in the SUMP category was 95.4% (62 of 65 cases), and the ROM was 33.8% (22 of 65 cases). The RON in SUMPs with basaloid, oncocytic, and unspecified subtypes was 92.3%, 100%, and 94.9%, respectively, whereas the ROM was 38.5%, 7.7%, and 41%, respectively. The most common benign neoplasm was pleomorphic adenoma (23.1%), whereas mucoepidermoid carcinoma (9.2%) was the most common malignant neoplasm. CONCLUSIONS: This study shows that the ROM differs significantly based on cytomorphology subtypes, whereas the overall ROM is approximately the same as the target rate in the Milan System for Reporting Salivary Gland Cytopathology. Moreover, the RON remains high in the SUMP category among different cytomorphology subtypes.Adequate sampling, immunohistochemical staining, and familiarity with metaplastic and reactive changes may improve the diagnosis.

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“…Salivary gland cancers are rare, constituting 3-11% of all head and neck neoplasms and 0.2% of all malignancies, depending on the author [1][2][3]. Most occur in the sixth decade of life [4].…”

Section: Introductionmentioning

confidence: 99%

Salivary gland cancer — epidemiology

Kordzińska-Cisek¹,

Grzybowska‐Szatkowska²

2018

Nowotwory. Journal of Oncology

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Salivary gland tumors represent 3-11% of all head and neck cancers and 0.2% of all neoplasms. Among Poles, malignancies involving the large salivary glands constituted 0.3% of all malignancies in Poland and 9.7% of head and neck neoplasms. In 2014, the morbidity rate was higher among women, but over the past 15 years there has been a slight prevalence among men. As for benign neoplasms in Poland, the most commonly seen are pleomorphic adenoma and Warthin's tumor. Cystic glandular cancer, mucoid epidermal carcinoma and adenocarcinoma are among the most frequent malignancies. Less common are lymphoma and squamous cell carcinoma. Salivary gland neoplasms are usually located in the parotid gland, then in the sub-mandibular gland. The best prognosis is for women whose cancers are located in the parotid gland and those with lobular carcinoma. Figures have been on the rise lately, however. Deaths have been on a stable level.

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Increase in the incidence of parotid gland tumors in the years 2005–2014

Abstract: A significant increase in the incidence of benign tumours, especially mixed and Warthin tumours, was demonstrated. There was no significant increase in the number of malignant tumours over the analysed period of time.

Cited by 26 publications

References 14 publications

Examined and positive lymph nodes counts and lymph nodes ratio are associated with survival in major salivary gland cancer

Examined and positive lymph nodes counts and lymph nodes ratio are associated with survival in major salivary gland cancer

Risk of malignancy associated with cytomorphology subtypes in the salivary gland neoplasm of uncertain malignant potential (SUMP) category in the Milan System: A bi‐institutional study

Salivary gland cancer — epidemiology

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