Increased brain age and relationships with blood-based biomarkers following concussion in younger populations
Andrew R. Mayer,
Timothy B. Meier,
Josef M. Ling
et al.
Abstract:Objective
Brain age is increasingly being applied to the spectrum of brain injury to define neuropathological changes in conjunction with blood-based biomarkers. However, data from the acute/sub-acute stages of concussion are lacking, especially among younger cohorts.
Methods
Predicted brain age differences were independently calculated in large, prospectively recruited cohorts of pediatric concussion and matched healthy controls (total N = 446), as well a… Show more
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