Increase in the Strength of Synchronization between the Baroreflex Waves of Blood Pressure and Heart Rate Due to the Lower Body Negative Pressure Effect

Negulyaev, V. O.; Orlova, Ekaterina; Sharova, Anna; Тарасова, О.С.; Виноградова, О. Л.; Боровик, А. С.

doi:10.1134/s0362119721040125

Cited by 3 publications

(2 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is consistent with previous findings regarding the use of EECP by athletes to suppress the vagal activity of the autonomic nervous system during recovery from exercise fatigue ( Valenzuela et al, 2018 ). Similarly, negative lower body pressure interventions increased the intensity of heartbeat–blood pressure coupling in the spontaneous state ( Negulyaev et al, 2021 ).…”

Section: Discussionmentioning

confidence: 99%

A study on the immediate effects of enhanced external counterpulsation on physiological coupling

Liu

Hui

et al. 2023

Front. Neurosci.

View full text Add to dashboard Cite

IntroductionEnhanced external counterpulsation (EECP) is a non-invasive assisted circulation technique for its clinical application in the rehabilitation and management of ischemic cardiovascular and cerebrovascular diseases, which has complex physiological and hemodynamic effects. However, the effects of EECP on the coupling of physiological systems are still unclear. We aimed to investigate the immediate effects of EECP on the coupling between integrated physiological systems such as cardiorespiratory and cardiovascular systems.MethodsBased on a random sham-controlled design, simultaneous electrocardiography, photoplethysmography, bio-electrical impedance, and continuous hemodynamic data were recorded before, during and after two consecutive 30 min EECP in 41 healthy adults. Physiological coupling strength quantified by phase synchronization indexes (PSI), hemodynamic measurements and heart rate variability indices of 22 subjects (female/male: 10/12; age: 22.6 ± 2.1 years) receiving active EECP were calculated and compared with those of 19 sham control subjects (female/male: 7/12; age: 23.6 ± 2.5 years).ResultsImmediately after the two consecutive EECP interventions, the physiological coupling between respiratory and cardiovascular systems PSIRES–PTT (0.34 ± 0.14 vs. 0.49 ± 0.17, P = 0.002), the physiological coupling between cardiac and cardiovascular systems PSIIBI–PTT (0.41 ± 0.14 vs. 0.52 ± 0.16, P = 0.006) and the total physiological coupling PSItotal (1.21 ± 0.35 vs. 1.57 ± 0.49, P = 0.005) in the EECP group were significantly lower than those before the EECP intervention, while the physiological coupling indexes in the control group did not change significantly (P > 0.05).ConclusionOur study provides evidence that the PSI is altered by immediate EECP intervention. We speculate that the reduced PSI induced by EECP may be a marker of disturbed physiological coupling. This study provides a new method for exploring the mechanism of EECP action and may help to further optimize the EECP technique.

show abstract

Section: Discussionmentioning

confidence: 99%

A study on the immediate effects of enhanced external counterpulsation on physiological coupling

Liu

Hui

et al. 2023

Front. Neurosci.

View full text Add to dashboard Cite

show abstract

“…One way to apply this approach is through the relationship between the signals’ phases ( Federation, 2001 ) to characterize the dynamic alterations of control mechanisms during transition processes ( Negulyaev et al, 2019 ). Previous studies ( Karavaev et al, 2009 ; Ocon et al, 2009 ; Lackner et al, 2011 ; Ocon et al, 2011 ; Zhang et al, 2015 ; Negulyaev et al, 2019 ; Negulyaev et al, 2021 ) have analyzed phase synchronization between cardiovascular and respiratory systems in different contexts, including the course of a healthy pregnancy ( Moertl et al, 2013 ). However, they use the Hilbert Transform without considering the multifrequency nature of cardiovascular signals, so estimating instantaneous phases becomes inappropriate.…”

Section: Introductionmentioning

confidence: 99%

Increased respiratory modulation of cardiovascular control reflects improved blood pressure regulation in pregnancy

et al. 2023

View full text Add to dashboard Cite

Hypertensive pregnancy disorders put the maternal-fetal dyad at risk and are one of the leading causes of morbidity and mortality during pregnancy. Multiple efforts have been made to understand the physiological mechanisms behind changes in blood pressure. Still, to date, no study has focused on analyzing the dynamics of the interactions between the systems involved in blood pressure control. In this work, we aim to address this question by evaluating the phase coherence between different signals using wavelet phase coherence. Electrocardiogram, continuous blood pressure, electrocardiogram-derived respiration, and muscle sympathetic nerve activity signals were obtained from ten normotensive pregnant women, ten normotensive non-pregnant women, and ten pregnant women with preeclampsia during rest and cold pressor test. At rest, normotensive pregnant women showed higher phase coherence in the high-frequency band (0.15-0.4 Hz) between muscle sympathetic nerve activity and the RR interval, blood pressure, and respiration compared to non-pregnant normotensive women. Although normotensive pregnant women showed no phase coherence differences with respect to hypertensive pregnant women at rest, higher phase coherence between the same pairs of variables was found during the cold pressor test. These results suggest that, in addition to the increased sympathetic tone of normotensive pregnant women widely described in the existing literature, there is an increase in cardiac parasympathetic modulation and respiratory-driven modulation of muscle sympathetic nerve activity and blood pressure that could compensate sympathetic increase and make blood pressure control more efficient to maintain it in normal ranges. Moreover, blunted modulation could prevent its buffer effect and produce an increase in blood pressure levels, as observed in the hypertensive women in this study. This initial exploration of cardiorespiratory coupling in pregnancy opens the opportunity to follow up on more in-depth analyses and determine causal influences.

show abstract

The Change in Baroreflex Regulation of Heart Rhythm after “Dry” Immersion Appears during Orthostasis, but not Lower Body Negative Pressure Test

Zhedyaev,

Tarasova,

Semenov

et al. 2024

J Evol Biochem Phys

View full text Add to dashboard Cite

Increase in the Strength of Synchronization between the Baroreflex Waves of Blood Pressure and Heart Rate Due to the Lower Body Negative Pressure Effect

Cited by 3 publications

References 26 publications

A study on the immediate effects of enhanced external counterpulsation on physiological coupling

A study on the immediate effects of enhanced external counterpulsation on physiological coupling

Increased respiratory modulation of cardiovascular control reflects improved blood pressure regulation in pregnancy

The Change in Baroreflex Regulation of Heart Rhythm after “Dry” Immersion Appears during Orthostasis, but not Lower Body Negative Pressure Test

Contact Info

Product

Resources

About