Increase of HLA-DR7 in pigeon breeder's lung in a Mexican population

Selman, Moisés; Terán, L; Mendoza, A. C. De; Camarena, Ángel; Martínez-Cordero, E; Lezama, Margarita; H, Rubio

doi:10.1016/0090-1229(87)90052-3

Cited by 49 publications

(24 citation statements)

References 16 publications

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“…The fact that the nature of the microorganisms (filamentous fungi, actinomycetes, or mycobacteria) tested did not influence the outcome of the final immune response gives weight to the hypothesis that the pathophysiology of HP and the consequent clinical form are due more to the type of exposure (32) and individual genetic susceptibility (33)(34)(35) than to the nature of the microbial environment of the patient.…”

Section: Discussionmentioning

confidence: 99%

Human Monocyte-Derived Dendritic Cells Exposed to Microorganisms Involved in Hypersensitivity Pneumonitis Induce a Th1-Polarized Immune Response

Bellanger

Pallandre

Borg

et al. 2013

Clin Vaccine Immunol

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Section: Discussionmentioning

confidence: 99%

Human Monocyte-Derived Dendritic Cells Exposed to Microorganisms Involved in Hypersensitivity Pneumonitis Induce a Th1-Polarized Immune Response

Bellanger

Pallandre

Borg

et al. 2013

Clin Vaccine Immunol

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“…A number of studies have investigated the relation between the development of HP and various HLA haplotypes with variable results [90][91][92][93][94]. However, a recent polymerase chain reaction (PCR) study has shown conclusively that pigeon fanciers with HP have an increase in the frequency of HLA-DRB1*1305 and HLA-DQB1*0501 alleles and a decrease in the frequency of the HLA-BRB1*0802 allele [95].…”

Section: Pathogenesismentioning

confidence: 98%

Hypersensitivity pneumonitis

Mohr¹

2004

Current Opinion in Pulmonary Medicine

135

138

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A careful environmental and occupational history and establishment of exposure to a known inciting antigen are key factors in making the diagnosis of HP. Serum precipitating antibodies, bronchoalveolar lavage, and lung biopsy may be helpful in making the diagnosis. Avoidance of organic antigen exposure is the most important factor in the management of HP. Corticosteroids are indicated for the treatment of severe acute and subacute HP and for chronic HP that is severe or progressive. Long-term corticosteroid therapy for the treatment of chronic HP should be considered only if objective improvement in clinical signs, pulmonary function, or radiographic abnormalities is documented.

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“…4,5 Esta progresión maligna de las NH es extremadamente rara en otros países, donde la evolución de los pacientes afectados suele ser benigna a pesar de tener estrecha convivencia con aves. [6][7][8] Una de las múltiples diferencias posibles, entre los enfermos de nuestro país y los de otros países, es el ambiente en el que se desarrolla la enfermedad. 9,10 En la Clínica de Fibrosis Pulmonar del INER se le dedica especial atención a estos pacientes y en particular a todos los factores potencialmente involucrados en el curso de la enfermedad.…”

Section: Neumonitis Por Hipersensibilidad En La Ciudad De Méxicounclassified