Increased bleeding risk during percutaneous coronary interventions by arterial hypertension

Abstract

Arterial hypertension is associated with increased risk of bleeding during PCI procedures. © 2015 Wiley Periodicals, Inc.

Atrial Fibrillation and Hypertension

“…Hypertensive patients also have more bleeding complications after percutaneous coronary intervention. 45 Even in hypertensives without AF or any antithrombotic therapy, for example, in survivors of intracranial hemorrhage of any cause, inadequate BP control was strongly associated with about 4-fold higher risk of the hemorrhage recurrence. 46 Important data on the role of hypertension in AF have been provided by recent clinical trials.…”

Short‐versus long‐term Dual Antiplatelet therapy after drug‐eluting stent implantation in women versus men: A sex‐specific patient‐level pooled‐analysis of six randomized trials

“…In patients at high risk of ischemic events, DAPT could prevent fatal thrombotic events . However, prolonged DAPT is associated with increased bleeding and adverse outcomes; it is thus of vital importance to establish optimal DAPT duration . Indeed, bleeding concerns, in parallel with the improved biocompatibility of newer generation stents have led to more uncertainty after several recent randomized controlled trial(s) (RCT) did not show any benefit of prolonging DAPT to 1 year or more versus a shorter course.…”

Strategies for Reducing Vascular and Bleeding Risk for Percutaneous Left Ventricular Assist Device-supported High-risk Percutaneous Coronary Intervention

“…A large retrospective analysis of the Intracoronary Stenting and Antithrombotic Registry randomized controlled trial populations found that patients with a history of hypertension had a 41% greater risk for bleeding events, in particular for non-access-site bleeding (p=0.002), whereas systolic blood pressure at the time of PCI increased the risk for access site bleeding (p=0.018). 10 Patients with hypertension had similar one-year mortality compared with normotensive patients; however, mortality was significantly higher in hypertensive patients with a bleeding event. Thus, optimizing blood pressure control prior to elective, supported PCI is important.…”