2009
DOI: 10.1007/s11695-009-9890-y
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Increase of Bone Resorption and the Parathyroid Hormone in Postmenopausal Women in the Long-term after Roux-en-Y Gastric Bypass

Abstract: RYGB is associated to high bone resorption and hyperparathyroidism prevalence in postmenopausal women in the long-term. This occurs independently of the intake of calcium, vitamin D status, or ghrelin and does not seem to affect BMD after RYGB.

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Cited by 75 publications
(75 citation statements)
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“…The number of operations for obesity has increased in recent years 5,47 and its success is founded on the effective weight loss, control of comorbidities and increased quality of life 1,5,9,29,47 . However, some negative effects have also been reported in several studies, such as hyperparathyroidism and osteoporosis 39,55,57,59 chronic regurgitation, nutritional deficiencies 2,6,28,30,59 , kidney problems 3,16 and oral problems 22,23,31,49 . The objective of this review was to identify the consequences of postoperative bariatric surgery (as vitamin deficiency, gastroesophageal reflux, kidney disturbances, psychological alterations, reduction of diabetes mellitus, improvement in obstructive sleep apnea and, also, to check its impact on oral health and dental caries, xerostomy, erosion and bone resorption.…”
Section: Introductionmentioning
confidence: 99%
“…The number of operations for obesity has increased in recent years 5,47 and its success is founded on the effective weight loss, control of comorbidities and increased quality of life 1,5,9,29,47 . However, some negative effects have also been reported in several studies, such as hyperparathyroidism and osteoporosis 39,55,57,59 chronic regurgitation, nutritional deficiencies 2,6,28,30,59 , kidney problems 3,16 and oral problems 22,23,31,49 . The objective of this review was to identify the consequences of postoperative bariatric surgery (as vitamin deficiency, gastroesophageal reflux, kidney disturbances, psychological alterations, reduction of diabetes mellitus, improvement in obstructive sleep apnea and, also, to check its impact on oral health and dental caries, xerostomy, erosion and bone resorption.…”
Section: Introductionmentioning
confidence: 99%
“…Valderas JP et al [9] noted that although hyperparathyroidism was seen post RYGB there was no statistical difference in vitamin D, ALP or BMD between their cohort and a matched control. However, both groups did have a vitamin D deficiency, supporting the evidence that the obese continue to have poor diet and vitamin deficiencies are endemic.…”
Section: Discussionmentioning
confidence: 81%
“…However the degree of this loss following bariatric surgery is significantly higher [8]. Further, if bone loss continues after three years then it cannot be explained by weight loss alone, as weight loss should have plateaued and patients may even be regaining weight [9]. This strongly suggests that bone mass loss is not due to weight loss alone and may be explained by the interplay of at least three distinct factors.…”
Section: Obesity Metabolic Disease and The Metabolic Complications Omentioning
confidence: 99%
“…After RYGB, a high prevalence of bone resorption and hyperparathyroidism may exist independent of intake of calcium and Vitamin D status (77,78). This raises a concern that the present recommendations for daily calcium and vitamin D supplementation may not be protective after RYGB, especially in female patients.…”
Section: Vitamin Dmentioning
confidence: 97%